Prevalence of Cardiovascular–Kidney–Metabolic (CKM) Syndrome in Lithuanian Adults: Insights from a Nationwide Real-World Study Using Electronic Health Records [PDF]
Background and Objectives: Cardiovascular–kidney–metabolic (CKM) syndrome reflects the interconnection between metabolic risk factors, chronic kidney disease (CKD), and cardiovascular disease (CVD).
Gediminas Urbonas +8 more
doaj +3 more sources
Antioxidant Effects of SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic (CKM) Syndrome. [PDF]
The cardiovascular–kidney–metabolic (CKM) syndrome was recently conceptualized to provide a holistic framework for diagnosing and treating the full spectrum of key age-associated interrelated conditions: overweight/obesity, type 2 diabetes mellitus, acute and chronic kidney disease, and cardiovascular disease.
Guerrero-Mauvecin J +8 more
europepmc +3 more sources
Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Case-Based Narrative Review. [PDF]
These 4 hypothetical cases highlight new features of the American Heart Association cardiovascular-kidney-metabolic (CKM) health construct. The cases incorporate the CKM staging system, estimates from the PREVENT risk calculator, and clinical approaches related to CKM stages and individual risk profiles. Topics include management considerations for (1)
Javaid A +8 more
europepmc +4 more sources
Association Between Serum Micronutrients and Advanced CKM Syndrome: An Interpretable Machine Learning-Based Study. [PDF]
ABSTRACT CKM is a common systemic disorder characterized by pathological and physiological interactions between the cardiovascular system. In recent years, the intake of micronutrients has been considered to be associated with CVD, CKD, and other conditions.
Ou Y +9 more
europepmc +3 more sources
Association between dietary inflammatory index score and cardiovascular-kidney-metabolic syndrome: a cross-sectional study based on NHANES [PDF]
BackgroundCardiovascular-kidney-metabolic (CKM) syndrome affects 25% of US adults, with chronic inflammation as a key pathophysiological mechanism. While the inflammatory basis of CKM syndrome is established, associations of the energy-adjusted dietary ...
Huang Yu +4 more
doaj +3 more sources
Dietary antioxidants and mortality in early-stage CKM syndrome: insights from NHANES. [PDF]
PURPOSE: Cardiovascular-kidney-metabolic (CKM) syndrome is a newly recognized multisystem disorder, with over 90% of cases occurring in the early stages (0–3). However, there is a lack of evidence for dietary interventions during this phase. This study is the first to examine the connection between the composite dietary antioxidant index (CDAI) and ...
Duan L +5 more
europepmc +2 more sources
When in doubt, pig it out: a versatile translational platform to study CKD, HFpEF, and CKM syndrome. [PDF]
Chronic kidney disease (CKD), heart failure with preserved ejection fraction (HFpEF), and the recently defined cardiovascular-kidney-metabolic (CKM) syndrome are important challenges for the health care system, associated with a staggering increase in morbidity and mortality rates.
Eirin A, Chade AR.
europepmc +3 more sources
Contemporary and Emerging Therapeutics in Cardiovascular-Kidney-Metabolic (CKM) Syndrome: In Memory of Professor Akira Endo. [PDF]
Cardiovascular-kidney-metabolic (CKM) syndrome is a multifaceted, systemic disorder characterized by the interplay of cardiovascular disease (CVD), chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), and obesity. This review synthesizes current and emerging therapeutic strategies aimed at addressing the shared pathophysiologic mechanisms ...
Bharaj IS +12 more
europepmc +3 more sources
Cardiovascular–Kidney–Metabolic (CKM) Syndrome as Independent Risk Factor for Pneumococcal Pneumonia: Evidence from a Territory-Wide Study [PDF]
Cardiovascular–kidney–metabolic (CKM) syndrome is an increasingly recognized condition that highlights the interaction between three important medical co-morbidities.
Wang Chun Kwok +7 more
doaj +2 more sources
Improvement of Kidney Function Following Unilateral Nephrectomy in a Patient With Cardiovascular-Kidney-Metabolic (CKM) Syndrome. [PDF]
Cardiovascular-kidney-metabolic (CKM) syndrome is a significant contributor to the progressive decline in renal function, often leading to advanced chronic kidney disease. We report a 55-year-old man with a history of obesity, diabetes, and hypertension who was diagnosed with renal cell carcinoma (RCC) and underwent unilateral nephrectomy for his ...
Asopa M +5 more
europepmc +2 more sources

