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A Synopsis of the Evidence for the Science and Clinical Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Scientific Statement From the American Heart Association

open access: yesCirculation, 2023
A growing appreciation of the pathophysiological interrelatedness of metabolic risk factors such as obesity and diabetes, chronic kidney disease, and cardiovascular disease has led to the conceptualization of cardiovascular-kidney-metabolic syndrome. The
Walter Kernan, Sonali S Patel
exaly   +2 more sources

Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association

open access: yesCirculation, 2023
Cardiovascular-kidney-metabolic health reflects the interplay among metabolic risk factors, chronic kidney disease, and the cardiovascular system and has profound impacts on morbidity and mortality.
Walter Kernan, Sonali S Patel
exaly   +2 more sources

Cardiovascular-Kidney-Metabolic Syndrome

Cardiology Clinics
Cardiovascular–Kidney–Metabolic (CKM) syndrome describes an integrated pathophysiological continuum characterized by the coexistence of metabolic dysfunction, renal impairment, and cardiovascular disease. Recognizing CKM syndrome at an early stage is vital, as the combined effects of these interrelated disorders significantly worsen patient outcomes ...
Silvi, Shah, Janani, Rangaswami
  +6 more sources

Epidemiology of cardiovascular–kidney–metabolic syndrome

Nature Reviews Nephrology
Cardiovascular-kidney-metabolic (CKM) syndrome, defined by the American Heart Association in 2023, describes the interconnected risks of metabolic dysfunction, chronic kidney disease and cardiovascular disease. By unifying these conditions, CKM highlights shared pathophysiology, overlapping risk factors and common therapeutic approaches.
Lucas A. Mavromatis, Morgan E. Grams
openaire   +2 more sources

The therapeutic approach to cardiovascular–kidney–metabolic syndrome

Nature Reviews Nephrology
Obesity, type 2 diabetes mellitus and chronic kidney disease (CKD) are highly prevalent conditions that frequently coexist and result in an excess burden of cardiovascular disease (CVD), premature death and health-care resource utilization. The concept of cardiovascular-kidney-metabolic (CKM) syndrome highlights the overlap of pathophysiological ...
Janani Rangaswami   +2 more
openaire   +2 more sources

Cardiovascular-kidney-metabolic syndrome – An integrative review

Progress in Cardiovascular Diseases
The American Heart Association recently defined the complex interactions among the cardiovascular, renal, and metabolic systems as CKM syndrome. To promote better patient outcomes, having a more profound understanding of CKM pathophysiology and pursuing holistic preventative and therapy strategies is critical.
Katiana Simões, Kittelson   +3 more
openaire   +2 more sources

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