Results 151 to 160 of about 8,226 (286)

Molecular Dynamics Analysis of Inhibitor Binding Interactions in the Vibrio cholerae Respiratory Complex NQR

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 2, Page 649-659, February 2026.
ABSTRACT The sodium‐pumping ubiquinone oxidoreductase sodium pumping quinone reductase (NQR) is an important enzyme in the respiratory chain of multiple pathogenic gram‐negative bacteria. NQR has been proposed as a viable antibiotic target due to its importance in supporting energy‐consuming reactions and its absence in human cells.
Joseph. A. DePaolo‐Boisvert, Karina Tuz, David. D. L. Minh, Oscar X. Juarez   +3 more
wiley   +1 more source

Acyl‐CoA Binding Protein in White and Brown Adipose Tissue Is Dispensable for Systemic Energy Metabolism in Mice

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim Acyl‐CoA binding protein plays a vital role in lipid metabolism by mediating the intracellular flux and utilization of long‐chain acyl‐CoAs. We generated an adipocyte‐wide ACBP knockout mouse and a brown adipose tissue‐specific ACBP knockout mouse to investigate ACBP function in adipose tissue.
M. F. Nørremark, R. Petersen, P. M. M. Ruppert, E. S. Jul, T. K. Doktor, R. Nielsen, J. F. Kappel, S. Larsen, J. W. Kornfeld, S. Mandrup, B. S. Andresen, J. Havelund, D. Neess, N. J. Færgeman   +13 more
wiley   +1 more source

TRPM8 Regulates Mitochondrial Ca2+‐Dynamics, Temperature and Endoplasmic Reticulum‐Mitochondrial Contact Points in T Cell

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT TRPM8 is a cold temperature‐sensitive and non‐selective Ca2+‐channel. Previously we have observed that TRPM8 is endogenously expressed and affects T cell activation process. Now, we report that TRPM8 regulates functions of mitochondria and ER, two important sub‐cellular compartments.
Tusar Kanta Acharya, Shamit Kumar, Tejas Pravin Rokade, Parnasree Mahapatra, Young Tae Chang, Chandan Goswami   +5 more
wiley   +1 more source

Ischemic Stroke in Hypereosinophilic Syndrome: A Clinicopathologic Study of Two Cases

Neuropathology, Volume 46, Issue 1, February 2026.
ABSTRACT Ischemic stroke is a rare complication of hypereosinophilic syndrome (HES). Manifestations of stroke in HES have been described in the radiologic literature; however the pathologic characterization of central nervous system (CNS) involvement in HES is limited.
Karina C. Martin, Dan Straathof, Chi Lai, Harry V. Vinters   +3 more
wiley   +1 more source

Structural characterization of cardiolipin-driven activation of cytochrome c into a peroxidase and membrane perturbation

, 2018
Dariush Mohammadyani, Naveena Yanamala, Alejandro K. Samhan‐Arias, Alexandr A. Kapralov, G. О. Stepanov, Nick Nuar, Joan Planas-Iglesias, Narinder Sanghera, Valerian E. Kagan, Judith Klein‐Seetharaman   +9 more
openalex   +2 more sources

Cardiolipin Provides a Platform for Caspase-1 Activation and NLRP3 Inflammasome Assembly [PDF]

, 2016
Suzanne L. Cassel, Eric I. Elliott, Shankar S. Iyer, Fayyaz S. Sutterwala   +3 more
openalex   +1 more source

Metabolome Atlas of Brain Reveals Regional Shared and Unique Metabolic Drifts in Response to Type 2 Diabetes in Male Mice

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
A detailed metabolome atlas of the male mouse brain was established, incorporating metabolomic and lipidomic profiling of seven anatomical regions. T2D induced marked metabolic alterations, which were mainly associated with lipotoxicity, defective energy metabolism, proinflammatory processes, and neurotoxicity.
Yang Zhou, Yitong Lu, Zhaobao Wang, Xiaoqian Du, Bei Jiang, Qiuhui Xuan   +5 more
wiley   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, Volume 16, Issue 1, Page 11-24, January 2026.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Barth Syndrome: Connecting Cardiolipin to Cardiomyopathy

, 2017
Nikita Ikon, Robert O. Ryan
openalex   +1 more source

Función y biogénesis mitocondrial [PDF]

, 2005
El objetivo principal de esta tesis se ha centrado en el estudio de las diferencias entre ratas macho y hembra en la morfología, la función y la biogénesis mitocondrial del tejido adiposo marrón (TAM) y del hígado, mediante el análisis de distintas ...
Departament de Biologia Fonamental i Ciències de la Salut, Justo López, Roberto   +1 more
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