Exercise in CKM syndrome progression: a stage-specific approach to cardiovascular, metabolic, and renal health. [PDF]
Abstract Cardiovascular-Kidney-Metabolic (CKM) syndrome progresses through distinct stages, from early metabolic risk factors to advanced cardiovascular disease and kidney dysfunction. Across these stages, exercise remains a central yet underutilized intervention, offering physiological adaptations that address metabolic dysregulation,
Papadakis Z.
europepmc +5 more sources
When in doubt, pig it out: a versatile translational platform to study CKD, HFpEF, and CKM syndrome. [PDF]
Chronic kidney disease (CKD), heart failure with preserved ejection fraction (HFpEF), and the recently defined cardiovascular-kidney-metabolic (CKM) syndrome are important challenges for the health care system, associated with a staggering increase in morbidity and mortality rates.
Eirin A, Chade AR.
europepmc +4 more sources
Background Chronic obstructive pulmonary disease (COPD) and cardiovascular-kidney-metabolic (CKM) syndrome are major public health concerns, yet their interrelationship remains under-explored.
Jisong Yan +9 more
doaj +5 more sources
Association Between Serum Micronutrients and Advanced CKM Syndrome: An Interpretable Machine Learning‐Based Study [PDF]
ABSTRACT CKM is a common systemic disorder characterized by pathological and physiological interactions between the cardiovascular system. In recent years, the intake of micronutrients has been considered to be associated with CVD, CKD, and other conditions.
Yi Ou, Xinyi Shao, Yuan Zhan
exaly +5 more sources
Contemporary and Emerging Therapeutics in Cardiovascular-Kidney-Metabolic (CKM) Syndrome: In Memory of Professor Akira Endo. [PDF]
Cardiovascular-kidney-metabolic (CKM) syndrome is a multifaceted, systemic disorder characterized by the interplay of cardiovascular disease (CVD), chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), and obesity. This review synthesizes current and emerging therapeutic strategies aimed at addressing the shared pathophysiologic mechanisms ...
Bharaj IS +12 more
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Vitamin D deficiency, multimorbidity, and mortality in stage 2 cardiovascular-kidney-metabolic (CKM) Syndrome: evidence from the NHANES 2001-2018 cohort. [PDF]
Ziqiu W +6 more
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Glucocorticoid resistance-induced inflammation drives cardiovascular-kidney-metabolic (CKM) syndrome pathophysiology. [PDF]
Martinez GJ, Stec DE, Hinds TD.
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Association of Body Roundness Index with all-cause and cardiovascular mortality in patients with cardiovascular-kidney-metabolic (CKM) syndrome stages 0-3: a cohort study. [PDF]
He Z +7 more
europepmc +2 more sources
Mediating effect of insulin resistance in the relationship between dietary inflammatory index and cardiovascular–kidney–metabolic syndrome stage in US adults, 2007–2018 [PDF]
Background: Cardiovascular–kidney–metabolic (CKM) syndrome is a progressive, five-stage disease framework driven by interrelated cardiovascular, renal, and metabolic dysfunction, with chronic inflammation and insulin resistance (IR) playing key roles ...
Ying Xiao +12 more
doaj +2 more sources
Relationship between moderate alcohol consumption and all-cause mortality across different stages of Cardiovascular-Kidney-Metabolic (CKM) Syndrome: a cohort study [PDF]
Aomiao Chen, Jintao Lin, Zongji Zheng
exaly +2 more sources

