Results 31 to 40 of about 4,979,977 (315)

Cardiometabolic HFpEF: mechanisms and therapies [PDF]

, 2021
Heart failure with preserved ejection fraction (HFpEF) accounts for at least half of all patients with heart failure (HF) and is projected to be the most common form of HF in the near feature.
Hill, J.A., Schiattarella, G.G.
core   +1 more source

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey[S]

Journal of Lipid Research, 2016
SREBP cleavage-activating protein (SCAP) is a key protein in the regulation of lipid metabolism and a potential target for treatment of dyslipidemia. SCAP is required for activation of the transcription factors SREBP-1 and -2.
Kristian K. Jensen, Marija Tadin-Strapps, Sheng-ping Wang, James Hubert, Yanqing Kan, Yong Ma, David G. McLaren, Stephen F. Previs, Kithsiri B. Herath, Ablatt Mahsut, Andy Liaw, Shubing Wang, Steven J. Stout, CarolAnn Keohan, Gail Forrest, David Coelho, Satya Yendluri, Stephanie Williams, Martin Koser, Steven Bartz, Karen O. Akinsanya, Shirly Pinto   +21 more
doaj   +1 more source

Prognostic value of N-terminal Pro–B-Type natriuretic peptide in patients with intermediate coronary lesions

Frontiers in Cardiovascular Medicine, 2022
BackgroundThe optimal treatment strategy for patients with coronary intermediate lesions, defined as diameter stenosis of 50–70%, remains a great challenge for cardiologists.
Chenxi Song, Chenxi Song, Sheng Yuan, Sheng Yuan, Kongyong Cui, Kongyong Cui, Zhongxing Cai, Zhongxing Cai, Rui Zhang, Rui Zhang, Jining He, Jining He, Zheng Qiao, Zheng Qiao, Xiaohui Bian, Xiaohui Bian, Shaoyu Wu, Shaoyu Wu, Haoyu Wang, Haoyu Wang, Rui Fu, Rui Fu, Chunyue Wang, Chunyue Wang, Qianqian Liu, Qianqian Liu, Dong Yin, Dong Yin, Lei Jia, Lei Jia, Kefei Dou, Kefei Dou   +31 more
doaj   +1 more source

Cardiometabolic risk markers in Indian children: comparison with UK Indian and white European children [PDF]

, 2012
Objective: UK Indian adults have higher risks of coronary heart disease and type 2 diabetes than Indian and UK European adults. With growing evidence that these diseases originate in early life, we compared cardiometabolic risk markers in Indian, UK ...
Veena Sargoor R., Cook Derek G., Whincup, PH, Derek G Cook, Alicja R Rudnicka, Claire M. Nightingale (168851), Rudnicka Alicja R., Fall, CH, Cook, Derek G., Whincup Peter H., Hill, Jacqueline C., Hill, JC, Ghattu V Krishnaveni, Fall, Caroline H.D., Jacqueline C. Hill (168872), Peter H. Whincup (168892), Krishnaveni Ghattu V., Owen, Christopher G., Jacqueline C Hill, Fall Caroline H. D., Rudnicka, AR, Derek G. Cook (168879), Nightingale, Claire M., Nightingale Claire M., Nightingale, CM, Sargoor R Veena, Caroline H D Fall, Rudnicka, Alicja R., Veena, Sargoor R., Veena, SR, Sargoor R. Veena (168867), Owen Christopher G., Owen, CG, Krishnaveni, Ghattu V., Hill Jacqueline C., Krishnaveni, GV, Caroline H. D. Fall (168887), Cook, DG, Claire M Nightingale, Ghattu V. Krishnaveni (168855), Christopher G. Owen (168863), Alicja R. Rudnicka (168859), Whincup, Peter H., Christopher G Owen, Peter H Whincup   +44 more
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Synergistic effect of the commonest residual risk factors, remnant cholesterol, lipoprotein(a), and inflammation, on prognosis of statin-treated patients with chronic coronary syndrome

Journal of Translational Medicine, 2022
Background Currently, remnant cholesterol (RC), lipoprotein(a) [Lp(a)], and inflammation are considered the principal residual cardiovascular risk (RCVR) factors.
Hui-Hui Liu, Yuan-Lin Guo, Cheng-Gang Zhu, Na-Qiong Wu, Ying Gao, Rui-Xia Xu, Qian Dong, Jie Qian, Ke-Fei Dou, Jian-Jun Li   +9 more
doaj   +1 more source

Cardiometabolic diseases.

