Results 41 to 50 of about 3,242,366 (329)

A Bivariate Genome-Wide Approach to Metabolic Syndrome STAMPEED Consortium [PDF]

, 2010
OBJECTIVE The metabolic syndrome (MetS) is defined as concomitant disorders of lipid and glucose metabolism, central obesity, and high blood pressure, with an increased risk of type 2 diabetes and cardiovascular disease.
O'Reilly, Paul F., David J. Couper, Marjo-Riitta Jarvelin, Mathias, Rasika A., Sun, Y. V., Becker, DM, Zhang, Q., Psaty, Bruce M., Dhananjay Vaidya, Assimes, Themistocles L., Rotter, Jerome I, Cashell Jaquish, Becker, LC, McCarthy, Mark I, Boerwinkle, E., Franceschini, Nora, O'Reilly, P. F., O'Reilly, Paul F, Feitosa, MF, Hartikainen, A.-L., Yanek, L., Knowles, JW, Bruce M. Psaty, Becker, Diane M, Mathias, RA, Lewis C. Becker, Goodarzi, Mark O., Kardia, Sharon LR, Glazer, NL, Themistocles L. Assimes, Kraja, Aldi T, Couper, D. J., Mathias, Rasika A, Couper, DJ, Kardia, SL, Kullo, I. J., Rasika A. Mathias, Province, Michael A., Guo Li, Borecki, IB, Absher, Devin, Borecki, Ingrid B., Chakravarti, A, Iribarren, C., Yanek, Lisa, Kari E. North, Jaquish, Cashell, O’Reilly, Paul F, Sovio, U., Becker, D. M., Sun, Yan V, Kraja, AT, Paul F. O’Reilly, Yii-Der Ida Chen, Lisa Yanek, Vaidya, D., Quertermous, Thomas, Chen, Yii-Der Ida, Leena Palotie, Sun, Yan V., Boerwinkle, Eric, Aldi T. Kraja, Goodarzi, Mark O, Pankow, JS, Talin Haritunians, Psaty, Bruce M, Palotie, L., Boerwinkle, E, Zhang, Q, Becker, L. C., Kral, Brian, Sovio, U, Feitosa, Mary F., Haritunians, T., North, Kari E., Haritunians, Talin, Brian Kral, Quertermous, T., Chen, Y.-d. I., Hartikainen, Anna-Liisa, Feitosa, Mary F, Chakravarti, A., Jarvelin, Marjo-Riitta, Hartikainen, AL, Mark O. Goodarzi, Diane M. Becker, Chakravarti, Aravinda, Sharon L.R. Kardia, Mary F. Feitosa, Palotie, L, Couper, David J., Anna-Liisa Hartikainen, Borecki, I. B., Nora Franceschini, Jarvelin, MR, North, Kari E, Knowles, Joshua W, Pankow, James S, Jerome I. Rotter, Couper, David J, Franceschini, N., McCarthy, M. I., Iribarren, C, Psaty, BM, Yanek, L, Vaidya, Dhananjay, Psaty, B. M., Kral, B, Becker, Lewis C, Kral, B., Michael A. Province, Ingrid B. Borecki, Chen, YD, Goodarzi, M. O., Glazer, N. L., Becker, Lewis C., Palotie, Leena, Jaquish, C., Kraja, Aldi T., Glazer, Nicole L, Kullo, IJ, Thomas Quertermous, Kullo, Iftikhar J, Joshua W. Knowles, Carlos Iribarren, Zhang, Qunyuan, Quertermous, T, Ulla Sovio, Li, Guo, Haritunians, T, Mathias, R. A., Jarvelin, M.-r., Sovio, Ulla, Qunyuan Zhang, Iftikhar J. Kullo, Province, Michael A, Rotter, J. I., Pankow, James S., Province, MA, McCarthy, MI, James S. Pankow, Knowles, J. W., Borecki, Ingrid B, Li, G, Eric Boerwinkle, Becker, Diane M., Kardia, Sharon L. R., Glazer, Nicole L., O'Reilly, PF, Sun, YV, North, K. E., Li, G., Mark I. McCarthy, Absher, D, Iribarren, Carlos, Vaidya, D, Absher, D., Feitosa, M. F., Franceschini, N, Aravinda Chakravarti, Knowles, Joshua W., Assimes, Themistocles L, Yan V. Sun, Kardia, S. L. R., Pankow, J. S., Rotter, Jerome I., Assimes, TL, Devin Absher, McCarthy, Mark I., North, KE, Assimes, T. L., Goodarzi, MO, Province, M. A., Jaquish, C, Nicole L. Glazer, Rotter, JI, Kraja, A. T., Kullo, Iftikhar J.   +177 more
core   +1 more source

