Results 31 to 40 of about 8,126,655 (341)
Engineering an AB5 Protein Carrier [PDF]
Scientific Reports, 2018 AbstractThe promise of biologic therapeutics is hindered by the challenge to deliver their activity to biochemically relevant sites within diseased cells. The favourable application of the natural protein carriers of the AB5 toxin family to this challenge has been restricted owing to still unresolved requirements for assembling non-native cargo into ...
Bruce R. Lichtenstein, Birte Höcker
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The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology
Physiology, 2020 Members of the mitochondrial carrier family (SLC25) transport a variety of compounds across the inner membrane of mitochondria. These transport steps provide building blocks for the cell and link the pathways of the mitochondrial matrix and cytosol.
Edmund R. S. Kunji +3 more
semanticscholar +1 more source
Scientific Reports, 2021 Signal peptides and secretory carrier proteins are commonly used to secrete heterologous recombinant protein in Gram-negative bacteria. The Escherichia coli osmotically-inducible protein Y (OsmY) is a carrier protein that secretes a target protein ...
David Gonzalez-Perez +8 more
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Biogenesis of mitochondrial porin [PDF]
, 1990 We review here the present knowledge about the pathway of import and assembly of porin into mitochondria and compare it to those of other mitochondrial proteins.
A. Grossmann +74 more
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Trapping of the Enoyl-Acyl Carrier Protein Reductase–Acyl Carrier Protein Interaction [PDF]
Journal of the American Chemical Society, 2016 An ideal target for metabolic engineering, fatty acid biosynthesis remains poorly understood on a molecular level. These carrier protein-dependent pathways require fundamental protein-protein interactions to guide reactivity and processivity, and their control has become one of the major hurdles in successfully adapting these biological machines.
Tallorin, Lorillee +5 more
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Mitochondrial import receptors for precursor proteins [PDF]
, 1991 The specific targeting of precursor proteins synthesized in the cytosol to various cell organelles is a central aspect of intracellular protein traffic. Several hundred different proteins are imported from the cytosol into the mitochondria.
Attardi +34 more
core +1 more source
Transport proteins (carriers) of mitochondria [PDF]
IUBMB Life, 2008 AbstractMitochondria are subcellular structures essential to the aerobic eukaryotic cell. Their role extends much beyond their basic reactions of oxidative phosphorylation. It encompasses the steps critical for cellular metabolic pathways, for apoptosis, and for other processes such as antiviral signaling.
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Expression and function of Met-tRNAiMet carrier proteins in acute myeloid leukemia [PDF]
Jichu yixue yu linchuang, 2021 Objective To investigate the expression of Met-tRNAiMetcarrier proteins eIF2A, eIF2D and MCTS1 in normal hematopoietic stem cells (HSCs) and acute myeloid leukemia (AML) cells, and to study the effect of carrier proteins on the functions of AML cell ...
SU Peng-zhong, HE Jia-huan, YU Shan, WANG Xiao-shuang, YU Jia
doaj
Membrane transporter genes predict chemoradiotherapy response in patients with cervical cancer [PDF]
Einstein (São Paulo)Introduction: Cervical cancer is the fourth most common cancer in women worldwide. Resistance to chemoradiotherapy in cervical cancer has been widely associated with membrane transport-related genes, particularly those encoding efflux transport proteins,
Natália Gregório Custódio +10 more
doaj +1 more source
Scientific Reports, 2016 In some microorganisms, polyunsaturated fatty acids (PUFAs) are biosynthesized by PUFA synthases characterized by tandem acyl carrier proteins (ACPs) in subunit A. These ACPs were previously shown to be important for PUFA productivity.
S. Hayashi +4 more
semanticscholar +1 more source