Results 11 to 20 of about 9,648,893 (334)
ER targeting of non-imported mitochondrial carrier proteins is dependent on the GET pathway [PDF]
Life Science Alliance, 2021 The GET pathway is required to target non-imported mitochondrial carrier proteins to the endoplasmic reticulum, which prevents their deposition into Hsp42-dependent protein foci.
Tianyao Xiao +2 more
doaj +3 more sources
Regulation of zinc-dependent enzymes by metal carrier proteins [PDF]
BioMetals, 2022 Zn2+ ions are essential in many physiological processes, including enzyme catalysis, protein structural stabilization, and the regulation of many proteins.
Michael W Thompson
exaly +3 more sources
Carrier Proteins Facilitate the Generation of Antipolysaccharide Immunity via Multiple Mechanisms [PDF]
mBio, 2022 Capsular polysaccharides (CPSs) are important antigenic targets against bacterial infections. As T-independent antigens, however, CPSs elicit short-lived immune responses in adults and are poorly immunogenic in young children.
Fan Zhang +4 more
doaj +3 more sources
Structure, function and dynamics in acyl carrier proteins. [PDF]
PLoS ONE, 2019 Carrier proteins are four-helix bundles that covalently hold metabolites and secondary metabolites, such as fatty acids, polyketides and non-ribosomal peptides.
Rohit Farmer +2 more
doaj +3 more sources
A guide to plasma membrane solute carrier proteins [PDF]
FEBS Journal, 2021 This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily of transporter proteins and their roles in human cells. The SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety ...
Giulio Superti-Furga
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Moco Carrier and Binding Proteins
Molecules, 2022 The molybdenum cofactor (Moco) is the active site prosthetic group found in numerous vitally important enzymes (Mo-enzymes), which predominantly catalyze 2 electron transfer reactions. Moco is synthesized by an evolutionary old and highly conserved multi-
Tobias Kruse
doaj +3 more sources
Mitochondrial carrier proteins [PDF]
FEBS Letters, 1994 Ten mitochondrial carriers have been purified from animal mitochondria. They are small proteins with a molecular mass ranging from 28 to 34 kDa on SDS‐PAGE. So far, five of these proteins have been sequenced. Their polypeptide chain consists of three tandemly related sequences of about 100 amino acids.
exaly +3 more sources
Molecular Pharmaceutics, 2018 Vaccines may offer a new treatment strategy for opioid use disorders and opioid-related overdoses. To speed translation, this study evaluates opioid conjugate vaccines containing components suitable for pharmaceutical manufacturing and compares ...
Federico Baruffaldi +2 more
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Predicting substrates for orphan solute carrier proteins using multi-omics datasets [PDF]
BMC GenomicsSolute carriers (SLC) are integral membrane proteins responsible for transporting a wide variety of metabolites, signaling molecules and drugs across cellular membranes. Despite key roles in metabolism, signaling and pharmacology, around one third of SLC
Y. Zhang, S. Newstead, P. Sarkies
doaj +2 more sources
The Two Acyl Carrier Proteins of Enterococcus faecalis Have Nonredundant Functions [PDF]
Journal of Bacteriology, 2022 John E Cronan
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