Results 51 to 60 of about 2,979 (199)
Cariprazine in the treatment of psychosis with comorbid cannabis use: A case report
Psychiatry Research Communications, 2022 Past literature highlights that cannabis use increase the risk of developing psychotic disorder. In this case report, the authors describe the employment of cariprazine in the treatment of a young adult male affected by psychosis and co-morbid cannabis ...
Alessandro Gentile +4 more
doaj +1 more source
Review of cariprazine in management of psychiatric illness
, 2017 Schizophrenia and bipolar disorder are severe and debilitating psychiatric disorders. Despite the availability of numerous antipsychotic drugs, many patients still experience poor outcomes and treatment-limiting adverse side effects.
Kristen N. Gardner +3 more
core +1 more source
Dopamine Receptor Partial Agonists: Do They Differ in Their Clinical Efficacy?
Frontiers in Psychiatry, 2022 Dopamine receptor partial agonists (DRPAs; aripiprazole, brexpiprazole, and cariprazine) constitute a novel class of antipsychotics. Although they share a similar mechanism of action, DRPAs differ in their pharmacodynamics, pharmacokinetics, drug ...
Pavel Mohr +4 more
doaj +1 more source
Evaluation of the Effect of Cariprazine on Memory and Cognition in Experimental Rodent Models
, 2022 The main symptoms of schizophrenia are categorized as positive, negative, and cognitive. Cognitive impairments do not generally respond to antipsychotics.
Vilmosh, Natalia Borisova +7 more
core +1 more source
European Psychiatry, 2022 Introduction Affective symptoms are a common feature of schizophrenia and define bipolar disorder. Alterations in dopamine neurotransmission and activity at D3-D2 receptors is associated with depressive symptoms providing the rationale for targeting D3 ...
R. Mcintyre +3 more
doaj +1 more source
Cariprazine on Psychosis: Beyond Schizophrenia – A Case Series
Neuropsychiatric Disease and Treatment, 2022 Miguel Bajouco,1– 3 David Mota1,2 1Department of Psychiatry, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; 2Institute of Psychological Medicine, Faculty of Medicine, University of Coimbra, Coimbra, Portugal; 3Coimbra Institute for ...
Bajouco M, Mota D
doaj
Mechanism of action of cariprazine [PDF]
CNS Spectrums, 2016 Cariprazine is a new therapeutic agent recently approved for the treatment of both schizophrenia and manic or mixed episodes associated with bipolar disorder, and is under investigation for the treatment of both bipolar depression and major depressive disorder.
openaire +2 more sources
Medicinal Research Reviews, EarlyView.ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu +15 more
wiley +1 more source
Role Of Cariprazine In Schizophrenia: A Review [PDF]
Schizophrenia is a severe mental illness and is most commonly observed/ encountered by the majority of clinicians during their clinical practice Among numerous treatment methods, Cariprazine, and its related drugs have shown their clinical efficacy in ...
Ayush Kumar +5 more
core +1 more source
Energetic dysregulations in psychotic disorders: Targets for new therapeutics
The FEBS Journal, EarlyView.The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson +10 more
wiley +1 more source