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Biogenesis of Mitochondrial Metabolite Carriers
Biomolecules, 2020 Metabolite carriers of the mitochondrial inner membrane are crucial for cellular physiology since mitochondria contribute essential metabolic reactions and synthesize the majority of the cellular ATP. Like almost all mitochondrial proteins, carriers have
Patrick Horten +2 more
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Scientific Reports, 2022 Solute carrier transporters are integral membrane proteins, and are important for diverse cellular nutrient transports, metabolism, energy demand, and other vital biological activities.
Eva Smorodina +5 more
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Engineering an AB5 Protein Carrier [PDF]
Scientific Reports, 2018 AbstractThe promise of biologic therapeutics is hindered by the challenge to deliver their activity to biochemically relevant sites within diseased cells. The favourable application of the natural protein carriers of the AB5 toxin family to this challenge has been restricted owing to still unresolved requirements for assembling non-native cargo into ...
Bruce R. Lichtenstein, Birte Höcker
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Trapping of the Enoyl-Acyl Carrier Protein Reductase–Acyl Carrier Protein Interaction [PDF]
Journal of the American Chemical Society, 2016 An ideal target for metabolic engineering, fatty acid biosynthesis remains poorly understood on a molecular level. These carrier protein-dependent pathways require fundamental protein-protein interactions to guide reactivity and processivity, and their control has become one of the major hurdles in successfully adapting these biological machines.
Tallorin, Lorillee +5 more
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Scientific Reports, 2021 Signal peptides and secretory carrier proteins are commonly used to secrete heterologous recombinant protein in Gram-negative bacteria. The Escherichia coli osmotically-inducible protein Y (OsmY) is a carrier protein that secretes a target protein ...
David Gonzalez-Perez +8 more
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Transport proteins (carriers) of mitochondria [PDF]
IUBMB Life, 2008 AbstractMitochondria are subcellular structures essential to the aerobic eukaryotic cell. Their role extends much beyond their basic reactions of oxidative phosphorylation. It encompasses the steps critical for cellular metabolic pathways, for apoptosis, and for other processes such as antiviral signaling.
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Membrane transporter genes predict chemoradiotherapy response in patients with cervical cancer [PDF]
Einstein (São Paulo)Introduction: Cervical cancer is the fourth most common cancer in women worldwide. Resistance to chemoradiotherapy in cervical cancer has been widely associated with membrane transport-related genes, particularly those encoding efflux transport proteins,
Natália Gregório Custódio +10 more
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Expression and function of Met-tRNAiMet carrier proteins in acute myeloid leukemia [PDF]
Jichu yixue yu linchuang, 2021 Objective To investigate the expression of Met-tRNAiMetcarrier proteins eIF2A, eIF2D and MCTS1 in normal hematopoietic stem cells (HSCs) and acute myeloid leukemia (AML) cells, and to study the effect of carrier proteins on the functions of AML cell ...
SU Peng-zhong, HE Jia-huan, YU Shan, WANG Xiao-shuang, YU Jia
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Legionella pneumophila secretes a mitochondrial carrier protein during infection.
PLoS Pathogens, 2012 The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to form
Pavel Dolezal +16 more
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A review on protein based nanocarriers for polyphenols: interaction and stabilization mechanisms
Food Innovation and Advances, 2023 Protein has been used as the carrier for protecting and targeting polyphenols and increasing their shelf-life. Interactions of a protein molecule with polyphenols are important, which change functions and physiochemical properties of the complex and ...
Yun Xiao +6 more
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