Results 91 to 100 of about 171,003 (305)

Sleep During Pregnancy: The nuMoM2b Pregnancy and Sleep Duration and Continuity Study [PDF]

, 2017
Study Objectives: To characterize sleep duration, timing and continuity measures in pregnancy and their association with key demographic variables. Methods: Multisite prospective cohort study. Women enrolled in the nuMoM2b study (nulliparous women
Basner, Robert C., Chung, Judith H., Facco, Francesca L., Grobman, William A., Haas, David M., Herbas, Marcos, Hunter, Shannon, Iams, Jay, Louis, Judette M., Manchanda, Shalini, Nhan-Chang, Chia-Lang, Parker, Corette B., Parry, Samuel, Pien, Grace W., Reid, Kathryn J., Saade, George R., Silver, Robert M., Simhan, Hyagriv N., Wing, Deborah A., Zee, Phyllis C.   +19 more
core   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

The Prevalence and Awareness of Cardiometabolic Risk Factors in Southern Chinese Population with Coronary Artery Disease

The Scientific World Journal, 2013
Background. Cardiometabolic risk factors significantly accelerate the progression of coronary artery disease (CAD); however, whether CAD patients in South China are aware of the prevalence of these risk factors is not clear yet. Methods.
Xinrui Li, Yuan Zhang, Min Wang, Xiaofei Lv, Dongfang Su, Zhongxia Li, Ding Ding, Min Xia, Jian Qiu, Gang Hu, Wenhua Ling   +10 more
doaj   +1 more source

Perception of neighborhood crime and drugs Increases cardiometabolic risk in Chilean adolescents [PDF]

, 2014
PURPOSE: Studies report an association between neighborhood risk and both obesity and cardiometabolic risk factors (CMR) among adolescents. Here we describe the effect of perceived neighborhood risk on adiposity and CMR among Chilean adolescents ...
Blanco, Estela, Burrows, Raquel, Delva, Jorge, Gahagan, Sheila, Lozoff, Betsy, Martinez, Suzanna M., Reyes, Marcela   +6 more
core   +2 more sources

Clusters of longitudinal risk profile trajectories are associated with cardiometabolic diseases: Results from the population-based KORA cohort.

PLoS ONE
BackgroundMultiple risk factors contribute jointly to the development and progression of cardiometabolic diseases. Therefore, joint longitudinal trajectories of multiple risk factors might represent different degrees of cardiometabolic risk.MethodsWe ...
Fiona Niedermayer, Gunther Schauberger, Wolfgang Rathmann, Stefanie J Klug, Barbara Thorand, Annette Peters, Susanne Rospleszcz   +6 more
doaj   +1 more source

Cardiorespiratory Fitness Is Inversely Associated With Clustering of Metabolic Syndrome Risk Factors: The Ball State Adult Fitness Program Longitudinal Lifestyle Study

, 2018
Objective: The focus of this study was the association between the metabolic syndrome (MetSyn) and cardiorespiratory fitness (CRF) defined as maximal oxygen uptake (VO2max). Although previous research has shown a relationship between MetSyn and CRF, most
Finch, Holmes, Harber, Matthew P., Imboden, Mary T., Kaminsky, Leonard A., Kelley, Elizabeth, Whaley, Mitchell H.   +5 more
core   +1 more source

Altilix\uae Supplement Containing Chlorogenic Acid and Luteolin Improved Hepatic and Cardiometabolic Parameters in Subjects with Metabolic Syndrome: A 6 Month Randomized, Double-Blind, Placebo-Controlled Study [PDF]

, 2019
The objective was to evaluate the eects of 6 months of supplementation with Altilix\uae, containing chlorogenic acid and its derivatives, and luteolin and its derivatives, on cardiovascular risk and hepatic markers in subjects with metabolic syndrome ...
Angelo M. Patti, Antonella Amato, Antonio Mag\ue1n-Fern\ue1ndez, Arrigo F. G. Cicero, Dragana Nikolic, Giuseppa Castellino, Giuseppe Antonio Malfa, Giuseppe Montalto, Maciej Banach, Manfredi Rizzo, Peter P. Toth, Roberta Chianetta   +11 more
core   +2 more sources

The metabolic inter-relationships between changes in waist circumference, triglycerides, insulin sensitivity and small, dense low-density lipoprotein particles with acute weight loss in clinically obese children and adolescents. [PDF]

, 2013
OBJECTIVE: Small, dense low-density lipoprotein (LDL) particles are highly atherogenic and strongly associated with obesity-related dyslipidemia. The metabolic inter-relationships between weight loss induced changes in waist circumference, triglycerides,
Albers, Bioletto, Cole, Conwell, Davies, Davis, Epstein, Ferguson, Gately, Huelsing, Jebb, Kang, Kang, King, Kolsgaard, Lamarche, Magnussen, Matthews, Miyashita, Monzavi, Morrison, Pinhas-Hamiel, Reinehr, Reinehr, Savoye, Schofield, Shalitin, Steinberger, Wang, Willi, Zambon   +30 more
core   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Some doubts about the mantra on the deleterious cardiovascular effects of sulfonylureas [PDF]

, 2017
[No abstract ...
Prudente, Sabrina, Trischitta, Vincenzo
core   +1 more source