Protein-bound uremic toxins as therapeutic targets for cardiovascular, kidney, and metabolic disorders

Frontiers in Endocrinology
Cardiovascular-kidney-metabolic (CKM) syndrome is a systemic clinical condition characterized by pathological and physiological interactions among metabolic abnormalities, chronic kidney disease, and cardiovascular diseases, leading to multi-organ ...
Shihan Zhang, Shasha Tang, Yalei Liu, Binghua Xue, Qinyuan Xie, Lingyun Zhao, Huijuan Yuan   +6 more
doaj   +1 more source

Prevalence of the Cardiovascular-Kidney-Metabolic Syndrome in 3 Chinese Cohorts

JACC Asia
Xianghai Zhou, Yufeng Li, Xiantong Zou   +2 more
exaly   +4 more sources

Association of novel triglyceride-glucose-related indices with incident stroke in early-stage cardiovascular-kidney-metabolic syndrome

Cardiovascular Diabetology
Emerging triglyceride-glucose (TyG)-related indices, such as the TyG-related body roundness index (TyG-BRI), a body shape index (TyG-ABSI), weight-adjusted waist index (TyG-WWI), and Chinese visceral adiposity index (TyG-CVAI), have gained attention as ...
Yong Yue, Pengcheng Li, Zhengyu Sun, Rumi Murayama, Zongping Li, K. Hashimoto, Ye Zhang   +6 more
semanticscholar   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Prevalence of metabolic syndrome in patients with psoriasis: a population-based study in the United Kingdom. [PDF]

, 2012
Increasing epidemiological evidence suggests independent associations between psoriasis and cardiovascular and metabolic disease. Our objective was to test the hypothesis that directly assessed psoriasis severity relates to the prevalence of metabolic ...
Troxel, Andrea B, Nehal N. Mehta, Gelfand, Joel M, Margolis, David J., Shin, Daniel B, Seminara, Nicole M, Mehta, Nehal N., Langan, Sinéad M, Kimmel, Stephen E., Mehta, Nehal N, Seminara, Nicole M., Stephen E. Kimmel, Nicole M. Seminara, Gelfand, Joel M., Troxel, Andrea B., Andrea B. Troxel, Sinéad M. Langan, Shin, Daniel B., Kimmel, Stephen E, Margolis, David J, Langan, Sinéad M., Joel M. Gelfand, David J. Margolis, Daniel B. Shin   +23 more
core   +1 more source

Association between atherogenic index of plasma and future risk of cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide prospective cohort study

Cardiovascular Diabetology
As an emerging concept, Cardiovascular-kidney-metabolic syndrome (CKM) elucidates the intricate interconnection between metabolic disorders(Mets), cardiovascular disease(CVD), and chronic kidney disease(CKD).
Gaoshu Zheng, Ji-Jie Jin, Fei Wang, Qianrong Zheng, Jiaxin Shao, Jiangnan Yao, Pan Huang, Hao Zhou, Jiang-Hua Zhou   +8 more
semanticscholar   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Lipid accumulation product and visceral adiposity index: two indices to predict metabolic syndrome and insulin resistance in chronic kidney disease patients

Endocrine Regulations, 2023
Objective. Chronic kidney disease (CKD), metabolic syndrome (MetS) and insulin resistance (IR) are the major health problems associated with the increasing risk of cardiovascular and cerebrovascular complications.
Fahmy Ahmed Mohamed, El Shall Nelly, Kabbash Ibrahim, El Ahwal Loai, Selim Amal   +4 more
doaj   +1 more source