Results 241 to 250 of about 3,242,366 (329)

Visceral adiposity and cardiovascular risk in the era of cardiovascular-kidney-metabolic syndrome. [PDF]

Am J Prev Cardiol
Kokkorakis M, Oikonomou EK.
europepmc   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Comment on: "Association of Frailty and Its Trajectories With the Risk of Cardiovascular-Kidney-Metabolic Syndrome Progression: A Longitudinal Cohort Study". [PDF]

Geriatr Gerontol Int
Zhao S, Du Y.
europepmc   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Optimizing Care in Cardiovascular-Kidney-Metabolic Syndrome: Registry Data From the Cardiometabolic Center Alliance. [PDF]

Circ Popul Health Outcomes
Neeland IJ, Magwire ML, Kwun A, Aistrope DS, Andaya EAK, Bashall A, Benziger CP, De Albuquerque Rocha N, Butler J, Davis L, Denicola D, Eckel RH, Gosch K, Harness L, Helms AR, Iluyomade A, Miller KA, Gianos E, Donahoe S, Patel S, Plutzky J, Stafos A, Sauer AJ, Rajagopalan S, Kosiborod MN.   +24 more
europepmc   +1 more source

Bell's Palsy in 11,255 Cases: Cardiometabolic Associations in a Population‐Based Healthcare Database

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To estimate Bell's palsy incidence and evaluate the prevalence and associations with diabetes and other cardiometabolic conditions. Study Design Population‐based cohort study. Setting Clalit Health Services, the largest healthcare provider organization in Israel (2005‐2022).
Tomer Boldes, Ori Cohen Michael, Ortal Fallek Boldes, Firas Kassem, Benny Nageris, Ameen Biadsee   +5 more
wiley   +1 more source

Association Between Time in Range and Advanced Cardiovascular-Kidney-Metabolic Syndrome in Older Adults With Type 2 Diabetes. [PDF]

Diabetes Obes Metab
Su H, Ni J, Cai J, Zhu W, Wang Y, Zhou J, Lu J, Ma X.   +7 more
europepmc   +1 more source

Cytogenetic and Molecular Findings in Hydrops‐Related Mirror Syndrome

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Mirror syndrome is a rare, life‐threatening condition in which maternal fluid overload mirrors fetal hydrops. Data on genetic findings in affected pregnancies are limited. We compared genetic diagnoses in hydrops cases with and without mirror syndrome.
Brian A. Burnett, Christian M. Parobek, Jessian L. Munoz, Lauren E. Westerfield, Kristi Poling, Cara Buskmiller, Amir A. Shamshirsaz, Roopali V. Donepudi, Ignatia B. Van den Veyver, Magdalena Sanz Cortes, Michael A. Belfort, Ahmed A. Nassr   +11 more
wiley   +1 more source

Associations of dietary inflammatory and antioxidant indices with mortality in adults with cardiovascular-kidney-metabolic syndrome: A mediation analysis. [PDF]

Medicine (Baltimore)
Li Y, Kang J.
europepmc   +1 more source

Clinical interpretation of cardiac troponin in athletes: From endurance exercise to exertional injury

PM&R, EarlyView.
Abstract Exertional heat illness (EHI) and exertional rhabdomyolysis (ER) are increasingly recognized causes of morbidity in competitive and tactical athletes. Cardiac troponin (cTn) elevation, traditionally viewed as a marker of myocardial necrosis, may also be seen in these settings and can create significant diagnostic and prognostic uncertainty ...
John‐Henry L. Dean, Jeffrey C. Leggit, M. Alaric Franzos   +2 more
wiley   +1 more source