Results 61 to 70 of about 66,906 (291)

Acylation of monolysocardiolipin in rat heart

Journal of Lipid Research, 1999
Cardiolipin is a major mitochondrial membrane glycerophospholipid in the mammalian heart. In this study, the ability of the isolated intact rat heart to remodel cardiolipin and the mitochondrial enzyme activities that reacylate monolysocardiolipin to ...
Brian J. Ma, William A. Taylor, Vernon W. Dolinsky, Grant M. Hatch   +3 more
doaj   +1 more source

Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples

Journal of Lipid Research, 2006
Cardiolipin is a prominent component of the mitochondrial inner membranes contributing to the regulation of multiple discrete mitochondrial functions. Here, we extend shotgun lipidomics to identify and quantitate cardiolipin molecular species directly ...
Xianlin Han, Kui Yang, Jingyue Yang, Hua Cheng, Richard W. Gross   +4 more
doaj   +1 more source

Changes in membrane lipids drive increased endocytosis following Fas ligation [PDF]

, 2017
Once activated, some surface receptors promote membrane movements that open new portals of endocytosis, in part to facilitate the internalization of their activated complexes.
Degli Esposti, Mauro, Garofalo, Tina, Khosravi Far, Roya, Longo, Agostina, Malorni, Walter, Matarrese, Paola, Misasi, Roberta, Recalchi, Serena, Sorice, Maurizio, Tinari, Antonella   +9 more
core   +1 more source

Wheel and Deal in the Mitochondrial Inner Membranes: The Tale of Cytochrome c and Cardiolipin

Oxidative Medicine and Cellular Longevity, 2020
Cardiolipin oxidation and degradation by different factors under severe cell stress serve as a trigger for genetically encoded cell death programs. In this context, the interplay between cardiolipin and another mitochondrial factor—cytochrome c—is a key ...
A. Díaz-Quintana, Gonzalo Pérez-Mejías, Alejandra Guerra-Castellano, M. A. De la Rosa, I. Díaz-Moreno   +4 more
semanticscholar   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Aplastic Crisis as Primary Manifestation of Systemic Lupus Erythematosus [PDF]

, 2011
Aplastic crisis is an unusual feature of systemic lupus erythematosus (SLE). We report the case of a 54-year-old woman presenting with both (extravascular) Coombs-positive hemolytic anemia and laboratory findings of bone marrow hyporegeneration with ...
Alger M, Andreas Völkl, Bailey FA, Brooks, Chute JP, Espinoza JL, Feng X, Fuat S. Oduncu, Hinterberger-Fischer M, Hirano N, Hirano N, Mestanza-Peralta M, Michael Bäuerle, Pavithran K, Philipp Baumann, Ralf Schmidmaier, Singh NP, Tagoe C, Takamatsu H, Tan EM, Torok-Storb B, Wolach B, Young NS, Young NS   +23 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Membrane curvature induces cardiolipin sorting

Communications Biology, 2019
Cardiolipin is a cone-shaped lipid predominantly localized in curved membrane sites of bacteria and in the mitochondrial cristae. This specific localization has been argued to be geometry-driven, since the CL’s conical shape relaxes curvature frustration.
Elena Beltrán-Heredia, F. Tsai, Samuel Salinas-Almaguer, Francisco J. Cao-García, P. Bassereau, F. Monroy   +5 more
semanticscholar   +1 more source

LL‐37 Driven Phase Transition and Stacking in Oligolamellar Gram‐Negative Bacterial Membrane Models

Advanced Functional Materials, EarlyView.
This work establishes oligolamellar bacterial membrane models to investigate how LL‐37 disrupts the complex dual‐bilayer architecture of Gram‐negative bacteria. Combining SAXS, cryo‐TEM, electrophoretic mobility measurements, and coarse‐grained simulations, it reveals cardiolipin‐driven phase transitions leading to bicelle‐like structures and membrane ...
Bettina Tran, Diane C.A. Lima, Linda Sandblad, Madeleine Ramstedt, Thereza A. Soares, Stefan Salentinig   +5 more
wiley   +1 more source

Uncovering the mechanisms of host mitochondrial cardiolipin release in syphilis: Insights from human microvascular endothelial cells

International Journal of Medical Microbiology
The release of host mitochondrial cardiolipin is believed to be the main factor that contributes to the production of anti-cardiolipin antibodies in syphilis.
Xi Luo, Xiaoyuan Xie, Litian Zhang, Yanqiang Shi, Bo Fu, Liyan Yuan, Yan Zhang, Yinbo Jiang, Wujian Ke, Bin Yang   +9 more
doaj   +1 more source