Results 211 to 220 of about 46,462 (246)

Future Cardioprotective Considerations

Journal of Cardiac Surgery, 1993
Remarkable strides have been made in perioperative myocardial protection for heart operations. Recent advances in understanding the physiology of myocardial ischemia and its protective responses suggest that there is a possibility for further improvement.
A S, Wechsler, A, Abd-Elfattah
openaire   +2 more sources

Tocotrienols in Cardioprotection

2007
Tocotrienols, a group of Vitamin E stereoisomers, offer many health benefits including their ability to lower cholesterol levels, and provide anticancer and tumor-suppressive activities. Several recent studies determined the cardioprotective abilities of tocotrienols, although the number is only 1% compared to the study with tocopherols.
Samarjit, Das, Kalanithi, Nesaretnam, Dipak K, Das   +2 more
openaire   +3 more sources

KININS AND CARDIOPROTECTION

Pharmacological Research, 1997
During the past decade it was recognised that kinins are potent endogenous vasoactive peptides with important cardioprotective actions which are of therapeutic relevance in the acute and chronic beneficial effects of ACE inhibitors. The effect of kinins is mediated through the release of autocoids from the endothelium, particularly nitric oxide (NO ...
K J, Wirth, W, Linz, G, Wiemer, B A, Schölkens   +3 more
openaire   +2 more sources

Cardioprotective growth factors

Cardiovascular Research, 2009
Many of the originally identified cardiovascular 'growth factors' have been demonstrated to exert a diverse variety of actions within the cardiovascular system, the majority of which are unrelated to their initially proposed mechanism of action. Interestingly, several of these growth factors have been demonstrated to protect the cardiomyocyte from the ...
Derek J, Hausenloy, Derek M, Yellon
openaire   +2 more sources

Sildenafil and Cardioprotection

Current Pharmaceutical Design, 2013
The phosphodiesterese-5 (PDE5) inhibitors, including sildenafil (Viagra™), vardenafil (Levitra™), tadalafil (Cialis™) and avanafil (Stendra™) have been developed for the treatment of erectile dysfunction. Moreover, sildenafil and tadalafil have been approved for the management of pulmonary arterial hypertension.
openaire   +2 more sources

Antioxidants and Cardioprotection

Medicine & Science in Sports & Exercise, 2007
Limiting myocardial ischemia-reperfusion (IR) injury is essential for preventing contractile dysfunction and limiting morbidity and mortality associated with ischemic heart disease. Over the last few decades, it has become clear that during IR insults, myocardial oxygen radical formation is accelerated and plays a critical role in mediating cellular ...
openaire   +2 more sources

Prolylcarboxypeptidase: A cardioprotective enzyme

The International Journal of Biochemistry & Cell Biology, 2009
Prolylcarboxypeptidase (PRCP) is involved in regulating the blood flow through active tissues in order to preserve the internal environment. The expression of PRCP in tissues is determined by a number of pharmacological stimuli such as glucocorticoids and a combination of dexamethasone plus the mu-opioid receptor agonist [D-Ala2, N-Me-Phe4, Gly5-ol ...
J, Mallela, J, Yang, Z, Shariat-Madar
openaire   +2 more sources

Inhalational Anaesthetics and Cardioprotection

2008
The heart has a strong endogenous cardioprotection mechanism that can be triggered by short periods of ischaemia (like during angina) and protects the myocardium during a subsequent ischaemic event (like during a myocardial infarction). This important mechanism, called ischaemic pre-conditioning, has been extensively investigated, but the practical ...
Weber, N. C., Schlack, W.
openaire   +3 more sources

Acquired and innate cardioprotection

Journal of Applied Physiology, 2007
with aging of the population, cardiovascular disease is the leading cause of death, disability, and morbidity across continents. In a series of mini-reviews, the Journal of Applied Physiology highlights the most recent advances in molecular and integrative physiology that have provided new ...
Andre, Terzic, Russell L, Moore, Scott A, Waldman   +2 more
openaire   +2 more sources

Phytoestrogens as Cardioprotective Agents

Cardiology in Review, 2005
Epidemiologic studies have shown that women with a higher dietary intake of phytoestrogens, plant-derived compounds with partial estrogen agonist properties, have a lower incidence of cardiovascular disease and breast and uterine cancer than women with a lower dietary intake of these substances.
Denise, Park, Tiffany, Huang, William H, Frishman   +2 more
openaire   +2 more sources