Topical carnosine gel improves intermittent high-intensity exercise performance in world-class rugby sevens players. [PDF]
J Int Soc Sports NutrBeaven CM +3 more
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Beta-Alanine and Aquagenic Pruritus: Proposed Neuroimmune Mechanism. [PDF]
JMIR DermatolPiserchio N +4 more
europepmc +1 more source
Antioxidant Effects of Carnosine-Enriched Chicken Meat Consumption in Athletes: Modulation of SOD Activity and Superoxide Levels-A Randomized Control Trial. [PDF]
Antioxidants (Basel)Kolobarić N +7 more
europepmc +1 more source
Effect of carnosine or beta-alanine supplementation therapy for prediabetes or type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. [PDF]
BMC Endocr DisordLi N +14 more
europepmc +1 more source
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Carnosine and Carnosine-Related Antioxidants: A Review
Current Medicinal Chemistry, 2005First isolated and characterized in 1900 by Gulewitsch, carnosine ( β-alanyl-L-hystidine) is a dipeptide commonly present in mammalian tissue, and in particular in skeletal muscle cells; it is responsible for a variety of activities related to the detoxification of the body from free radical species and the by-products of membrane lipids ...
Andrea Guiotto +3 more
openaire +4 more sources
Physiology and Pathophysiology of Carnosine
Physiological Reviews, 2013Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal muscle, but also in other excitable tissues. Most animals, except humans, also possess a methylated variant of carnosine, either anserine or ophidine/balenine, collectively called the ...
A. A. Boldyrev, G. Aldini, W. Derave
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Carnosine (β-alanyl-L-histidine) is a small dipeptide with numerous activities, including antioxidant effects, metal ion chelation, proton buffering capacity, and inhibitory effects on protein carbonylation and glycation. Carnosine has been mostly studied in organs where it is abundant, including skeletal muscle, cerebral cortex, kidney, spleen, and ...
Ken-Ichiro, Tanaka, Masahiro, Kawahara
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Carnosine and Diabetic Nephropathy
Current Medicinal Chemistry, 2020Diabetic Nephropathy (DN) is a major complication in patients with type 1 or type 2 diabetes and represents the leading cause of end-stage renal disease. Novel therapeutic approaches are warranted. In view of a polymorphism in the carnosinase 1 gene CNDP1, resulting in reduced carnosine degradation activity and a significant DN risk reduction ...
Verena, Peters +2 more
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Carnosine and the processes of ageing
Maturitas, 2016The causes of ageing are usually regarded as multifactorial; thus effective regulation might be achieved by intervention at multiple sites. It has been suggested that the endogenous dipeptide carnosine, also available as a food supplement, possesses anti-ageing activity and may achieve its reported age-alleviating effects via a number of mechanisms ...
Alan R, Hipkiss +2 more
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Carnosine in Nucleated Erythrocytes
Nature, 1974IN the course of studies of the metabolism of intracerebrally administered L-U-14C-histidine in brains of mice and frogs (Rana pipiens), analyses were also performed on blood samples from the injected animals. The mice received 1.5×106 c.p.m. of the labelled histidine, and 1 h later samples of blood were taken by means of orbital puncture.
J N, Van Balgooy +2 more
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