Results 11 to 20 of about 305,984 (384)

Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect

Nature Genetics, 2021
The heart muscle diseases hypertrophic (HCM) and dilated (DCM) cardiomyopathies are leading causes of sudden death and heart failure in young, otherwise healthy, individuals. We conducted genome-wide association studies and multi-trait analyses in HCM (1,
Rafik Tadros, Catherine Francis, Xiao Yun Xu, Alexa M.C. Vermeer, Andrew R. Harper, Roy Huurman, Ken Kelu Bisabu, Roddy Walsh, Edgar T. Hoorntje, Wouter P. te Rijdt, Rachel Buchan, Hannah G. van Velzen, Marjon A. van Slegtenhorst, Jentien M. Vermeulen, Joost A. Offerhaus, Wenjia Bai, Antonio de Marvao, Najim Lahrouchi, Leander Beekman, Jacco C. Karper, Jan H. Veldink, Elham Kayvanpour, Antonis Pantazis, A. John Baksi, Nicola Whiffin, Francesco Mazzarotto, Geraldine Sloane, Hideaki Suzuki, Deborah Schneider-Luftman, Paul Elliott, Pascale Richard, Flavie Ader, Eric Villard, Peter Lichtner, Thomas Meitinger, Michael W.T. Tanck, J. Peter van Tintelen, Andrew Thain, David McCarty, Robert A. Hegele, Jason D. Roberts, Julie Amyot, Marie‐Pierre Dubé, Julia Cadrin‐Tourigny, Geneviève Giraldeau, Philippe L. L’Allier, Patrick Garceau, Jean‐Claude Tardif, S. Matthijs Boekholdt, R Thomas Lumbers, Folkert W. Asselbergs, Paul J.R. Barton, Stuart A. Cook, Sanjay Prasad, Declan P. O’Regan, Jolanda van der Velden, Karin J. H. Verweij, Mario Talajic, Guillaume Lettre, Yigal M. Pinto, Benjamin Meder, Philippe Charron, Rudolf A. de Boer, Imke Christiaans, Michelle Michels, Arthur A.M. Wilde, Hugh Watkins, Paul M. Matthews, James S. Ware, Connie R. Bezzina   +69 more
openalex   +3 more sources

Cardiomyopathies: An Overview [PDF]

International Journal of Molecular Sciences, 2021
Background: Cardiomyopathies are a heterogeneous group of pathologies characterized by structural and functional alterations of the heart. Aims: The purpose of this narrative review is to focus on the most important cardiomyopathies and their epidemiology, diagnosis, and management. Methods: Clinical trials were identified by Pubmed until 30 March 2021.
Ciarambino T., Menna G., Sansone G., Giordano M.   +3 more
openaire   +4 more sources

Cardiomyopathies: Temporal Review and Genetic Determination [PDF]

Biomedicines
Cardiomyopathies are a heterogeneous group of diseases of the myocardium associated with dysfunction, with or without a structural substrate. They are frequently genetically determined. The dysfunction may be mechanical, both of the systole and diastole,
Gaetano Thiene, Stefania Rizzo, Cristina Basso   +2 more
doaj   +2 more sources

Sex‐Related Differences in Genetic Cardiomyopathies

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Cardiomyopathies are a heterogeneous collection of diseases that have in common primary functional and structural abnormalities of the heart muscle, often genetically determined.
Alessia Argirò, Carolyn Ho, Sharlene M. Day, Jolanda van der Velden, Elisabetta Cerbai, Sara Saberi, Jil C. Tardiff, Neal K. Lakdawala, Iacopo Olivotto   +8 more
doaj   +2 more sources

Overview of Cardiomyopathies in Childhood

Frontiers in Pediatrics, 2021
Paediatric cardiomyopathies are a heterogenous group of rare disorders, characterised by mechanical and electrical abnormalities of the heart muscle. The overall annual incidence of childhood cardiomyopathies is estimated at about 1 per 100,000 children ...
Anika Rath, Robert Weintraub, Robert Weintraub, Robert Weintraub   +3 more
doaj   +2 more sources

Mitochondrial cardiomyopathies [PDF]

Frontiers in Cardiovascular Medicine, 2016
Mitochondria are found in all nucleated human cells and perform a variety of essential functions, including the generation of cellular energy. Mitochondria are under dual genome control.
Ayman W. El-Hattab, Fernando Scaglia
doaj   +3 more sources

Reversible Cardiomyopathies

Clinical Medicine Insights: Cardiology, 2015
Cardiomyopathies (CMs) have many etiological factors that can result in severe structural and functional dysregulation. Fortunately, there are several potentially reversible CMs that are known to improve when the root etiological factor is addressed.
Harsh Patel, Raef Madanieh, Constantine E. Kosmas, Satya K. Vatti, Timothy J. Vittorio   +4 more
doaj   +4 more sources

Inherited cardiomyopathies [PDF]

BMJ, 2019
Miles, C, Fanton, Z, Tome, M, Behr, ER
openaire   +5 more sources

Validation of the new American College of Cardiology/American Heart Association Guidelines for the risk stratification of sudden cardiac death in a large Mediterranean cohort with Hypertrophic Cardiomyopathy

Hellenic Journal of Cardiology, 2022
Background: The aim of our study was to assess the performance of the new American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines, with respect to sudden cardiac death (SCD) prevention, in comparison with the established risk ...
Thomas Zegkos, Georgios Tziomalos, Despoina Parcharidou, Dimitris Ntelios, Christos A. Papanastasiou, Efstratios Karagiannidis, Thomas Gossios, Pavlos Rouskas, Sotiris Katranas, Stilianos Paraskevaidis, Haralambos Karvounis, Georgios Efthimiadis   +11 more
doaj   +1 more source

Survival of patients with cardiomyopathies [PDF]

Българска кардиология, 2021
Cardiomyopathies are a heterogeneous group of diseases. The main pathogenetic mechanism is myocardial damage due to genetic mutations. Cardiomyopathies are one of the leading causes of heart failure, sudden cardiac death, and life-threatening arrhythmias.
Monika Shumkova, Kiril Karamfiloff, Raya Ivanova, Kristina Stoyanova, Dobrin Vassilev   +4 more
doaj   +3 more sources