Results 141 to 150 of about 146,196 (353)

Induction of Methuosis in Breast Cancer Stem Cells by a Cobalt(III) Complex Evokes Immunotherapeutic Response

Angewandte Chemie, EarlyView.
Cancer stem cells (CSCs) drive metastasis, relapse and resist conventional apoptosis‐inducing chemotherapies. We report a cobalt(III)‐cyclam complex with pyrene and diflunisal moieties that reduces the viability of breast CSCs at low micromolar concentrations.
Jiaxin Fang, Sijie Wen, Xiao Feng, Hao Ren, Kuldip Singh, Haihua Xiao, Lingpu Zhang, Kogularamanan Suntharalingam   +7 more
wiley   +2 more sources

Corrigendum to “Studies on solvent precipitation of levan synthesized using Bacillus subtilis MTCC 441” [Heliyon 5 (9) (September 2019) e02414]

Heliyon, 2019
C.A.C. Jothi Sailaja, V. Bhuvaneshwari, Kartik Kumar Sarwareddy, Krishna Priya Mani, Saravanan Ramiah Shanmugam, V. Ponnusami   +5 more
doaj   +1 more source

Confocal cardiomyocyte sub-cellular measurements.

, 2019
Confocal cardiomyocyte sub-cellular measurements.
Timothy L. M. Jones (6569954), Anthony J. Hickey (388291), Amelia S. Power (6569951), Marie-Louise Ward (5576849), Ruth Norman (841390)   +4 more
core   +1 more source

Cytokines and Cardiomyocyte Death

Annals of Medicine, 1997
Cytokines have been associated with the pathogenesis of acute coronary syndromes and chronic heart failure (CHF), which are both associated with cardiomyocyte loss. In CHF, increased serum concentrations of proinflammatory cytokines, including tumour necrosis factor alpha (TNF-alpha) and also soluble TNF receptor have been found.
openaire   +2 more sources

Cardiomyocyte DNA synthesis and binucleation during murine development

, 1996
Cardiomyocyte DNA synthesis and binucleation indexes were determined during murine development. Cardiomyocyte DNA synthesis occurred in two temporally distinct phases.
K. K. Kim, M. Franklin, M. H. Soonpaa, L. Pajak, L. J. Field   +4 more
core   +1 more source

Engineering Intelligent iPSC Biomanufacturing: Integrating Robotic Automation, AI, and Process Control

Advanced Intelligent Systems, EarlyView.
This review highlights recent advances in automated iPSC culture systems integrating robotics, advanced imaging, artificial intelligence, and process control. These technologies improve reproducibility, scalability, and quality in cell expansion, differentiation, and real‐time monitoring, while emerging AI‐enabled and closed‐loop approaches offer new ...
Hyoryong Lee, Roma Desai, Byunggik Kim, Deok‐Ho Kim   +3 more
wiley   +1 more source

Kir2.1 Channel Contributes to Hypokalemia-Induced Abnormal Pacemaker Activities of Cardiomyocytes With Inward Rectification

Frontiers in Bioscience-Landmark
Background: Hypokalemia induces abnormal spontaneous pacemaker activities of cardiomyocytes, which is strongly associated with fatal cardiac arrhythmias caused by hypokalemia. However, the mechanism remains unclear.
Jinhua Lv, Yangxin Jiang, Jin Zeng, Dongchuan Zuo   +3 more
doaj   +1 more source

Systematic Cardiac Phenotyping of Patients With Copy Number Variants in the 15q11.2 Breakpoint 1 to Breakpoint 2 Region: A Retrospective Cohort Study From Nine Pediatric Cardiac Centers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Microdeletions impacting 15q11.2 breakpoint (BP) 1 to BP2, adjacent to the Prader–Willi critical region, have previously described neuropsychiatric associations, with potential low penetrance presentations of congenital heart disease (CHD) also identified.
Morgan B. Wright, Maria B. Padua, Lindsey R. Helvaty, Kim L. McBride, Gabrielle Geddes, Vidu Garg, Seema R. Lalani, Stephanie Burns Wechsler, Jennelle C. Hodge, Benjamin J. Landis, Stephanie M. Ware   +10 more
wiley   +1 more source

Refining a preclinical model of viral myocarditis in accordance with biotech standards

Animal Models and Experimental Medicine, EarlyView.
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen, Julia Riedesel, Juliane Stein, Brandon H. Greene, Svenja Rohde, Sonja Suess, Bjoern Keiner, Priya Panjwani, Padmapriya Ponnuswamy, Juan E. Camacho Londoño   +9 more
wiley   +1 more source

Lead Exposure During Differentiation Perturbs Electrophysiological Function in iPSC Derived Cardiomyocytes in a Cell Line-Dependent Manner [PDF]

Kimberley E. Sala-Hamrick, Esha K Shah, André Monteiro da Rocha, Laurie Kathleen Svoboda   +3 more
openalex   +1 more source