Results 31 to 40 of about 86,843 (267)

Histone Deacetylases and Cardiometabolic Diseases [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2015
Cardiometabolic disease, emerging as a worldwide epidemic, is a combination of metabolic derangements leading to type 2 diabetes mellitus and cardiovascular disease. Genetic and environmental factors are linked through epigenetic mechanisms to the pathogenesis of cardiometabolic disease.
Kan Hui, Yiew, Tapan K, Chatterjee, David Y, Hui, Neal L, Weintraub   +3 more
openaire   +2 more sources

Development and Validation of a Nomogram for Predicting the Risk of Adverse Cardiovascular Events in Patients with Coronary Artery Ectasia

Journal of Cardiovascular Development and Disease, 2021
Coronary artery ectasia (CAE) is a rare finding and is associated with poor clinical outcomes. However, prognostic factors are not well studied and no prognostication tool is available.
Zhongxing Cai, Yintang Wang, Luqi Li, Haoyu Wang, Chenxi Song, Dong Yin, Weihua Song, Kefei Dou   +7 more
doaj   +1 more source

Social isolation, loneliness, and incident type 2 diabetes mellitus: results from two large prospective cohorts in Europe and East Asia and Mendelian randomizationResearch in context

EClinicalMedicine, 2023
Summary: Background: Social isolation and loneliness pose significant public health challenges globally. The objective of this study is to investigate the association between social isolation, loneliness, and the risk of type 2 diabetes mellitus (T2DM).
Yanjun Song, Chen Zhu, Boqun Shi, Chenxi Song, Kongyong Cui, Zhen'ge Chang, Guofeng Gao, Lei Jia, Rui Fu, Qiuting Dong, Lei Feng, Chenggang Zhu, Dong Yin, JoAnn E. Manson, Kefei Dou   +14 more
doaj   +1 more source

Magnesium Deficiency and Cardiometabolic Disease

Nutrients, 2023
Magnesium (Mg2+) has many physiological functions within the body. These include important roles in maintaining cardiovascular functioning, where it contributes to the regulation of cardiac excitation–contraction coupling, endothelial functioning and haemostasis.
Remi Fritzen, Amy Davies, Miriam Veenhuizen, Matthew Campbell, Samantha J. Pitt, Ramzi A. Ajjan, Alan J. Stewart   +6 more
openaire   +3 more sources

Intensified glycemic control by HbA1c for patients with coronary heart disease and Type 2 diabetes: a review of findings and conclusions

Cardiovascular Diabetology, 2023
The occurrence and development of coronary heart disease (CHD) are closely linked to fluctuations in blood glucose levels. While the efficacy of intensified treatment guided by HbA1c levels remains uncertain for individuals with diabetes and CHD, this ...
Jingyang Chen, Dong Yin, Kefei Dou
doaj   +1 more source

Lipids Metabolism and Cardiometabolic Diseases

International Journal of Molecular Sciences, 2023
Cardiometabolic diseases (CMD) remains the major cause of morbidity and mortality in Western countries, with a marked increased in the last years [...]
Melania Gaggini, Cristina Vassalle
openaire   +3 more sources

Relationship of PCSK9 levels with indices of vascular function and subclinical atherosclerosis in patients with familial dyslipidemias

Hellenic Journal of Cardiology, 2019
Objective: Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels predict cardiovascular risk. We aimed to determine the correlation of PCSK9 levels with predictors of cardiovascular risk, such as central hemodynamics and carotid intima-media ...
Charalambos Vlachopoulos, Iosif Koutagiar, Dimitrios Terentes-Printzios, Ioannis Skoumas, Angeliki Rigatou, Antigoni Miliou, Alexandros-Nikitas Skliros, Stavroula Pantou, Kostantinos Filis, Dimitrios Tousoulis   +9 more
doaj   +1 more source

The Prevalence of Familial Hypercholesterolemia (FH) in Chinese Patients With Acute Myocardial Infarction (AMI): Data From Chinese Acute Myocardial Infarction (CAMI) Registry

Frontiers in Cardiovascular Medicine, 2020
Background: The prevalence of familial hypercholesterolemia (FH) in the patients with acute myocardial infarction (AMI) in China is unclear.Materials and Methods: In China Acute Myocardial Infarction (CAMI) Registry, 13,002 patients with age 18–80 were ...
Hui-Wei Shi, Jin-Gang Yang, Yang Wang, Wei Li, Yuan-Lin Guo, Ying Gao, Yi-Da Tang, Jian-Jun Li, Na-Qiong Wu, Yue-Jin Yang   +9 more
doaj   +1 more source

In the heart of adipobiology: cardiometabolic disease

Biomedical Reviews, 2009
Published on 1 December 1994 issue of Nature, the Jeffrey Friedman's discovery "gave leptin in the beginning" of the endocrine saga of adipose tissue. Onwards, studies on this tissue have enjoyed an explosive growth that conceptualized a novel field of research, adipobiology.
Chaldakov GN, Fiore M, Tonchev AB, Rancic G, Hristova MG, Tuncel N, Kostov DD, Nikolova V, Bojanic V, Aloe L   +9 more
openaire   +2 more sources

Heart Failure in Indonesia: A Growing Burden Beyond Conventional Care

Majalah Kardiologi Indonesia
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Vebiona Kartini Prima Putri, Siti Elkana Nauli, Anggia Chairuddin Lubis   +2 more
doaj   +1 more source