Results 211 to 220 of about 162,227 (374)

Trimethylamine N‐oxide is elevated in postmenopausal women relative to age‐matched men and premenopausal women among individuals with obesity

open access: yesExperimental Physiology, EarlyView.
Abstract Trimethylamine N‐oxide (TMAO) is linked to arterial stiffness and atherosclerosis. Cardiovascular disease (CVD) risk increases following menopause in women. Whether menopause influences plasma TMAO metabolism to mediate CVD risk is unknown.
Daniel J. Battillo, Steven K. Malin
wiley   +1 more source

Antenatal betamethasone impairs markers of cardiac development and function in near‐term lambs

open access: yesExperimental Physiology, EarlyView.
Abstract figure Summary of key molecular differences in the left ventricle of near‐term lambs exposed to antenatal betamethasone, compared to saline. Pregnant ewes received two doses of either saline (Saline) or betamethasone (Betamethasone, intramuscular, 11.4 mg) given 24 h apart, before delivery at 140 days of gestation (dG, term = 150 dG).
Reza Amanollahi   +8 more
wiley   +1 more source

When rehabilitation is not enough, how targeting metabolism can overcome the limited plasticity of skeletal muscle after traumatic injury

open access: yesExperimental Physiology, EarlyView.
Abstract There is a category of large‐scale neuromusculoskeletal injuries that result in long‐term functional disabilities, and one such injury is volumetric muscle loss (VML) injury. In addition to the clinical outcomes related to long‐term dysfunction, co‐morbidities and reduced mobility and physical activity, this review addresses several ...
Sarah M. Greising, Jarrod A. Call
wiley   +1 more source

Early Metabolic Profile in Neonates with Maternal Intrahepatic Cholestasis of Pregnancy. [PDF]

open access: yesChildren (Basel)
Guner Yilmaz B   +13 more
europepmc   +1 more source

Distinct profiles of mitochondrial bioenergetics and redox balance in left atrial and ventricular myocardium in the healthy rat heart

open access: yesExperimental Physiology, EarlyView.
Abstract The left ventricle (LV) is the primary pumping chamber of the heart, generating high systolic pressure to sustain systemic circulation. LV contractile dysfunction is a hallmark of various cardiovascular diseases and is associated with mitochondrial dysfunction, characterised by decreased oxidative phosphorylation (OXPHOS) capacity and ...
Tingting Fang   +3 more
wiley   +1 more source

Structural basis of sodium ion-dependent carnitine transport by OCTN2. [PDF]

open access: yesNat Commun
Davies JS   +5 more
europepmc   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong   +18 more
wiley   +1 more source

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