The cardiovascular kidney metabolic (CKM) syndrome is a dynamic geriatric condition that has received limited research attention regarding its potential associations with the triglyceride glucose (TyG) index.
Lanlan Wu, Zheng Huang
doaj +2 more sources
Association between triglyceride glucose body mass index and 1 year all cause mortality in stage 4 CKM syndrome patients. [PDF]
The triglyceride-glucose body mass index (TyG-BMI) is acknowledged as a dependable surrogate biomarker for the evaluation of insulin resistance (IR). Current research indicates a significant correlation between TyG-BMI and the risk of subsequent cardiovascular events in individuals diagnosed with cardiovascular-kidney-metabolic syndrome (CKM) at stages
Pan W +5 more
europepmc +4 more sources
Cardiovascular-Kidney-Metabolic Syndrome: An Update for Clinician [PDF]
Cardiovascular-kidney-metabolic (CKM) syndrome is a systemic abnormality resulting from complex pathophysiological interactions among cardiovascular disease, chronic kidney disease, and metabolic risk factors, particularly diabetes mellitus and obesity ...
Muhammad Yamin, Harits Adi Putra
doaj +3 more sources
Protein-bound uremic toxins as therapeutic targets for cardiovascular, kidney, and metabolic disorders [PDF]
Cardiovascular-kidney-metabolic (CKM) syndrome is a systemic clinical condition characterized by pathological and physiological interactions among metabolic abnormalities, chronic kidney disease, and cardiovascular diseases, leading to multi-organ ...
Shihan Zhang +6 more
doaj +3 more sources
Association Between Serum Advanced Glycation End Products and Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A 3-Year Longitudinal Cohort Study (2019-2022). [PDF]
ABSTRACTBackgroundCardiovascular‐kidney‐metabolic (CKM) syndrome begins with obesity and glucose abnormalities, advancing to cardiovascular and kidney complications. This study investigates the relationship of advanced glycation end products (AGEs) with CKM syndrome staging and transition patterns.MethodsThis 3‐year longitudinal study (2019–2022) of ...
Zhao H +16 more
europepmc +3 more sources
Bilirubin bioconversion to urobilin in the gut-liver-kidney axis: A biomarker for insulin resistance in the Cardiovascular-Kidney-Metabolic (CKM) Syndrome. [PDF]
The rising rates of obesity worldwide have increased the incidence of cardiovascular disease (CVD), making it the number one cause of death. Higher plasma bilirubin levels have been shown to prevent metabolic dysfunction and CVD. However, reducing levels leads to deleterious outcomes, possibly due to reduced bilirubin half-life that escalates the ...
Kipp ZA +4 more
europepmc +3 more sources
Role of Residual Inflammation as a Risk Factor Across Cardiovascular-Kidney-Metabolic (CKM) Syndrome: Unpacking the Burden in People with Type 2 Diabetes. [PDF]
Type 2 diabetes mellitus (T2DM) is a global health crisis, with cardiovascular disease (CVD) accounting for 75% of mortality in this population. Despite advances in managing traditional risk factors, such as low-density lipoprotein cholesterol (LDL) cholesterol reduction (IMPROVE-IT, FOURIER), antithrombotic therapies (PEGASUS, COMPASS), and ...
Ghafoury R +3 more
europepmc +3 more sources
Exercise rehabilitation in cardiovascular-kidney-metabolic syndrome: a narrative review [PDF]
Cardiovascular-Kidney-Metabolic Syndrome (CKM) is a multi-organ dysfunction syndrome driven by the interaction of metabolic risk factors, chronic kidney disease, and cardiovascular disease, culminating in adverse cardiovascular events.
Min Sun +4 more
doaj +2 more sources
Prevalence and mortality of cardiovascular-kidney-metabolic syndrome in US adults, 1999–2018 [PDF]
Background: Cardiovascular-kidney-metabolic (CKM) syndrome is a novel staging construct that reflects the pathophysiological interplay between these individual conditions.
Huzaifa Ahmad Cheema +8 more
doaj +2 more sources
Background Chronic obstructive pulmonary disease (COPD) and cardiovascular-kidney-metabolic (CKM) syndrome are major public health concerns, yet their interrelationship remains under-explored.
Jisong Yan +9 more
doaj +2 more sources

