Results 61 to 70 of about 4,044,828 (274)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Whole-life career management: A counseling intervention framework [PDF]
, 2020 It is widely recognized that career management and counseling require a consideration of work and nonwork roles. I present a career counseling intervention framework to help clients self-direct their careers and attain work-nonwork balance.
Andreas Hirschi, Hirschi, Andreas
core +3 more sources
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Behavioral SciencesAdolescent students’ meaning in life is an important topic of research in positive psychology and educational psychology. Meaning in life is of outstanding value to the whole career development of Chinese higher vocational college students (CHVCS), and ...
Huadi Wang +4 more
doaj +1 more source
Career Counseling Interventions for Video Game Players
, 2018 Video games are becoming ubiquitous in Western societies. However, this virtual leisure has received little attention from researchers in career counseling, leaving career counselors relatively unprepared to work with video game players. In this article,
Armengol, Jérôme, Rochat, Shékina
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Journal of Research in Education Sciences, 2010 本研究旨在發現高中學生不同的「生涯發展組型」（career development patterns, CDP），進而對CDP 進行效度考驗，並探析其在升學及生涯輔導上的意義。本研究分三部分：一、組型建構：採取量化取向之調查法，根據20 所高中1,443 名學生在「工作價值觀量表」、「生涯探索量表」與「多元智能量表」上的評量結果，加上學科能力測驗（五科）成績，以總共三十種變項進行因素分析和典型相關分析，綜合研判組合成為八種有意義的CDP，包括實用組型、研究組型、藝術組型、社會組型、企業組型、事務組型 ...
吳武典 Wu-Tien Wu +6 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
CAREER COUNSELLING: A CONSTRUCTIVE INTERACTION BETWEEN SCIENCE AND PRACTICE
Професійна педагогіка, 2019 The article analyzes the current status of student counselling in vocational education institutions, contextualizes findings on this problem and discloses contradictory points of counselling. It is justified that vocational education institutions normally view professional career counselling as the processes of dealing with and solving students ...
Liudmyla Bazyl, Valerii Orlov
openaire +2 more sources
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source