Effect of Four Crystalloid Cardioplegias on Immature Rabbit Hearts During Global Ischaemia
Controversy surrounds the reported beneficial effects of crystalloid cardioplegic solutions in the immature myocardium. In the present study, we investigated the efficacy of four clinical cardioplegic solutions in the immature myocardium to determine if ...
Yunqing Mei +5 more
doaj +1 more source
Adequate distribution of warm cardioplegic solution [PDF]
Seventy-five patients undergoing coronary artery bypass grafting were randomized to receive warm antegrade (N = 25), warm retrograde (N = 25), or a combination of warm antegrade and retrograde (N = 25) delivery of blood cardioplegic solution. Myocardial oxygen utilization, lactate and acid metabolism, and adenine nucleotides and their degradation ...
Hayashida, Nobuhiko +8 more
openaire +2 more sources
St. Thomas Modified Cardioplegia Effects on Myoblasts’ Viability and Morphology
Background and Objectives: The cardioplegic arrest of the heart during cardiosurgical procedures is the crucial element of a cardioprotection strategy. Numerous clinical trials compare different cardioplegic solutions and cardioprotective protocols, but ...
Rafał Nowicki +7 more
doaj +1 more source
Custodiol-N, the novel cardioplegic solution reduces ischemia/reperfusion injury after cardiopulmonary bypass [PDF]
Backgrounds: On the basis of Custodiol preservation and cardioplegic solution a novel cardioplegic solution was developed to improve the postischemic cardiac and endothelial function.
Karck, Matthias +4 more
core +1 more source
Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle [PDF]
Background - Although pharmacological block of the slow, delayed rectifier potassium current (I-Ks) by chromanol 293B, L-735,821, or HMR-1556 produces little effect on action potential duration (APD) in isolated rabbit and dog ventricular myocytes, the ...
Biliczki, Péter +10 more
core +1 more source
Minimally Invasive Mitral Valve Surgery I: Patient Selection, Evaluation, and Planning. [PDF]
Widespread adoption of minimally invasive mitral valve repair and replacement may be fostered by practice consensus and standardization. This expert opinion, first of a 3-part series, outlines current best practices in patient evaluation and selection ...
Agnihotri, Arvind K +24 more
core +1 more source
Cardioplegic solution: A contamination crisis
Eleven patients were given varying doses of cardioplegic solution contaminated with Enterobacter cloacae. Five patients died. Early bleeding, necessitating reoperation, occurred in eight patients and a total of 126 units of blood and 203 units of platelets were given (range 2 to 19 and 15 to 47 units, respectively).
C F, Hughes +3 more
openaire +2 more sources
Solução cardioplégica polarizante: estado da arte Polarizing cardioplegic solution: state of the art
A exegese do termo cardioplegia remete aos significados de "lesão, golpe, ataque ou ferimento", bem diferente, portanto, do sentido em que o termo é empregado na maior parte dos centros de cirurgia cardíaca do Brasil e do mundo, ou seja, como ...
Marcos Aurélio Barboza de Oliveira +3 more
doaj +1 more source
Human cardiac tissue in a microperfusion chamber simulating extracorporeal circulation - ischemia and apoptosis studies [PDF]
Background After coronary artery bypass grafting ischemia/reperfusion injury inducing cardiomyocyte apoptosis may occur. This surgery-related inflammatory reaction appears to be of extreme complexity with regard to its molecular, cellular and tissue ...
Engin Usta +36 more
core +1 more source
The long saphenous vein is the most used conduit in cardiac surgery, but its long-term patency is limited by vein graft disease (VGD). Endothelial dysfunction is a key driver of VGD; its aetiology is multi-factorial.
Georgia R. Layton +6 more
doaj +1 more source

