Results 181 to 190 of about 144,668 (287)

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

Arthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento Da Conceicao, Neelanjan Vishnu, Shankara N Varadarajan, Venugopal R. Bovilla, Rajender K Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

MCPPIR promotes cardiomyocyte proliferation and cardiac repair via o8G oxidation of POC1B mRNA. [PDF]

Cardiovasc Res
Wang T, Chen XZ, Xu HF, Wang JX, Ren JH, Zhou LY, Liu CY, Li XM, Wang YQ, Yang SM, Zhang MH, Zhang YH, Lin KY, Tian JW, Wang K.   +14 more
europepmc   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Correction: Comprehensive analysis of the transcriptome-wide m6A methylome of heart via MeRIP after birth: day 0 vs. day 7

Frontiers in Cardiovascular Medicine
Chuanxi Yang, Kun Zhao, Jing Zhang, Xiaoguang Wu, Wei Sun, Xiangqing Kong, Xiangqing Kong, Jing Shi   +7 more
doaj   +1 more source

Restoration of RBM22 overcomes the transcriptional and epigenetic barriers of cardiomyocyte proliferation for heart regeneration. [PDF]

Nat Commun
Duan X, Tan Y, Zhang Y, Wang B, Zhang S, Li T, Liu X, Zhan Z.   +7 more
europepmc   +1 more source

Genetically and metabolically corrected pluripotent stem cells from patients with mtDNA disease [PDF]

, 2015
Ahmed, Riffat, Amato, Paula, Belmonte, Juan Carlos Izpisua, Folmes, Clifford DL, Gutierrez, Nuria Marti, Hayama, Tomonari, Huang, Taosheng, Kang, Eunju, Koski, Amy, Laurent, Louise C, Lee, Yeonmi, Li, Ying, Ma, Hong, Ma, Li, Mitalipov, Nargiz, Mitalipov, Shoukhrat, Mora-Castilla, Sergio, Morey, Robert, Ocampo, Alejandro, Poulton, Joanna, Terzic, Andre, Tippner-Hedges, Rebecca, Van Dyken, Crystal, Wang, Xinjian, Wolf, Don P, Wu, Jun   +25 more
core   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

<i>Sirt1</i> Promotes Cardiomyocyte Differentiation Through the XR_951230.1/miR-3663-3p/SMYD1 Axis. [PDF]

Genes (Basel)
Li C, Mahemuti M, Maimaiti Y, Wang T, Zhang X, Jiapaer Z.   +5 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Effects of Pharmacological Polyploidization in Human iPSC‐Derived Cardiomyocytes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Nicholas Strash, Marisa Patsy, Sophia DeLuca, Abbigail Helfer, Xixian Jiang, Tianyu Wu, Nenad Bursac   +6 more
doaj   +1 more source