Results 101 to 110 of about 22,312 (304)

Carnosine Activates Cellular Stress Response in Podocytes and Reduces Glycative and Lipoperoxidative Stress

Biomedicines, 2020
Carnosine improves diabetic complications, including diabetic nephropathy, in in vivo models. To further understand the underlying mechanism of nephroprotection, we studied the effect of carnosine under glucose-induced stress on cellular stress response ...
Maria Scuto, Angela Trovato Salinaro, Sergio Modafferi, Alessandra Polimeni, Tilman Pfeffer, Tim Weigand, Vittorio Calabrese, Claus Peter Schmitt, Verena Peters   +8 more
doaj   +1 more source

Effect of β-alanine supplementation on 20 km cycling time trial performance [PDF]

, 2014
The effects of β-alanine supplementation on high-intensity cycling performance and capacity have been evaluated, although the effects on longer duration cycling performance are unclear.
Artioli GG, Baguet A, Baron B, Batterham AM, Bellinger PM, Boldyrev AA, Borg GAV, Chung W, Decombaz J, Derave W, Derave W, Dutka TL, Everaert I, Harris RC, Harris RC, Hill CA, Hinckson EA, Hipkiss AR, Hobson RM, Hopkins WG, Hopkins WG, Sale C, Sale C, Sale C, Sale C, Smith AE, Smith AE, St Clair Gibson A, Stellingwerff T, Stout JR, Stout JR, Van Thienen R   +31 more
core   +5 more sources

Zinc, Carnosine, and Neurodegenerative Diseases [PDF]

Nutrients, 2018
Zinc (Zn) is abundantly present in the brain, and accumulates in the synaptic vesicles. Synaptic Zn is released with neuronal excitation, and plays essential roles in learning and memory. Increasing evidence suggests that the disruption of Zn homeostasis is involved in various neurodegenerative diseases including Alzheimer’s disease, a vascular type of
Masahiro Kawahara, Ken-ichiro Tanaka, Midori Kato-Negishi   +2 more
openaire   +2 more sources

Intranasal Carnosine Mitigates α-Synuclein Pathology and Motor Dysfunction in the Thy1-aSyn Mouse Model of Parkinson's Disease.

ACS Chemical Neuroscience, 2021
Parkinson's disease (PD) is a debilitating neurodegenerative disorder. Early symptoms include motor dysfunction and impaired olfaction. Toxic aggregation of α-synuclein (aSyn) in the olfactory bulb (OB) and substantia nigra pars compacta (SNpc) is a ...
Josephine M Brown, L. S. Baker, K. Seroogy, M. Genter   +3 more
semanticscholar   +1 more source

Virocell Necromass Provides Limited Plant Nitrogen and Elicits Rhizosphere Metabolites That Affect Phage Dynamics

Plant, Cell &Environment, EarlyView.
ABSTRACT Bacteriophages impact soil bacteria through lysis, altering the availability of organic carbon and plant nutrients. However, the magnitude of nutrient uptake by plants from lysed bacteria remains unknown, partly because this process is challenging to investigate in the field.
Vlastimil Novak, Michelle C. M. van Winden, Thomas V. Harwood, Rachel Neurath, Suzanne M. Kosina, Katherine B. Louie, Matthew B. Sullivan, Simon Roux, Karsten Zengler, Vivek K. Mutalik, Trent R. Northen   +10 more
wiley   +1 more source

Prevention of Atopic Dermatitis in High‐Risk Infants: A Review of the Role of Lipid‐Based Barrier Repair Therapy

Pediatric Dermatology, EarlyView.
ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan, Marty O. Visscher   +1 more
wiley   +1 more source

Carnosine as a histidine source: Transport and hydrolysis of exogeneous carnosine by rat intestine.

Journal of Nutritional Science and Vitaminology, 1985
Transport and metabolism of L-carnosine (beta-alanyl-L-histidine) were studied in rat small intestine. Carnosine administered orally was found in rat serum as well as small intestine and liver, followed by an increase of histidine. At ten minutes after carnosine infusion per os, the carnosine content of the hepatic portal vein increased with the dose ...
N, Tamaki, T, Ikeda, S, Fujimoto, N, Mizutani   +3 more
openaire   +3 more sources

Hydrogen Sulfide and Carnosine: Modulation of Oxidative Stress and Inflammation in Kidney and Brain Axis

Antioxidants, 2020
Emerging evidence indicates that the dysregulation of cellular redox homeostasis and chronic inflammatory processes are implicated in the pathogenesis of kidney and brain disorders. In this light, endogenous dipeptide carnosine (β-alanyl-L-histidine) and
V. Calabrese, M. Scuto, A. Salinaro, G. Dionisio, S. Modafferi, M. Ontario, V. Greco, S. Sciuto, C. Schmitt, E. Calabrese, V. Peters   +10 more
semanticscholar   +1 more source

Inverting CEST or R1ρ$$ {R}_{1\uprho} $$ data to generate solute spectra without a priori assumptions

Magnetic Resonance in Medicine, Volume 95, Issue 2, Page 1239-1254, February 2026.
Abstract Purpose The goal of CEST imaging is to reveal the underlying tissue composition and exchange. However, quantitative CEST analyses typically require strong assumptions about this same composition and exchange. The goal of this paper is to introduce a new CEST analysis (also applicable to rotating frame relaxation rate R1ρ$$ {R}_{1\uprho ...
Daniel F. Gochberg
wiley   +1 more source

Evaluation of the Transepidermal Penetration of a Carnosine Complex in Gel Formulation by 3D Skin Models

Cosmetics, 2018
Carnosine has several physiological roles, from intracellular pH buffering to antioxidant activities, which all depend on bioavailability. This study was conducted in a human skin 3D model and focuses on the effects of the topical delivery of carnosine ...
Valeria Dissette, Carlo Alberto Bignozzi, Giuseppe Valacchi, Alessandra Pecorelli, Stefano Manfredini, Silvia Vertuani   +5 more
doaj   +1 more source