Results 221 to 230 of about 144,668 (287)

Cardiomyocyte-Specific modRNA-Induced FoxM1 Overexpression Promotes Recovery From Myocardial Infarction in Adult Mammals. [PDF]

Circulation
Wu Y, Nguyen T, Wang Y, Zhou Y, Zhao J, Wang Y, Walcott GP, Garry DJ, Nakada Y, Zhang J.   +9 more
europepmc   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source

Enhancing KLF15 activity in cardiomyocytes: a novel approach to prevent pathological reprogramming and fibrosis via nuclease-deficient dCas9VPR. [PDF]

Signal Transduct Target Ther
Schoger E, Kim R, Bleckwedel F, Peralta TM, Priesmeier L, Fischer JA, Stengel L, Rocha C, Santos GL, Lutz S, Boileau E, Baumgarten N, Schulz MH, Dieterich C, Müller OJ, Cyganek L, Cabrera-Orefice A, Eberl H, Maack C, Streckfuss-Bömeke K, Pavez-Giani MG, Doroudgar S, Sossalla S, Zelarayán LC.   +23 more
europepmc   +1 more source

T-tubular remodeling occurs in a cardiomyocyte-autonomous manner following pathological mechanical stiffness exposure. [PDF]

J Mol Cell Cardiol Plus
Ibrahim M, Courelli V, Cheng L, Song L, Pamias-Lopez B, Vite A, Toubat O, Pitoulis F, Prosser B, Margulies K.   +9 more
europepmc   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Pathogenic role of mitochondrial DNA mutations in heart failure: clinical features, mechanisms, and therapeutic prospects. [PDF]

Front Cardiovasc Med
Ni M, Zheng A, Zheng H, Jia W, Wang Y, Peng Y, Yao C, Wei Y, Wang X, Kang S.   +9 more
europepmc   +1 more source

Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner, Antje Augstein, Mahmoud Abdellatif, André Lourenço, Adelino Leite‐Moreira, Inês Falcão‐Pires, Sarah Werner, Holger Thiele, Simon Sedej, Antje Schauer, Volker Adams   +10 more
wiley   +1 more source

VSNL1 attenuates hypoxia‑induced myocardial apoptosis by regulating the CNP/NPRB pathway. [PDF]

Mol Med Rep
Yang X, Fang W, Chang R, Ma L, Chen X, Li Y.   +5 more
europepmc   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source