Revista brasileira de epidemiologia = Brazilian journal of epidemiology, 2019
Cardiometabolic diseases are prevalent in populations and are among the leading causes of death. Objective: This sub-study of the Health, Well-being and Aging (SABE) study describes the self-reported prevalence of diabetes mellitus (DM), hypertension, and atherosclerotic cardiovascular disease (CVD) for its three waves (2000, 2006, and 2010).
Sandra Roberta Gouvea, Ferreira, Alexandre Dias Porto, Chiavegatto Filho, Maria Lúcia, Lebrão, Yeda Aparecida de Oliveira, Duarte, Ruy, Laurenti   +4 more
openaire   +2 more sources

Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]

, 2010
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J, Landwehrmeyer, G Bernhard, Aileen K Ho, Bisson, Jonathan Ian, Schwenke C, David Craufurd, Dunnett, Stephen B., Handley, Olivia, Investigators of the European Huntington's Disease Network, The, DI MARIA, EMILIO, Craufurd D, Dunnett, SB, Carsten Schwenke, the investigators of the European Huntington's Disease Network, Craufurd, David, Edward Wild, Landwehrmeyer, GB, Busse, Monica, Rosser, Anne Elizabeth, Olivia J Handley, Romano Silvia., Tabrizi SJ, Ho, Aileen K., Wild, E, Landwehrmeyer GB, Craufurd, D, Tabrizi, SJ, Tabrizi, Sarah J., Handley, OJ, Rickards, Hugh, Dunnett, Stephen, Ho, Aileen K, Orth, Michael, Ho, AK, Wild, Edward, Stephen B. Dunnett, Sarah J Tabrizi, Wild, EJ, Landwehrmeyer, G. Bernhard, Naji, Jenny, Landwehrmeyer, G. Bernhard, Wild E, Investigators of the European Huntington's Disease Network, Handley, Olivia J., Orth, M, Ellison-Rose, Lynda, Tabrizi, Sarah J, Price, Kathleen, Ho AK, ABBRUZZESE, GIOVANNI, Schwenke, C, Ho, A, Orth M, Handley OJ, Schwenke, Carsten, Dunnett SB, Dunnett, Stephen B, Michael Orth, G. Bernhard Landwehrmeyer   +59 more
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Cardiometabolic Diseases

JACC: Basic to Translational Science, 2023
[Figure: see text]
openaire   +2 more sources

Genetic prediction of medication use patterns in cardiometabolic disease

, 2023
By performing a large-scale biobank-based genome-wide association study, we identified a strong link between the underlying risk of cardiometabolic disease and patterns of lifelong medication use in hyperlipidemia, hypertension and type 2 diabetes.
Kiiskinen, Tuomo, Ripatti, Samuli
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Thigh fat and muscle each contribute to excess cardiometabolic risk in South Asians, independent of visceral adipose tissue. [PDF]

, 2014
To compare fat distribution and associations between fat depots and cardiometabolic traits in South Asians and ...
Wright, A, Hughes, AD, Peter Whincup, Eastwood, SV, Chaturvedi, N, Whincup, P, Tillin, T, Nita G. Forouhi, Therese Tillin, Ian Godsland, Mayet, J, Forouhi, NG, Godsland, I, Jamil Mayet, Alun D Hughes, Andrew Wright, Sophie V. Eastwood, Nishi Chaturvedi   +17 more
core   +1 more source