Abstract Background The health effects of moderate alcohol consumption remain inconclusive, both in the general population and among individuals with specific diseases. Cardiovascular-Kidney-Metabolic Syndrome (CKM) is a novel concept that involves various health conditions.
Zhuotong Wang +11 more
openaire +3 more sources
Cardiovascular-kidney-metabolic (CKM) syndrome is associated with increased mortality in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD). [PDF]
Chen Q +15 more
europepmc +2 more sources
A Comprehensive Analysis of the Impact of Nutrient Intakes on the Stages and Mortality of Cardiovascular-Kidney-Metabolic Syndrome. [PDF]
Higher sodium and lower potassium intake were linked to advanced CKM syndrome stages, while specific nutrients influenced mortality risk and were incorporated into a predictive nomogram. ABSTRACT Cardiovascular–kidney–metabolic (CKM) syndrome remains highly prevalent worldwide and is associated with substantial mortality.
Qing J +6 more
europepmc +2 more sources
DEC2 modulates orexin expression and regulates sleep. [PDF]
Adequate sleep is essential for physical and mental health. We previously identified a missense mutation in the human DEC2 gene (BHLHE41) leading to the familial natural short sleep behavioral trait.
Fu, Ying-Hui +7 more
core +1 more source
Quality of life with conservative care compared with assisted peritoneal dialysis and haemodialysis [PDF]
Background. There is little information about quality of life (QoL) for patients with end-stage kidney disease (ESKD) choosing conservative kidney management (CKM).
Barendse +26 more
core +4 more sources
Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria [PDF]
Systemic inflammation and sequestration of parasitized erythrocytes are central processes in the pathophysiology of severe Plasmodium falciparum childhood malaria. However, it is still not understood why some children are more at risks to develop malaria
Afolabi, Nathaniel K. +19 more
core +3 more sources
Trithorax group proteins: switching genes on and keeping them active [PDF]
Cellular memory is provided by two counteracting groups of chromatin proteins termed Trithorax group (TrxG) and Polycomb group (PcG) proteins. TrxG proteins activate transcription and are perhaps best known because of the involvement of the TrxG protein ...
Cavalli, G. +3 more
core +1 more source
HIC2 regulates isoform switching during maturation of the cardiovascular system. [PDF]
Physiological changes during embryonic development are associated with changes in the isoform expression of both myocyte sarcomeric proteins and of erythrocyte haemoglobins. Cell type-specific isoform expression of these genes also occurs. Although these
Dykes, IM, Scambler, PJ, van Bueren, KL
core +4 more sources
Whole genome sequence and analysis of the Marwari horse breed and its genetic origin [PDF]
Background: The horse (Equus ferus caballus) is one of the earliest domesticated species and has played an important role in the development of human societies over the past 5,000 years.
Bhak, Jong Hwa +12 more
core +1 more source
Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post-genome era. [PDF]
The horse reference genome from the Thoroughbred mare Twilight has been available for a decade and, together with advances in genomics technologies, has led to unparalleled developments in equine genomics.
Bellone, R +3 more
core +2 more sources

