Results 171 to 180 of about 3,440,112 (288)

Associations of Cardiovascular-Kidney-Metabolic Syndrome With All-Cause and Cardiovascular Death and the Progression of Cardiovascular-Kidney-Metabolic Syndrome Among Hong Kong Chinese People Over 2 Decades. [PDF]

J Am Heart Assoc
Li L, Lui DT, Fong CH, Mak JH, Cheung CY, Xu A, Tan KC, Tse HF, Woo J, Lam TH, Woo YC, Cheung BM, Lam KS, Lee CH.   +13 more
europepmc   +1 more source

Stage‐Dependent Prognostic Value of the Joint MASLD–NAFLD Fibrosis Score Phenotype Across the Cardiovascular–Kidney–Metabolic Syndrome Continuum: A Retrospective NHANES Cohort Analysis, 1999–2018

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The cardiovascular–kidney–metabolic (CKM) framework and metabolic dysfunction–associated steatotic liver disease (MASLD) describe a shared clinical continuum, but the prognostic value of joint fatty liver index (FLI)–NAFLD fibrosis score (NFS) phenotypes across CKM stages is uncertain.
Yi‐Fei Wang, Jian‐Li Zhang, Yun‐Fei Wang, Jun‐Peng Xiong, Rong‐Hui Yu, Ze‐Ping Hu   +5 more
wiley   +1 more source

Butyrate and Butyrate-Producing Bacteria in Cardiovascular-Kidney-Metabolic Syndrome. [PDF]

Antioxidants (Basel)
Huang W, Zhou F, Wang S, Shu M, Liu Z, Gao L.   +5 more
europepmc   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Cardiovascular-Kidney-Metabolic Syndrome and Health Risk Behaviors in U.S. Adults. [PDF]

AJPM Focus
Sharma M, Chudasama D, Datta BK, Coughlin SS, Vernon MM, Sullivan JC.   +5 more
europepmc   +1 more source

Prevention of Early Onset of Breast Cancer With Ashwagandha

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm, Su‐Hyeong Kim, Shivendra V. Singh   +2 more
wiley   +1 more source

Cardiovascular-Kidney-Metabolic Syndrome Severity and Risk of Pancreatic Cancer in a Large Prospective Cohort. [PDF]

Diabetes Metab Res Rev
Choi M, Heo SJ, Kwon YJ, Kang CM.
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Metabolomic Profiling Delineates Stage-Associated Metabolic Remodelling in Cardiovascular-Kidney-Metabolic Syndrome. [PDF]

Diabetes Metab Res Rev
Gong X, Li C, Chen J, Wang Y, Tang W, Zhang X, Yin J, Zhao X, Yu H, Fu P, Zeng X.   +10 more
europepmc   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source