Results 151 to 160 of about 66,165 (233)

Genetic Spectrum, Clinical Characteristics, and Molecular Pathogenesis of Hypertrophic Cardiomyopathy Requiring Heart Transplantation. [PDF]

J Cardiovasc Dev Dis
Andreeva S, Korneva L, Marusova M, Sazonova Y, Gudkova A, Streltsova A, Fetisova S, Simonenko M, Fanta A, Semenov A, Bortsova M, Mitrofanova L, Moiseeva O, Bobylev A, Gavrilova L, Vikhlyantsev I, Fedotov P, Kostareva A.   +17 more
europepmc   +1 more source

Tissue‐Specific Extraction and Structural Elucidation of Actin‐Tropomyosin‐Myosin Complexes from Human and Rodent

Aggregate, Volume 7, Issue 1, January 2026.
We developed a general tissue‐extraction strategy that directly purifies native F‐actin and actin–tropomyosin–myosin (ATM) complexes from human and rodent muscles for cryo‐EM. Near‐atomic structures, including an HCM R404Q mouse model, reveal how a disease myosin mutation remodels ATM assembly and alters myosin conformation at the actin interface ...
Danni Li, Qinyue Zhao, Youqi Tao, Shiran Lv, Wanbing Zhao, Yunxia Li, Xingyu Xiong, Zhizhi Wang, Wenqing Xu, Yaoyang Zhang, Cong Liu, Weidong Le, Wenyan Kang, Dan Li, Qin Cao, Bin Dai   +15 more
wiley   +1 more source

Risk Stratification and Optimal Use of Implantable Cardioverter-Defibrillator Therapy in Primary Prevention of Sudden Cardiac Death in Genetic Cardiomyopathies, with Assessment of the Role of Genetic Variants in Guiding Therapeutic Decisions. [PDF]

Biomedicines
Ruscio E, Scacciavillani R, Gurgoglione FL, Pinnacchio G, Bencardino G, Perna F, Narducci ML, Pelargonio G, Niccoli G, Locorotondo G, Burzotta F.   +10 more
europepmc   +1 more source

Advances and Applications of Spatial Proteomics: From Organellar Maps to Clinical Translation

ChemBioChem, Volume 27, Issue 1, January 2026.
Spatial proteomics provides high‐resolution maps of protein localization and trafficking by combining advanced mass spectrometry with complementary imaging and computational tools. Emerging low‐input and automated workflows are expanding its applicability to challenging clinical samples, supporting mechanistic disease research and biomarker discovery ...
Chiara Bernardini, Maike Däther, Franziska R. Traube   +2 more
wiley   +1 more source

Computational identification of necroptosis-related hub genes and therapeutic targets in dilated cardiomyopathy via integrated analysis of bulk and single-cell RNA sequencing public cohorts. [PDF]

Medicine (Baltimore)
Xia M, Ji Y, Zhu H.
europepmc   +1 more source

Changes of Serum CTRP12 in Patients With Coronary Artery Disease After the Treatment of Percutaneous Coronary Intervention and Its Relationship With In‐Stent Restenosis

Clinical Cardiology, Volume 49, Issue 1, January 2026.
Serum CTRP12 levels are significantly lower in CAD patients, and significant correlate to disease severity and dynamic changes after PCI. They may serve as a potential biomarker for diagnosing CAD and predicting ISR occurrence. ABSTRACT Background C1q/tumor necrosis factor‐related protein 12 (CTRP12) plays a protective role in coronary artery disease ...
Botao Zhao, Yuchao Shen
wiley   +1 more source

Titin Cardiomyopathy, Emerging Evidence: More Than A Big Heart. [PDF]

Curr Cardiol Rep
Angriman F, Bortolotti F, Perotto M, Artioli R, Radesich C, Paldino A, Collesi C, Zacchigna S, Sinagra G, Dal Ferro M.   +9 more
europepmc   +1 more source

Association of the Geriatric Nutritional Risk Index With Prognosis in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
ABSTRACT Background and Aims The geriatric nutritional risk index (GNRI) has shown good predictive value for some diseases. However, its association with major adverse cardiovascular events (MACEs) in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) remains uncertain.
Yuewen Qi, Xinchen Wang, Yan Liu, Ying Zhang, Qiyu Sun, Chen Wei, Ge Song, Jingyi Liu, Fei Shi, Lixian Sun   +9 more
wiley   +1 more source

Dilated Cardiomyopathy [PDF]

, 2020
openaire   +2 more sources

Postmortem Diagnosis of Dilated Cardiomyopathy: A Systematic Review Revisiting Fundamentals. [PDF]

Diagnostics (Basel)
Calabrese S, Cianci V, Sapienza D, Nicolosi A, Spadaro B, Ieni A, Speranza D, Gualniera P, Asmundo A, Mondello C.   +9 more
europepmc   +1 more source