Results 11 to 20 of about 560,339 (380)
Journal of Biological Chemistry, 1969 Abstract Holo acyl carrier protein synthetase transfers 4'-phosphopantetheine from reduced coenzyme A to acyl carrier protein (ACP) apoprotein to form ACP holoprotein (holo-ACP). The specificity of this enzyme was tested by using apopeptides derived from ACP. The apopeptides were derived from holopeptides, those containing 4'-phosphopantetheine, by the
P R Vagelos +2 more
+8 more sources
Moco Carrier and Binding Proteins
Molecules, 2022 The molybdenum cofactor (Moco) is the active site prosthetic group found in numerous vitally important enzymes (Mo-enzymes), which predominantly catalyze 2 electron transfer reactions. Moco is synthesized by an evolutionary old and highly conserved multi-step pathway, whereby the metal insertion reaction is the ultimate reaction step here. Moco and its
Tobias Kruse
openaire +5 more sources
Transport of Proteins into Mitochondria. Posttranslational Transfer of ADP/ATP Carrier into Mitochondria in vitro [PDF]
, 1980 The mitochondrial ADP/ATP carrier is an integral transmembrane protein of the inner membrane. It is synthesized on cytoplasmic ribosomes. Kinetic data suggested that this protein is transferred into mitochondria in a posttranslational manner.
Richard Zimmermann, Walter Neupert
openalex +4 more sources
Journal of Biological Chemistry, 1972 β-Ketoacyl-acyl carrier protein (ACP) synthetase catalyzes the chain elongation step of fatty acid biosynthesis, the condensation of fatty acyl-ACP with malonyl-ACP yielding β-ketoacyl-ACP, CO2, and ACP. This enzyme catalyzes two additional reactions, fatty acyl-CoA-ACP transacylation and the decarboxylation of malonyl-ACP to form acetyl-ACP and CO2 ...
Alfred W. Alberts +2 more
+7 more sources
Carrier Proteins Facilitate the Generation of Antipolysaccharide Immunity via Multiple Mechanisms. [PDF]
mBio, 2022 Capsular polysaccharides (CPSs) are important antigenic targets against bacterial infections. As T-independent antigens, however, CPSs elicit short-lived immune responses in adults and are poorly immunogenic in young children.
Zhang F +4 more
europepmc +2 more sources
Structure, function and dynamics in acyl carrier proteins. [PDF]
PLoS One, 2019 Carrier proteins are four-helix bundles that covalently hold metabolites and secondary metabolites, such as fatty acids, polyketides and non-ribosomal peptides.
Farmer R, Thomas CM, Winn PJ.
europepmc +2 more sources
Predicting substrates for orphan solute carrier proteins using multi-omics datasets. [PDF]
BMC GenomicsSolute carriers (SLC) are integral membrane proteins responsible for transporting a wide variety of metabolites, signaling molecules and drugs across cellular membranes. Despite key roles in metabolism, signaling and pharmacology, around one third of SLC
Zhang Y, Newstead S, Sarkies P.
europepmc +2 more sources
Mass spectral determination of phosphopantetheinylation specificity for carrier proteins in Mycobacterium tuberculosis. [PDF]
FEBS Open Bio, 2016 Phosphopantetheinyl transferases (PPTases) are key elements in the modular syntheses performed by multienzyme systems such as polyketide synthases.
Jung J +3 more
europepmc +2 more sources
Carriers and Antigens: New Developments in Glycoconjugate Vaccines
Vaccines, 2023 Glycoconjugate vaccines have proven their worth in the protection and prevention of infectious diseases. The introduction of the Haemophilus influenzae type b vaccine is the prime example, followed by other glycoconjugate vaccines.
Robert M.F. van der Put +2 more
doaj +1 more source
EXPRESSION AND SIGNIFICANCE OF SECRETORY CARRIER MEMBRANE PROTEIN 2 IN COLORECTAL CANCER [PDF]
精准医学杂志, 2023 Objective To investigate the expression and significance of secretory carrier membrane protein 2 (SCAMP2) in colorectal cancer (CRC). Methods Paraffin tissue samples and clinicopathological data were collected from 309 patients with primary CRC who were ...
QIAO Yehua, GUO Dong, WANG Lu, QU Tingting, ZHANG Xiangyan, XING Xiaoming
doaj +1 more source