Carnosine inhibits glioblastoma growth independent from PI3K/Akt/mTOR signaling.
PLoS ONE, 2019 Glioblastoma is a high-grade glioma with poor prognosis even after surgery and standard therapy. Here, we asked whether carnosine (β-alanyl-L-histidine), a naturally occurring dipeptide, exert its anti-neoplastic effect on glioblastoma cells via PI3K/Akt/
Henry Oppermann +4 more
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Protective effects of carnosine on white matter damage induced by chronic cerebral hypoperfusion
Neural Regeneration Research, 2016 Carnosine is a dipeptide that scavenges free radicals, inhibits inflammation in the central nervous system, and protects against ischemic and hypoxic brain damage through its anti-oxidative and anti-apoptotic actions.
Jing Ma +4 more
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Sports foods and dietary supplements for optimal function and performance enhancement in track and field athletes [PDF]
, 2009 Numerous nutritional products are marketed with claims of optimizing athlete health and function and/or enhancing performance. Products that fall under the banner of “Sports Foods” or “Dietary Supplements,” may be used to support performance during ...
Peeling, Peter +4 more
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Efficacy of zinc carnosine in the treatment of colorectal cancer and its potential in combination with immunotherapy in vivo [PDF]
, 2022 Weiwei Tang +6 more
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Poultry Science: Histidine-containing dipeptides (HCDs), such as anserine and carnosine, are enormously beneficial to human health and contribute to the meat flavor in chickens.
Minjun Kim +7 more
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DNA as an enzyme: The effect of imidazole derivatives as cofactors and metal ions as activators or inhibitors [PDF]
, 2003 Objective: a highly sensitive spectrofluorometric method using dichlorofluorescin (LDCF) was employed to study the rate of electron transfer reaction in presence of DNA and some imidazole derivatives. Results: in our experiments, DNA possessed a unique
Bathaie, zahra. +3 more
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Carnosine, carnosinase and kidney diseases
Postępy Higieny i Medycyny Doświadczalnej, 2012 Carnosine (beta-alanyl-L-histidine) is an endogenously synthesized dipeptide which is present in different human tissues, including the kidney. Carnosine is hydrolyzed by the enzyme carnosinase. There are two carnosinase homologues: serum secreted carnosinase and non-specific cytosolic dipeptidase, encoded by the genes CNDP1 and CNDP2 respectively and
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Trehalose–Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis [PDF]
, 2022 Irene Paterniti +7 more
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CARNOSINE CONTENT AND MUSCLE OXIDATIVE STABILITY OF MALE AND FEMALE BROILER CHICKENS [PDF]
Poljoprivreda, 2011 Carnosine is a dipeptide with antioxidative effects in broiler muscles. Its anti-ageing effect has also been determined recently, which is especially important for human health and vitality preservation.
Gordana Kralik +4 more
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