Results 101 to 110 of about 1,985,934 (292)
Career readiness for all [PDF]
, 2019 The goal of the Coalition for Career Development is to make career readiness the first priority of American education. Our vision is to ensure that ALL students secure productive employment in their chosen pathway as efficiently and cost-effectively as ...
Bray, Jan +4 more
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Best of Both Worlds: Management Controls in a Business Process Outsourcing (BPO) Organisation in the Post-Pandemic Hybrid Era [PDF]
Colombo Business JournalThis research explores management control systems (MCSs) in the post-pandemic hybrid work era and how different controls are used to facilitate managerial intentions, drawing empirical evidence from a Business Process Outsourcing (BPO) firm.
Semini P. Gunasekera +1 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Future InternetMeeting global forest restoration targets by 2030 requires a transition from labor-intensive and opaque practices to scalable, intelligent, and verifiable systems.
Nophea Sasaki, Issei Abe
doaj +1 more source
Integrated policies: creating systems that work [PDF]
, 2015 This paper is concerned with the integration of career development policies across the world. It was prepared in advance of the International Centre for Career Development and Public Policy symposium in Des Moines 2015.Kuder and the International Centre ...
Hooley, Tristram, McCarthy, John
core +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
, 2015 In this article we provide a brief update on some of the research papers and reports published in 2014 on career development, examining in particular some issues related to equality and employment, career adaptability and self-efficacy in career decision
Mieschbuehler, Ruth, Vickers, Rob
core +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source