Results 71 to 80 of about 3,282 (271)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Life After Graduation : A Systematic Literature Review of Life Design Career Counseling for High School Students

open access: yesJurnal Studi Guru dan Pembelajaran
The challenges of globalization, rapid technological advancement, and dynamic job markets have increased the urgency of career planning among high school students.
Salma Nurul Baidho, Sinta Saraswati
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Future work selves : how salient hoped-for identities motivate proactive career behaviors [PDF]

open access: yes, 2012
The term future work self refers to an individual's representation of himself or herself in the future that reflects his or her hopes and aspirations in relation to work.
Griffin, Mark A.   +5 more
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

My Career Story [PDF]

open access: yes, 2017
My career story (MCS) comprises a self-guided autobiographical workbook designed to simulate career construction counseling. The MCS contains a series of questions from the Career Construction Interview to elicit a life-career story and reveal a life ...
Hartung, P. J.   +3 more
core   +1 more source

School Counseling and Guidance Programs: Examination of Career Adaptabilities [PDF]

open access: yes, 2020
The role of school counseling has become prominent in supporting the youth for their future career and the business world, according to the requirements of 21st century and its emerging challenges such as Industry 4.0.
Karacan-Özdemir, Nurten   +2 more
core   +1 more source

CAREER COUNSELLING: A CONSTRUCTIVE INTERACTION BETWEEN SCIENCE AND PRACTICE

open access: yesПрофесійна педагогіка, 2019
The article analyzes the current status of student counselling in vocational education institutions, contextualizes findings on this problem and discloses contradictory points of counselling. It is justified that vocational education institutions normally view professional career counselling as the processes of dealing with and solving students ...
Liudmyla Bazyl, Valerii Orlov
openaire   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy