Results 31 to 40 of about 2,663,645 (303)

Association between triglyceride-glucose related indices and all-cause and cardiovascular mortality among the population with cardiovascular-kidney-metabolic syndrome stage 0–3: a cohort study

Cardiovascular Diabetology
Background Cardiovascular-Kidney-Metabolic (CKM) syndrome typically commences with the interaction of insulin resistance (IR), excessive or dysfunctional obesity, and the consequent systemic inflammatory response and oxidative stress.
Peng Zhang, Degang Mo, Wenhua Zeng, Hongyan Dai   +3 more
semanticscholar   +1 more source

Combination of Cardiovascular, Kidney, and Metabolic Diseases in a Syndrome Named Cardiovascular-Kidney-Metabolic, With New Risk Prediction Equations

Kidney International Reports
Associations of chronic kidney disease (CKD) with metabolic syndrome and cardiovascular disease (CVD) have long been recognized. Until recently, such associations were mainly limited to interrelationships between either heart and kidney, heart and ...
Ziad A. Massy, Tilman B. Drueke
doaj   +1 more source

Acute kidney injury and post-reperfusion syndrome in liver transplantation [PDF]

, 2016
In the past decades liver transplantation (LT) has become the treatment of choice for patients with end stage liver disease (ESLD). The chronic shortage of cadaveric organs for transplantation led to the utilization of a greater number of marginal donors
Evison, Felicity, Ferguson, James, Gunson, Bridget, Mitterhofer, Anna Paola, Muiesan, Paolo, Scalera, Irene, Sharif, Adnan, Tinti, Francesca, Umbro, Ilaria   +8 more
core   +3 more sources

Protein-bound uremic toxins as therapeutic targets for cardiovascular, kidney, and metabolic disorders

Frontiers in Endocrinology
Cardiovascular-kidney-metabolic (CKM) syndrome is a systemic clinical condition characterized by pathological and physiological interactions among metabolic abnormalities, chronic kidney disease, and cardiovascular diseases, leading to multi-organ ...
Shihan Zhang, Shasha Tang, Yalei Liu, Binghua Xue, Qinyuan Xie, Lingyun Zhao, Huijuan Yuan   +6 more
doaj   +1 more source

Sex-specific-differences in cardiovascular risk in type-1-diabetes : a cross sectional study [PDF]

, 2013
Background: Little is known about the impact of sex-specific differences in the management of type 1 diabetes (T1DM). Thus, we evaluated the influence of gender on risk factors, complications, clinical care and adherence in patients with T1DM.
Hinstersteiner, Juliane, Johnson, Julienne, Kamyar, Majid Reza, Kautzky, Alexander, Kautzky-Willer, Alexandra, Lemmens-Gruber, Rosa, Saukel, Johannes, Stich, Kathrin   +7 more
core   +1 more source

Aortic pulse wave velocity in children with Cushing syndrome: A window into a marker of early cardiovascular disease. [PDF]

, 2019
ObjectiveTo investigate early signs of cardiovascular arterial remodelling in paediatric patients with Cushing syndrome (CS) in comparison with normative values from healthy children.Study designThe metrics used to assess cardiac health were from ...
Bandettini, Wiphada Patricia, Belyavskaya, Elena, Blain, Hailey, Bluemke, David A, Keil, Margaret, Lodish, Maya, Lodish, Maya, Lyssikatos, Charalampos, Sinaii, Ninet, Stratakis, Constantine, Zeltser, Deena   +10 more
core   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Cardiovascular-kidney-metabolic syndrome — a new concept of the association of risk factors and metabolic disorders within the cardiovascular and renal continuum. View on the issue

Российский кардиологический журнал
In 2023, the American Heart Association for the first time formally defined cardiovascular-kidney-metabolic (CKM) syndrome as a systemic disease characterized by pathophysiological interactions between metabolic risk factors, chronic kidney disease (CKD),
G. G. Arabidze, M. N. Mamedov
doaj   +1 more source

Microvesicles and exosomes: new players in metabolic and cardiovascular disease [PDF]

, 2016
The past decade has witnessed an exponential increase in the number of publications referring to extracellular vesicles (EVs). For many years considered to be extracellular debris, EVs are now seen as novel mediators of endocrine signalling via cell-to ...
Charlotte Lawson, Daniel, Derek M Yellon, Gunduz, Headland, Joop, Jorgensen, Jose M Vicencio, Larson, Lobb, Macey, Mesri, Nomura, Pospichalova, Raturi, Scholz, Sean M Davidson, Ueba, Villarroya-Beltri, Vrijsen, Wang, Welton   +21 more
core   +3 more sources

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source