Results 161 to 170 of about 103,439 (265)

Molecular Regulation of Cardiomyocyte Cell Cycle and Regeneration. [PDF]

Biology (Basel)
Li F, Son Y, Yang M, Zhu W.
europepmc   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Multicellular senescence programs in the aged heart. [PDF]

J Mol Cell Cardiol Plus
Bultot L, Tsurudome N, Kumazaki E, Shimizu I.   +3 more
europepmc   +1 more source

Cardiomyocyte Data

Data from the Cardiomyocyte section for the paper. We include sum projections of all confocal images and then ilastik files such as the DNA Mask (pixel probabilities), Object Classification (To identify the cardiomyocytes), and the CSV file with nuclear ...
Nicholas Joseph Russell, Archan Chakraborty, Paulo Belato, Don Fox   +3 more
core  

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

CHK1 activates mitophagy to attenuate cardiac aging via inhibiting AHSA1-ubiquitination. [PDF]

Redox Biol
Jing P, Zhou LH, Chen SX, Chen JY, Gu LF, Yang TT, Wang SB, Du C, Chen YX, Wang QM, Wang LS, Wang H.   +11 more
europepmc   +1 more source

Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes

Biotechnology and Bioengineering, EarlyView.
Human pluripotent stem cells were differentiated to cTnT+ cardiomyocytes and imaged throughout the process using phase contrast. We predicted differentiation efficiency (cTnT+ area) from phase contrast and compared model performance with a live‐cell cTnT‐GFP reporter.
Austin K. Feeney, Yaniv Ovadia, Aaron D. Simmons, Christian Elabd, Claire J. Peplinski, Frank Li, Sean P. Palecek   +6 more
wiley   +1 more source

Beyond Reperfusion: Early Molecular Drivers and Therapeutic Opportunities in Acute Post-Infarction Cardiac Fibrosis. [PDF]

Int J Mol Sci
Tan D, Lye YE, Patel P, Minn NA, Le AC, Bobik A, Kyaw T.   +6 more
europepmc   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Correction: Comprehensive analysis of the transcriptome-wide m6A methylome of heart via MeRIP after birth: day 0 vs. day 7

Frontiers in Cardiovascular Medicine
Chuanxi Yang, Kun Zhao, Jing Zhang, Xiaoguang Wu, Wei Sun, Xiangqing Kong, Xiangqing Kong, Jing Shi   +7 more
doaj   +1 more source