Results 31 to 40 of about 4,774 (217)

Native-like membrane models of E. coli polar lipid extract shed light on the importance of lipid composition complexity

open access: yesBMC Biology, 2021
Background Lipid-protein interactions stabilize protein oligomers, shape their structure, and modulate their function. Whereas in vitro experiments already account for the functional importance of lipids by using natural lipid extracts, in silico methods
Kristyna Pluhackova, Andreas Horner
doaj   +1 more source

2357 Lost and found: Detection of brain cardiolipins in plasma after cardiac arrest

open access: yesJournal of Clinical and Translational Science, 2018
OBJECTIVES/SPECIFIC AIMS: Neurological injury remains as the main limiting factor for overall recovery after cardiac arrest (CA). Currently available indicators of neurological injury are inadequate for early prognostication after return of spontaneous ...
Andrew M. Lamade   +9 more
doaj   +1 more source

Lipidomics in Health and Diseases - Beyond the Analysis of Lipids [PDF]

open access: yes, 2014
published_or_final_versio
Fan, P, Li, M, Wang, Y
core   +1 more source

Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors [PDF]

open access: yes, 2020
Detergents enable the purification of membrane proteins and are indispensable reagents instructural biology. Even though a large variety of detergents have been developed in the lastcentury, the challenge remains to identify guidelines that allowfine ...
Almeida, F.   +12 more
core   +2 more sources

Crosstalk between the lipopolysaccharide and phospholipid pathways during outer membrane biogenesis in Escherichia coli [PDF]

open access: yes, 2016
The outer membrane of gram-negative bacteria is composed of phospholipids in the inner leaflet and lipopolysaccharides (LPS) in the outer leaflet. LPS is an endotoxin that elicits a strong immune response from humans, and its biosynthesis is in part ...
Andrews, SS   +3 more
core   +1 more source

Dietary macronutrients modulate the fatty acyl composition of rat liver mitochondrial cardiolipins[S]

open access: yesJournal of Lipid Research, 2013
The interaction of dietary fats and carbohydrates on liver mitochondria were examined in male FBNF1 rats fed 20 different low-fat isocaloric diets.
Irina G. Stavrovskaya   +7 more
doaj   +1 more source

A Five-Year Update on Matrix Compounds for MALDI-MS Analysis of Lipids

open access: yesBiomolecules, 2023
Matrix-assisted laser desorption and ionization (MALDI) is a widely used soft-ionization technique of modern mass spectrometry (MS). MALDI enables the analysis of nearly all chemical compounds—including polar and apolar (phospho)lipids—with a minimum ...
Jenny Leopold   +3 more
doaj   +1 more source

The molecular mechanism of transport by the mitochondrial ADP/ATP carrier [PDF]

open access: yes, 2019
Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open and matrix-open states.
Aleksandrova, Antoniya A.   +7 more
core   +1 more source

Structure of Cardiolipin [PDF]

open access: yesNature, 1958
PANGBORN1 considered that the glycerylglycero-phosphate skeleton of cardiolipin contained three phosphoric acid and four glycerol residues (I), the six available hydroxyl groups in this structure being esterified with unsaturated fatty acids in the intact phospholipid.
openaire   +2 more sources

Cardiolipin Interactions with Proteins [PDF]

open access: yesBiophysical Journal, 2015
Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria with four acyl chains and two phosphate groups that have been implicated in numerous functions from energy metabolism to apoptosis. Many proteins are known to interact with CL, and several cocrystal structures of protein-CL complexes exist.
Planas-Iglesias, Joan   +5 more
openaire   +2 more sources

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