Results 121 to 130 of about 53,087 (243)

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra, Laurent Chatre, Benoit Bernay, Julien Pontin, Mirjam F. Mastik, Azuwerus van Buiten, Dalibor Nakládal, Bastiaan S. Star, Jan‐Luuk Hillebrands, Guido Krenning   +9 more
wiley   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

Hydrodynamics of Diffusion in Lipid Membrane Simulations

, 2018
By performing molecular dynamics simulations with up to 132 million coarse-grained particles in half-micron sized boxes, we show that hydrodynamics quantitatively explains the finite-size effects on diffusion of lipids, proteins, and carbon nanotubes in ...
Hummer, Gerhard, Köfinger, Jürgen, Vögele, Martin   +2 more
core   +1 more source

cardiolipin

Citation: 'cardiolipin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12989 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

A case of propylthiouracil induced antineutrophil cytoplasmic antibody associated vasculopathy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Nikhil Dwivedi, Jessica Witherspoon, Sarath Bodapati   +2 more
wiley   +1 more source

Noonan Syndrome Spectrum Disorders Predispose to Systemic Lupus Erythematosus: Case Report and Critical Review of the Literature

American Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 1091-1097, May 2026.
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou, Gillian I. Rice, James O'Sullivan, Ben Parker, Ian N. Bruce, Emma Burkitt‐Wright, Tracy A. Briggs   +6 more
wiley   +1 more source

Global Lipidome Workflow for Mycobacterium tuberculosis Using High‐Resolution Mass Spectrometry

Chemistry–Methods, Volume 6, Issue 4, April 2026.
Pre‐extraction cell homogenisation of Mycobacterium tuberculosis (Mtb) enhances lipid recovery by liquid chromatography‐mass spectrometry. Relative to unhomogenised cells, signals for typically triacylglycerol, cardiolipin and phosphatidylethanolamine increase, broadening lipidome coverage and providing a straightforward means to obtain more ...
Glenda Vasku, Nashied Peton, Evelyn Y.‐W. Huang, Madison R. Nuske, Chai Xin Yu, Xiaoxu Chen, Anna K. Coussens, Ivanhoe K. H. Leung   +7 more
wiley   +1 more source

Deficient Cardiolipin Remodelling Alters Muscle Fibre Composition and Neuromuscular Connectivity in Barth Syndrome

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Barth syndrome (BTHS) is a rare X‐linked mitochondrial disorder caused by mutations in the TAFAZZIN gene, which disrupts cardiolipin (CL) remodelling and mitochondrial function. While cardiac manifestations of BTHS are well characterized in male patients, the mechanisms underlying skeletal muscle weakness and fatigability are poorly
Catalina Matias, Paige L. Snider, Elizabeth A. Sierra Potchanant, Joshua R. Huot, Rahul Raghav, Michael T. Chin, Simon J. Conway, Jeffrey J. Brault   +7 more
wiley   +1 more source

Ginsenoside Rg3 Restores Mitochondrial Cardiolipin Homeostasis via GRB2 to Prevent Parkinson's Disease

Advanced Science
Regulating cardiolipin to maintain mitochondrial homeostasis is a promising strategy for addressing Parkinson's disease (PD). Through a comprehensive screening and validation process involving multiple models, ginsenoside Rg3 (Rg3) as a compound capable ...
Li‐Feng‐Rong Qi, Shuai Liu, Qiuyuan Fang, Cheng Qian, Chao Peng, Yuci Liu, Peng Yang, Ping Wu, Ling Shan, Qinghua Cui, Qian Hua, Sen Yang, Cunqi Ye, Wei Yang, Ping Li, Xiaojun Xu   +15 more
doaj   +1 more source

Impact of Fire and Heat Stress on Soil Microorganisms: A Review of Community Changes, Molecular Responses and Plant‐Beneficial Roles

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
This work reviewed the direct and indirect effects of fires on microbial communities and the resilience strategies microbes use to withstand high temperatures . ABSTRACT Fire, whether occurring on the surface or underground, significantly influences soil microbial dynamics by reshaping community composition, functional diversity and overall soil and ...
Ma. del Carmen Orozco‐Mosqueda, Aurora Flores‐Piña, Ajay Kumar, Fannie I. Parra‐Cota, Sergio de los Santos‐Villalobos, Debasis Mitra, Olubukola Oluranti Babalola, Gustavo Santoyo   +7 more
wiley   +1 more source