Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely +14 more
wiley +1 more source
An Integrated Evaluation Framework for Adult Heart Regeneration. [PDF]
Li Y, Liu X, Zhou X, Nie Y, Feng J.
europepmc +1 more source
Refining fibroblast-to-cardiomyocyte transdifferentiation protocols to explore emergent self-organization in cardiac cultures. [PDF]
Turchaninova E +13 more
europepmc +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai +4 more
wiley +1 more source
Abstract Aims SPARCL1 was recently identified as a biomarker of right ventricular (RV) maladaptation in patients with pulmonary hypertension (PH), and N‐terminal pro‐brain natriuretic protein (NT‐proBNP) is an established biomarker of RV failure in PH. The present study investigated whether NT‐proBNP and SPARCL1 concentrations are associated with load ...
Oliver Dörr +15 more
wiley +1 more source
RMC-6272, a selective third-generation bi-steric mTORC1 inhibitor, improves cardiac function in pressure overload-induced cardiac hypertrophy. [PDF]
Rogge M +8 more
europepmc +1 more source
Screening and Identification of BMP5 as a Key Regulatory Gene for hPSCs Transcardiomyocyte Differentiation. [PDF]
Zhang H +8 more
europepmc +1 more source
O-GlcNAcylation as a Metabolic Integrator in Cardiovascular Physiology and Disease. [PDF]
Malik SS, Pi X, Xie L.
europepmc +1 more source
Engineering cardiac regeneration using stem cells: Cellular sources, differentiation signatures, targeted delivery, and functional recovery. [PDF]
Gupta S +8 more
europepmc +1 more source
Correction: Uric acid promotes myocardial infarction injury via activating Pyrin domain-containing 3 inflammasome and reactive oxygen species/transient receptor potential melastatin 2/Ca2 + pathway. [PDF]
Wu H, Dai R, Wang M, Chen C.
europepmc +1 more source

