Results 111 to 120 of about 1,993,959 (343)
Student Learning Plans: Supporting Every Student's Transition to College and Career [PDF]
, 2011 Student learning plans (SLPs) represent an emerging practice in how public schools across the country are supporting the development of students' college and career readiness skills.
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
, 2015 In this article we provide a brief update on some of the research papers and reports published in 2014 on career development, examining in particular some issues related to equality and employment, career adaptability and self-efficacy in career decision
Mieschbuehler, Ruth, Vickers, Rob
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Application of Immersive Virtual Reality in the Training of Future Teachers: Scope and Challenges
Virtual WorldsIntroduction: The integration of Immersive Virtual Reality (IVR) into teacher education is a significant innovation that can enhance the learning and practical training of future teachers.
Carlos Arriagada-Hernández +4 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Psychiatry and Clinical PsychopharmacologyBackground: To explore the mediating effect of smartphone addiction between psychological resilience and insomnia among university students. Methods: This study included 581 clinical medical students from the Dalian Medical University, enrolled ...
Fan Li
doaj +1 more source
A workforce development strategy for the Adult Career Information, Advice and Guidance workforce in England [PDF]
, 2010 This paper outlines Lifelong Learning UK’s approach to the development of a Workforce Development Strategy for the adult career information, advice and guidance workforce in England.
Jackson, Heather, Neary, Siobhan
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Development and validation of career sustainability scale for mid-career employees
Frontiers in PsychologyA sustainability perspective on careers builds a resilient career system by simultaneously considering individual’s current career needs and long-term career outcomes.
Suyeon Kim, Heesu Lee, Sungmi Jin
doaj +1 more source