Results 71 to 80 of about 55,383 (254)

Nagapashana Pishti - A Potent Cardio Tonic [PDF]

open access: yes, 2020
Nagapashana (Serpentine), a hydrous silicate of Magnesium (Mg6 (Sio10) OH8), is an important mineral drug used in Ayurveda, often in the form of Pishti (fine powder of Nagapashana). It is a Hrudya Dravya (cardiotonic).
Dr. Chaitra LV   +2 more
core   +3 more sources

Short‐Term Oral Administration of the Porcupine Inhibitor, Wnt‐c59, Improves the Structural and Functional Features of Experimental HFpEF

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
The Porcupine (PORCN) inhibitor, Wnt‐c59, improves diastolic function in experimental heart failure with preserved ejection fraction (HFpEF). ABSTRACT Heart failure with preserved ejection fraction (HFpEF) accounts for approximately 50% of heart failure cases globally, and this incidence is increasing due to extended lifespans and accumulating ...
Mhairi A. Paul   +5 more
wiley   +1 more source

Na/K-ATPase amplification of oxidant stress; a universal but unrecognized clinical target? [PDF]

open access: yes, 2016
The Na/K-ATPase has a signaling function which appears to be separate from its ion pumping function. This signaling function refers to the transduction of conformational changes in the Na/K-ATPase alpha1 subunit into activating Src’s tyrosine kinase ...
Shapiro, MD, Joseph I, Xie, PhD, Zijian
core   +1 more source

Ion pumps as biological targets for decavanadate [PDF]

open access: yes, 2013
The putative applications of poly-, oligo- and mono-oxometalates in biochemistry, biology, pharmacology and medicine are rapidly attracting interest. In particular, these compounds may act as potent ion pump inhibitors and have the potential to play a ...
Aureliano, M.
core   +1 more source

Phytochemical Investigation of an Ostrya carpinifolia L. Extract: An Effective Anti‐Pollution Cosmetic Active Ingredient.

open access: yesChemistry &Biodiversity, Volume 22, Issue 1, January 2025.
Abstract Ostrya carpinifolia L., a member of the Betulaceae family, is a tree endemic to the Mediterranean basin that is well known for the hardness of its wood. In this study, we assess the anti‐pollution activities of a hydroalcoholic extract of O. carpinifolia twigs using several judiciously selected in vitro cosmetic bioassays.
Manon Trinel   +6 more
wiley   +1 more source

A Comparison of Adrenal in Toad-Eating and Nontoad-Eating Snakes [PDF]

open access: yes, 2011
Toads are chemically defended by bufadienolides, a class of cardiotonic steroids lethal to most predators, including many snakes. Bufadienolides bind to Na+K +-ATPase, inhibiting their ability to transport ions.
Mohammadi, Shabnam
core   +2 more sources

Investigation on Anti‐Diarrheal and Antipyretic Activities of citrus maxima Seeds in Swiss Albino Mice Model

open access: yesFood Science &Nutrition, Volume 13, Issue 1, January 2025.
A novel preliminary research work to find out the pharmacological potentials of Citrus maxima seeds on mice model. This research will add a new way towards the discovery of herbal medicine to aid in human life. ABSTRACT In the Rutaceae family Citrus maxima is the biggest among all fruits, tradtionally used for several purposes due to its diverse ...
Nazratun Noor Maria   +4 more
wiley   +1 more source

Vasopressors and Inotropes in Acute Myocardial Infarction Related Cardiogenic Shock: A Systematic Review and Meta-Analysis [PDF]

open access: yes, 2020
Vasopressors and inotropes are routinely used in acute myocardial infarction (AMI) related cardiogenic shock (CS) to improve hemodynamics. We aimed to investigate the effect of routinely used vasopressor and inotropes on mortality in AMI related CS.
D.M. Ouweneel (Dagmar)   +8 more
core   +1 more source

Exploring the Antidiabetic Potential of Pyrimidine‐Derived Chalcones: Synthesis, Biological Evaluation, and Molecular Modeling

open access: yesChemistrySelect, Volume 10, Issue 2, January 15, 2025.
A new series of chalcones (17–43) has been prepared via Claisen Schmidt condensation of newly synthesized pyrimidines (15–16) with aryl aldehydes. The efficient synthesis of these chalcones is confirmed by elemental analysis, mass spectrometry, FTIR, H1‐NMR, and C13‐NMR. These compounds are also screened for anti‐diabetic properties.
Miraj Fatima   +9 more
wiley   +1 more source

Propyl Gallate, a Strong Antioxidant, Increases the Ca2+ Sensitivity of Cardiac Myofilament

open access: yesJournal of Pharmacological Sciences, 2009
Ca2+ sensitizers are cardiotonic agents that directly increase the Ca2+ sensitivity of cardiac myofilament. To find a novel Ca2+ sensitizer, we have screened a group of phenolic compounds by examining their effects on the Ca2+-dependent force generation ...
Naoto Tadano   +5 more
doaj  

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