Results 171 to 180 of about 103,439 (265)

Peripartum-Associated Heart Failure Develops Independently of RHOT Proteins. [PDF]

Int J Mol Sci
Froese N, Sina E, Galuppo P, Werlein C, Gigina A, Hegermann J, Geffers R, Scholz T, Kamp JC, Neubert L, Schneider J, Ricke-Hoch M, Dietl A, Bauersachs J, Riehle C.   +14 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Sustained β-catenin activation via GSK3 inhibition promotes direct fibroblast-to-cardiomyocyte reprogramming. [PDF]

J Biol Chem
Wang X, Anwar I, Pratt RE, Dzau VJ, Hodgkinson CP.   +4 more
europepmc   +1 more source

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

BMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang, Jiawei Cui, Jin Wang, Manfred F. Maitz, Rifang Luo, Yunbing Wang   +5 more
wiley   +1 more source

Effects of Pharmacological Polyploidization in Human iPSC‐Derived Cardiomyocytes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Nicholas Strash, Marisa Patsy, Sophia DeLuca, Abbigail Helfer, Xixian Jiang, Tianyu Wu, Nenad Bursac   +6 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Subthreshold Thermal Stress Aggravates Methamphetamine-Induced Cardiomyocyte Pyroptosis via the Mitochondrial ROS/BAX/mtDNA/NLRP3 Pathway. [PDF]

Int J Mol Sci
Wang M, Hou C, Hu M, Zhou D, Wang X, Jin M, Ma C, Shi J, Ni Z.   +8 more
europepmc   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

The Pivotal Role of Plant Derivatives and Eicosanoid Signaling Modulation in Counteracting Cardiomiopathy. [PDF]

Int J Mol Sci
Ussia S, Ritorto G, Macrì R, Serra M, Tavernese A, Altomare C, Dardano DM, Idone C, Palma E, Muscoli C, Volterrani M, Barillà F, Mollace V, Mollace R.   +13 more
europepmc   +1 more source

Protocol for fibrin-based endothelial-cardiomyocyte co-culture in a microfluidic device. [PDF]

STAR Protoc
Spanjersberg TCF, Klaassen A, Wubbolts R, van Dijk CGM, van der Velden J, Veltrop RJA, van der Harst P, Harakalova M, van Steenbeek FG.   +8 more
europepmc   +1 more source