Results 31 to 40 of about 4,774 (217)
Background Lipid-protein interactions stabilize protein oligomers, shape their structure, and modulate their function. Whereas in vitro experiments already account for the functional importance of lipids by using natural lipid extracts, in silico methods
Kristyna Pluhackova, Andreas Horner
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2357 Lost and found: Detection of brain cardiolipins in plasma after cardiac arrest
OBJECTIVES/SPECIFIC AIMS: Neurological injury remains as the main limiting factor for overall recovery after cardiac arrest (CA). Currently available indicators of neurological injury are inadequate for early prognostication after return of spontaneous ...
Andrew M. Lamade +9 more
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Lipidomics in Health and Diseases - Beyond the Analysis of Lipids [PDF]
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Fan, P, Li, M, Wang, Y
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Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors [PDF]
Detergents enable the purification of membrane proteins and are indispensable reagents instructural biology. Even though a large variety of detergents have been developed in the lastcentury, the challenge remains to identify guidelines that allowfine ...
Almeida, F. +12 more
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Crosstalk between the lipopolysaccharide and phospholipid pathways during outer membrane biogenesis in Escherichia coli [PDF]
The outer membrane of gram-negative bacteria is composed of phospholipids in the inner leaflet and lipopolysaccharides (LPS) in the outer leaflet. LPS is an endotoxin that elicits a strong immune response from humans, and its biosynthesis is in part ...
Andrews, SS +3 more
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The interaction of dietary fats and carbohydrates on liver mitochondria were examined in male FBNF1 rats fed 20 different low-fat isocaloric diets.
Irina G. Stavrovskaya +7 more
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A Five-Year Update on Matrix Compounds for MALDI-MS Analysis of Lipids
Matrix-assisted laser desorption and ionization (MALDI) is a widely used soft-ionization technique of modern mass spectrometry (MS). MALDI enables the analysis of nearly all chemical compounds—including polar and apolar (phospho)lipids—with a minimum ...
Jenny Leopold +3 more
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The molecular mechanism of transport by the mitochondrial ADP/ATP carrier [PDF]
Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open and matrix-open states.
Aleksandrova, Antoniya A. +7 more
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Structure of Cardiolipin [PDF]
PANGBORN1 considered that the glycerylglycero-phosphate skeleton of cardiolipin contained three phosphoric acid and four glycerol residues (I), the six available hydroxyl groups in this structure being esterified with unsaturated fatty acids in the intact phospholipid.
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Cardiolipin Interactions with Proteins [PDF]
Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria with four acyl chains and two phosphate groups that have been implicated in numerous functions from energy metabolism to apoptosis. Many proteins are known to interact with CL, and several cocrystal structures of protein-CL complexes exist.
Planas-Iglesias, Joan +5 more
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