Results 91 to 100 of about 95,653 (214)

Influence of Research Continuity on Physician-Scientists' Career Success. [PDF]

Neurology, 2021
Brownrout J, Norato G, Bensken W, Squirewell C, Gordon T, Heiss J, Nath A, Khan OI.   +7 more
europepmc   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Career success for women in academic medicine: eight self-help strategies. [PDF]

Br J Anaesth
Mehta S, Barrett K, Menon K.
europepmc   +1 more source

Alma mat(t)er(s): Determinants of early career success in economics. [PDF]

PLoS One, 2022
Popov SV.
europepmc   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

The mediating role of achievement motivation in the impact of clinical nurses' individual-organizational fit on career success. [PDF]

Front Psychol
Liu R, Lv J, Meng D, Hu A.
europepmc   +1 more source

Agile Leadership and Perceived Career Success: The Mediating Role of Job Embeddedness. [PDF]

Int J Environ Res Public Health, 2022
Akkaya B, Panait M, Apostu SA, Kaya Y.
europepmc   +1 more source

Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer

Advanced Science, EarlyView.
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen, Dingru Li, Yingna Liao, Zehua Wang, Chunbin Zhu, Zifeng Zhang, Liquan Jin, Yueyue Chen, Jiaoshun Chen, Junyi Xu, Miaoyan Wei, Rong Tang, Xianjun Yu, Si Shi   +13 more
wiley   +1 more source

Person-organization fit and career success among high-level talents in medical and health professions: the mediating role of calling-a cross-sectional study. [PDF]

BMC Health Serv Res
Zhang W, Zhu Q, Huang J, He T, Duan J, Xu W, Lv J.   +6 more
europepmc   +1 more source

Career identity and career success among Chinese male nurses: The mediating role of work engagement. [PDF]

J Nurs Manag, 2022
Wu C, Fu MM, Cheng SZ, Lin YW, Yan JR, Wu J, Zhang XY, Cao BH, Du J, Lang HJ.   +9 more
europepmc   +1 more source