Results 81 to 90 of about 1,985,934 (292)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

What do you want to be? Lower-Income Women Face the Job Market [PDF]

, 2002
This publication reports our research findings on the factors in women's lives that influence their career decision-making and planning, with recommendations on how service providers and policy-makers can work to promote career development for lower ...

core  

Promoting Active and Sustained School-Business Partnerships: An Exploratory Case Study of an IT Academy

, 2017
In support of the national push for promoting career readiness, school-business partnerships have been noted as an important support strategy. However, there is limited research in the context of career academies. Thus, we sought to explore the nature of
Brookins, Simone J., Fletcher, Edward C, Jr., Hernandez-Gantes, Victor M.   +2 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Relationship between organizational career management and individual performance [PDF]

, 2004
This paper looks at organizational career management and individual performance among insurance salespeople in Kedah. The objective of the paper is to determine whether there is a relationship between organizational career management and comprised ...
Meruda, Nura, Othman, Siti Zubaidah, Yahya, Khulida Kirana   +2 more
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Higher education, job or entrepreneurship? Rural high school learners’ perceptions of post-matric options in Mpumalanga, South Africa

African Journal of Career Development
Background: Making post-matric and career decisions is a significant challenge for rural high school learners in South Africa, where access to career assessments, information and professional guidance is limited.
Percyval Bayane, Bright Smith, Enid Manyaku Pitsoane, Kgomotso Nyamakazi   +3 more
doaj   +1 more source

Cultures of career development: senior leaders' and early career teachers' views of career [PDF]

, 2010
Background The TDA-funded NQT Quality Improvement Study is a 4 year, England-wide longitudinal, combined methods study of both SLT and early career teachers (ECT's) views of key issues in the first few years of teaching.
Coldwell, Michael, Maxwell, Brownwen, McCaig, Colin   +2 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

How the internet changed career: framing the relationship between career development and online technologies [PDF]

, 2012
This article examines the inter-relationship between the internet and career development. It asks three inter-linked questions: How does the internet reshape the context within which individuals pursue their career?
Hooley, Tristram
core   +1 more source