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Carnosine and the processes of ageing

Maturitas, 2016
The causes of ageing are usually regarded as multifactorial; thus effective regulation might be achieved by intervention at multiple sites. It has been suggested that the endogenous dipeptide carnosine, also available as a food supplement, possesses anti-ageing activity and may achieve its reported age-alleviating effects via a number of mechanisms ...
Alan R, Hipkiss   +2 more
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Carnosine in Nucleated Erythrocytes

Nature, 1974
IN the course of studies of the metabolism of intracerebrally administered L-U-14C-histidine in brains of mice and frogs (Rana pipiens), analyses were also performed on blood samples from the injected animals. The mice received 1.5×106 c.p.m. of the labelled histidine, and 1 h later samples of blood were taken by means of orbital puncture.
J N, Van Balgooy   +2 more
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Carnosine levels in blood

Experientia, 1981
Carnosine levels were determined in chick erythrocytes (2510 nmoles/g cells) and plasma from chick (27 nmoles/ml),rat and rabbit. Carnosine was also measured in rabbit reticulocyte-rich blood (105 nmoles/g cells), normal blood (18 nmoles/g cells) and in bone marrow.
J E, Seely, F D, Marshall
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The subcellular distribution of carnosine, carnosine synthetase, and carnosinase in mouse olfactory tissues

Brain Research, 1979
The dipeptide, carnosine, its synthetic enzyme, carnosine synthetase, and its degradative enzyme, carnosinase, appear to be localized in the cytosol of mouse olfactory bulb and epithelium. Mouse olfactory bulbs and epithelium were prelabeled in vivo with [3H]carnosine following intranasal irrigation with [3H]beta-alanine.
J W, Harding, J V, O'Fallon
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Physiologic Properties of Anserine and Carnosine

American Journal of Physiology-Legacy Content, 1956
Studies were made of physiologic responses to anserine and carnosine, isolated and synthetic, as measured by changes in diastolic, pulse and systolic blood pressure and peripheral blood flow in the cat and dog, and by oxytocic effects on smooth muscle of guinea pig and rabbit.
H M, HINES, D C, SUTFIN
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Carnosine reacts with a glycated protein

Free Radical Biology and Medicine, 2000
Oxidation and glycation induce formation of carbonyl (CO) groups in proteins, a characteristic of cellular aging. The dipeptide carnosine (beta-alanyl-L-histidine) is often found in long-lived mammalian tissues at relatively high concentrations (up to 20 mM).
C, Brownson, A R, Hipkiss
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Carnosine and Carnosinase in Rat Tissue

Nature, 1957
PAPER chromatography has been used for obtaining a qualitative picture of the distribution of carnosine and ‘carnosinase’ in the albino rat.
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Protective effect of carnosine in hyperthermia

Bulletin of Experimental Biology and Medicine, 1997
Under the conditions of hyperthermia, carnosine (β-alanine-l-histidine) normalizes tissue contents of lipid peroxidation products, cytochrome P-450, serotonin, and histamine in rats and increases their survival after extreme hyperthermia.
L I, Deev   +5 more
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Carnosine, carnitine, and Vladimir Gulevich

Journal of Chemical Education, 1974
Vladimir Gulevich was a distinguished biochemist who was responsible for the discovery of several biologically important bases and who inspired some extremely capable students and associated to con...
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Carnosine

2022
Mohamad Fawzi Mahomoodally   +2 more
openaire   +1 more source

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