Results 191 to 200 of about 144,668 (287)

ROS-Mediated Cardiomyocyte Proliferation and Myocardial Regeneration: Mechanisms and Targeted Strategies for Ischemic Heart Disease. [PDF]

J Cardiovasc Dev Dis
Chen M, Liu T, Sun F, Tian X, Zheng W, Zhu Z, Wang W.   +6 more
europepmc   +1 more source

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

BMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang, Jiawei Cui, Jin Wang, Manfred F. Maitz, Rifang Luo, Yunbing Wang   +5 more
wiley   +1 more source

Gut microbiota-derived trimethylamine N-oxide contributes to cardiomyocyte pyroptosis and cardiac injury via the tRF-Glu-ANT1-GSDMD axis. [PDF]

Cell Mol Biol Lett
Wang T, Ren W, Chen X, Wang X, Liu M, Zhang Y, Li Z, Wang Y, Song Z, Diao H.   +9 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

The Role of Histone Methylation in Heart Failure: Epigenetic Mechanisms and Therapeutic Perspectives. [PDF]

Drug Des Devel Ther
Zhou Y, Dong Z, Gao Y, Xiao K, Huang Q, Cao Q, Wang X, Duan Y, Guo Z, Wei J.   +9 more
europepmc   +1 more source

Fibroblast-Derived Microfibrillar-Associated Protein 5 Exerts Cardioprotective Effects After Myocardial Infarction by Activating the NOTCH2 Signaling in Cardiomyocytes. [PDF]

J Am Heart Assoc
Guo J, Gu Z, Lin M, Tao H, Jiang Y, Zhang R, Jia D, Zhang N, You S, Sun Y, Jia P.   +10 more
europepmc   +1 more source

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment—Real‐World Historical Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh, Ofek Levi, Nili Stein, Amir Yahav, Naomi Gronich   +4 more
wiley   +1 more source

Evidence of Cardiotoxic Immune Activation by Triple Immune Checkpoint Blockade: A Translational Alert for Clinical Surveillance in Patients With Cancer. [PDF]

J Cardiovasc Pharmacol
Quagliariello V, Passariello M, Belardo M, Esposito A, Paone M, Berretta M, Iovine M, Barbato M, Canale ML, Paccone A, Inno A, Oliva S, Maurea C, Forte P, Mauriello A, Fonderico C, Gallucci G, Tarantini L, Camilli M, Camerini A, De Lorenzo C, Maurea N.   +21 more
europepmc   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

miR-138-5p Promotes HF in Rats by Reducing Histone Methylation in the Myd88 Promoter Region through Inhibition of EZH2. [PDF]

Acta Cardiol Sin
Zhang Y, Lu W.
europepmc   +1 more source