Results 11 to 20 of about 86,843 (267)
Inflammatory markers and cardiometabolic diseases [PDF]
Acta Clinica Belgica, 2015 A growing body of evidence emerges that obesity, metabolic syndrome, type 2 diabetes and cardiovascular disease are intimately related to chronic inflammation.A narrative review summarizing the most recent data of the literature describing the pathological implications of inflammation in obese patients with cardiometabolic disorders.Besides high ...
ESSER, Nathalie +2 more
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Thrombosis Journal, 2021 Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) is considered to have multiple roles in the development of atherosclerosis, which is recently reported to participate in the thrombotic process. We aimed to examine the relationship between
Jia Peng +9 more
doaj +1 more source
Di-san junyi daxue xuebao, 2022 Objective To investigate the correlation between cumulative exposure to metabolic factors and progression of lower extremity arterial disease (LEAD) in patients with type 2 diabetes mellitus (T2DM).
YOU Mei +4 more
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GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy
Journal of Lipid Research, 2017 GPR40 and GPR120 are fatty acid sensors that play important roles in glucose and energy homeostasis. GPR40 potentiates glucose-dependent insulin secretion and demonstrated in clinical studies robust glucose lowering in type 2 diabetes.
Santhosh Satapati +22 more
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CaMKII in Cardiometabolic Disease
Aging, 2014 The worldwide epidemic of obesity is closely linked to insulin resistance and type 2 diabetes (T2D), which have led to a critical need for new drug development. Insulin resistance and T2D contribute to the pathogenesis of many diseases including fatty liver disease, cardiovascular disease, kidney failure and retinal disease.
Lale, Ozcan, Ira, Tabas
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Glucagon receptor antagonism induces increased cholesterol absorption[S]
Journal of Lipid Research, 2015 Glucagon and insulin have opposing action in governing glucose homeostasis. In type 2 diabetes mellitus (T2DM), plasma glucagon is characteristically elevated, contributing to increased gluconeogenesis and hyperglycemia.
Hong-Ping Guan +22 more
doaj +1 more source
Cardiovascular Diabetology, 2020 Background The present cohort study aims to examine the relationship between fibrinogen (Fib) levels and glucose metabolism [fasting blood glucose (FBG) and hemoglobin A1c (HbA1c)] and investigate the impact of high Fib on cardiovascular outcomes in ...
Shuo-Lin Liu +7 more
doaj +1 more source
Landscape of cardiometabolic risk factors in Chinese population: a narrative review
Cardiovascular Diabetology, 2022 With rapid economic growth and changes at all levels (including environmental, social, individual), China is facing a cardiovascular disease (CVD) crisis. In China, more than 40% of deaths are attributable to CVDs, and the number of CVD deaths has almost
Jian-Jun Li, Hui-Hui Liu, Sha Li
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Reviews in Cardiovascular Medicine, 2022 Background: Transradial artery (TRA) access for percutaneous coronary intervention (PCI) was associated with lower risks of major bleeding and vascular complications compared to transfemoral artery access.
Hao Wang +8 more
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The incretin system and cardiometabolic disease [PDF]
Canadian Journal of Cardiology, 2010 Rates of type 2 diabetes, obesity and their associated detrimental cardiovascular effects are rapidly increasing. Despite the availability of several treatment options for type 2 diabetes and the use of intensive regimens combining several antidiabetic drugs, less than one-half of all patients reach a target glycosylated hemoglobin level of less than 7%
Paul E, Szmitko +2 more
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