Results 21 to 30 of about 3,379,973 (255)

Renal Replacement Therapy in CKM: Challenges for Dialytic Therapies and Kidney Transplantation

Cardiorenal Medicine
Cardiovascular-kidney-metabolic (CKM) syndrome integrates the strong interrelationship among cardiovascular disease (CVD), chronic kidney disease (CKD), and metabolic risk factors such as obesity and diabetes.
Mahtab Mashayekhi, Jasjot Bhullar, Zohreh Gholizadeh Ghozloujeh, Sayna Norouzi, Khalil Pathan, Amir Abdipour   +5 more
doaj   +1 more source

Hypoadiponectinemia and the presence of metabolic syndrome in patients with chronic kidney disease: results from the KNOW-CKD study [PDF]

, 2017
BACKGROUND: In patients with chronic kidney disease, metabolic syndrome has been demonstrated to be the culprit behind diverse complications. Adiponectin is known to have anti-atherogenic and cardio-protective effects. Meanwhile, the relationship between
최규헌, 김영리, 유태현, 한승혁   +3 more
core   +1 more source

A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: A Scientific Statement from the American Heart Association.

, 2023
A growing appreciation of the pathophysiological interrelatedness of metabolic risk factors such as obesity and diabetes, chronic kidney disease, and cardiovascular disease has led to the conceptualization of cardiovascular-kidney-metabolic syndrome. The
Virani, Salim S., Neeland, Ian J, Khan, Sadiya S, Carnethon, Mercedes R, Tuttle, Katherine R, Chow, Sheryl L, Coresh, Josef, Baker-Smith, Carissa M, Ndumele, Chiadi E, Mathew, Roy O, Tuttle, Katherine, See all authors in comments,, Ndumele, C   +12 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Mediterranean diet and the metabolic syndrome [PDF]

, 2009
Mediterranean diet and the metabolic syndrome Background: The metabolic syndrome refers to a clustering of risk factors including abdominal obesity, hyperglycaemia, low HDL-cholesterol, hypertriglyceridaemia, and hypertension and it is a risk factor ...
Bos, M.B.
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Cardiovascular-kidney-metabolic syndrome — a new concept of the association of risk factors and metabolic disorders within the cardiovascular and renal continuum. View on the issue

Российский кардиологический журнал
In 2023, the American Heart Association for the first time formally defined cardiovascular-kidney-metabolic (CKM) syndrome as a systemic disease characterized by pathophysiological interactions between metabolic risk factors, chronic kidney disease (CKD),
G. G. Arabidze, M. N. Mamedov
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Exercise rehabilitation in cardiovascular-kidney-metabolic syndrome: a narrative review

Frontiers in Cardiovascular Medicine
Cardiovascular-Kidney-Metabolic Syndrome (CKM) is a multi-organ dysfunction syndrome driven by the interaction of metabolic risk factors, chronic kidney disease, and cardiovascular disease, culminating in adverse cardiovascular events.
Min Sun, Min Sun, Zhou Yang, Shijun Xu, Hongyang Liu   +4 more
doaj   +1 more source