Results 41 to 50 of about 1,734,591 (243)
FEBS Open Bio, EarlyView.We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang +7 more
wiley +1 more source
Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan +7 more
wiley +1 more source
Scientific Reports, 2020 Machine learning approaches using intravascular optical coherence tomography (OCT) to predict fractional flow reserve (FFR) have not been investigated.
Jung-Joon Cha +10 more
doaj +1 more source
Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita +7 more
wiley +1 more source
Dynamic simulation of aortic valve stenosis using a lumped parameter cardiovascular system model with flow regime dependent valve pressure loss characteristics [PDF]
arXiv, 2022 Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and obstructive lesions on the valve body can assist clinicians in preparing personalised treatments.
arxiv
Indian Pacing and Electrophysiology Journal, 2020 Introduction: Epicardial exit sites of ventricular tachycardia (VT) are frequently encountered during VT ablation requiring an epicardial ablation approach for successful elimination of VT.
Darshan Krishnappa +7 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sleep spindles are an electrophysiological fingerprint of the sleeping human brain. They can be described in terms of duration, frequency, amplitude, and density, and vary widely according to age and sex. Spindles play a role in sleep and wake functions and are altered in several neurological and psychiatric disorders.
Julien Coelho +8 more
wiley +1 more source
Impact of atrial fibrillation on the cardiovascular system through a lumped-parameter approach [PDF]
, 2014 Atrial fibrillation (AF) is the most common arrhythmia affecting millions of people in the Western countries and, due to the widespread impact on the population and its medical relevance, is largely investigated in both clinical and bioengineering sciences. However, some important feedback mechanisms are still not clearly established. The present study
arxiv +1 more source
iCardo: A Machine Learning Based Smart Healthcare Framework for Cardiovascular Disease Prediction [PDF]
arXiv, 2022 The point of care services and medication have become simpler with efficient consumer electronics devices in a smart healthcare system. Cardiovascular disease is a critical illness which causes heart failure, and early and prompt identification can lessen damage and prevent premature mortality.
arxiv
Arthritis Care &Research, EarlyView.Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner +12 more
wiley +1 more source