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Coronavirus Disease 2019 and Cardiometabolic Disease

Cardiology in Review, 2021
Cardiometabolic disease describes a combination of metabolic abnormalities that increases the risk of type 2 diabetes and cardiovascular diseases, including pathological changes such as insulin resistance, hyperglycemia, dyslipidemia, abdominal obesity, and hypertension, and environmental risk factors such as smoking, sedentary lifestyle, poor diet ...
Chan W, Kim, Wilbert S, Aronow, William H, Frishman   +2 more
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Circulating Microbiota in Cardiometabolic Disease

Frontiers in Cellular and Infection Microbiology, 2022
The rapid expansion of microbiota research has significantly advanced our understanding of the complex interactions between gut microbiota and cardiovascular, metabolic, and renal system regulation. Low-grade chronic inflammation has long been implicated as one of the key mechanisms underlying cardiometabolic disease risk and progression, even before ...
Keiichi Sumida, Zhongji Han, Chi-Yang Chiu, Tahliyah S. Mims, Amandeep Bajwa, Ryan T. Demmer, Ryan T. Demmer, Susmita Datta, Csaba P. Kovesdy, Csaba P. Kovesdy, Joseph F. Pierre   +10 more
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Inflammatory markers and cardiometabolic diseases [PDF]

Acta Clinica Belgica, 2015
A growing body of evidence emerges that obesity, metabolic syndrome, type 2 diabetes and cardiovascular disease are intimately related to chronic inflammation.A narrative review summarizing the most recent data of the literature describing the pathological implications of inflammation in obese patients with cardiometabolic disorders.Besides high ...
ESSER, Nathalie, Paquot, Nicolas, Scheen, André   +2 more
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Uric acid and cardiometabolic diseases [PDF]

Clinical Hypertension, 2020
AbstractHyperuricemia, which has been considered as a cause of gout and nephrolithiasis has recently been suggested to be associated with hypertension, coronary heart disease, heart failure, atrial fibrillation, insulin resistance, and nonalcoholic fatty liver disease.
Seung Jae Lee, Byeong Kil Oh, Ki-Chul Sung   +2 more
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Calpain and Cardiometabolic Diseases

International Journal of Molecular Sciences, 2023
Calpain is delineated as a superfamily of cysteine proteases containing a CysPC motif within their genes. Among the fifteen species of mammalian homologs, calpain-1 and -2, which are categorized as conventional isozymes, execute limited proteolysis in a calcium-dependent fashion.
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GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy

Journal of Lipid Research, 2017
GPR40 and GPR120 are fatty acid sensors that play important roles in glucose and energy homeostasis. GPR40 potentiates glucose-dependent insulin secretion and demonstrated in clinical studies robust glucose lowering in type 2 diabetes.
Santhosh Satapati, Ying Qian, Margaret S. Wu, Aleksandr Petrov, Ge Dai, Sheng-ping Wang, Yonghua Zhu, Xiaolan Shen, Eric S. Muise, Ying Chen, Emanuel Zycband, Adam Weinglass, Jerry Di Salvo, John S. Debenham, Jason M. Cox, Ping Lan, Vinit Shah, Stephen F. Previs, Mark Erion, David E. Kelley, Liangsu Wang, Andrew D. Howard, Jin Shang   +22 more
doaj   +1 more source

Fibrinogen is associated with glucose metabolism and cardiovascular outcomes in patients with coronary artery disease

Cardiovascular Diabetology, 2020
Background The present cohort study aims to examine the relationship between fibrinogen (Fib) levels and glucose metabolism [fasting blood glucose (FBG) and hemoglobin A1c (HbA1c)] and investigate the impact of high Fib on cardiovascular outcomes in ...
Shuo-Lin Liu, Na-Qiong Wu, Hui-Wei Shi, Qian Dong, Qiu-ting Dong, Ying Gao, Yuan-Lin Guo, Jian-Jun Li   +7 more
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Glucagon receptor antagonism induces increased cholesterol absorption[S]

Journal of Lipid Research, 2015
Glucagon and insulin have opposing action in governing glucose homeostasis. In type 2 diabetes mellitus (T2DM), plasma glucagon is characteristically elevated, contributing to increased gluconeogenesis and hyperglycemia.
Hong-Ping Guan, Xiaodong Yang, Ku Lu, Sheng-Ping Wang, Jose M. Castro-Perez, Stephen Previs, Michael Wright, Vinit Shah, Kithsiri Herath, Dan Xie, Daphne Szeto, Gail Forrest, Jing Chen Xiao, Oksana Palyha, Li-Ping Sun, Paula J. Andryuk, Samuel S. Engel, Yusheng Xiong, Songnian Lin, David E. Kelley, Mark D. Erion, Harry R. Davis, Liangsu Wang   +22 more
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Landscape of cardiometabolic risk factors in Chinese population: a narrative review

Cardiovascular Diabetology, 2022
With rapid economic growth and changes at all levels (including environmental, social, individual), China is facing a cardiovascular disease (CVD) crisis. In China, more than 40% of deaths are attributable to CVDs, and the number of CVD deaths has almost
Jian-Jun Li, Hui-Hui Liu, Sha Li
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Prognostic value of N-terminal Pro–B-Type natriuretic peptide in patients with intermediate coronary lesions

Frontiers in Cardiovascular Medicine, 2022
BackgroundThe optimal treatment strategy for patients with coronary intermediate lesions, defined as diameter stenosis of 50–70%, remains a great challenge for cardiologists.
Chenxi Song, Chenxi Song, Sheng Yuan, Sheng Yuan, Kongyong Cui, Kongyong Cui, Zhongxing Cai, Zhongxing Cai, Rui Zhang, Rui Zhang, Jining He, Jining He, Zheng Qiao, Zheng Qiao, Xiaohui Bian, Xiaohui Bian, Shaoyu Wu, Shaoyu Wu, Haoyu Wang, Haoyu Wang, Rui Fu, Rui Fu, Chunyue Wang, Chunyue Wang, Qianqian Liu, Qianqian Liu, Dong Yin, Dong Yin, Lei Jia, Lei Jia, Kefei Dou, Kefei Dou   +31 more
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