Results 51 to 60 of about 2,693 (199)
Cariprazine: a review in schizophrenia
, 2018 Compliance with Ethical StandardsFunding The preparation of this review was not supported by any external funding.Conflicts of interest Karly Garnock-Jones is a salaried employee of Adis/Springer, is responsible for the article content and declares no ...
Karly Garnock-Jones (4985351)
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European Psychiatry, 2022 Introduction Affective symptoms are a common feature of schizophrenia and define bipolar disorder. Alterations in dopamine neurotransmission and activity at D3-D2 receptors is associated with depressive symptoms providing the rationale for targeting D3 ...
R. Mcintyre +3 more
doaj +1 more source
Mechanism of action of cariprazine [PDF]
CNS Spectrums, 2016 Cariprazine is a new therapeutic agent recently approved for the treatment of both schizophrenia and manic or mixed episodes associated with bipolar disorder, and is under investigation for the treatment of both bipolar depression and major depressive disorder.
openaire +2 more sources
Medicinal Research Reviews, EarlyView.ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu +15 more
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The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.Abstract Accurate drug concentration measurement is essential for precision pharmacotherapy, but conventional therapeutic drug monitoring (TDM) requires venous sampling, increasing patient burden, and potentially limiting participation in TDM and model‐informed precision dosing (MIPD).
Hari Prabhath Tummala +5 more
wiley +1 more source
Review of cariprazine in management of psychiatric illness
, 2017 Schizophrenia and bipolar disorder are severe and debilitating psychiatric disorders. Despite the availability of numerous antipsychotic drugs, many patients still experience poor outcomes and treatment-limiting adverse side effects.
Kristen N. Gardner +3 more
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CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting
Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 412-419, August 2026.CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park +2 more
wiley +1 more source
Role Of Cariprazine In Schizophrenia: A Review [PDF]
Schizophrenia is a severe mental illness and is most commonly observed/ encountered by the majority of clinicians during their clinical practice Among numerous treatment methods, Cariprazine, and its related drugs have shown their clinical efficacy in ...
Ayush Kumar +5 more
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Evaluation of the Effect of Cariprazine on Memory and Cognition in Experimental Rodent Models
, 2022 The main symptoms of schizophrenia are categorized as positive, negative, and cognitive. Cognitive impairments do not generally respond to antipsychotics.
Vilmosh, Natalia Borisova +7 more
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Efficacy and safety of cariprazine augmentation in patients treated with clozapine: a pilot study [PDF]
, 2022 Background: Cariprazine, a novel antipsychotic drug is a partial agonist of dopamine D2/D3 receptors with preferential binding to the D3 receptor. There has been an increasing interest in cariprazine augmentation to clozapine, however the evidence thus ...
Raza-Syed, Ali +6 more
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