Results 51 to 60 of about 8,126,655 (341)

Proteinaceous receptors for the import of mitochondrial precursor proteins [PDF]

, 1984
Mild trypsin treatment of isolated Neurospora mitochondria strongly inhibits their ability to bind and import the precursors of several mitochondrial proteins.
Neupert, Walter, Schleyer, Manfred, Zwizinski, Craig   +2 more
core  

Biogenesis of the mitochondrial phosphate carrier [PDF]

, 1991
The mitochondrial phosphate carrier (PiC) is a member of the family of inner-membrane carrier proteins which are generally synthesized without a cleavable presequence.
Adrian G. S., Aquila H., Aquila H., Arends H., Chen W.-J., Cheng M. K., Daum G., Eilers M., Ferreira G. C., Freeman K. B., Goglia F., Kolbe H. V. J., Kramer R., Liu X., Melton D. A., Murakami K., Nicholson D. W., Pelham H. R. B., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Phelps A., Ricquier D., Ridley R. G., Runswick M. J., Runswick M. J., Schleyer M., Schleyer M., Schleyer M., Schwaiger M., Smagula C. S., Wachter E., Zimmermann R.   +36 more
core   +1 more source

Probing the Phosphopantetheine Arm Conformations of Acyl Carrier Proteins Using Vibrational Spectroscopy

Journal of the American Chemical Society, 2014
Acyl carrier proteins (ACPs) are universal and highly conserved domains central to both fatty acid and polyketide biosynthesis. These proteins tether reactive acyl intermediates with a swinging 4′-phosphopantetheine (Ppant) arm and interact with a suite ...
Matthew N. R. Johnson, C. Londergan, Louise K. Charkoudian   +2 more
semanticscholar   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

carrier protein [PDF]

, 2014
Citation: 'carrier protein' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.CT06814 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Exploiting sulphur-carrier proteins from primary metabolism for 2-thiosugar biosynthesis

Nature, 2014
Sulphur is an essential element for life and is ubiquitous in living systems. Yet how the sulphur atom is incorporated into many sulphur-containing secondary metabolites is poorly understood.
E. Sasaki, Xuan Zhang, H. Sun, M. Lu, Tsung-lin Liu, A. Ou, Jeng-yi Li, Yu-Hsiang Chen, S. Ealick, Hung‐wen Liu   +9 more
semanticscholar   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Tracking carrier protein motions with Raman spectroscopy

Nature Communications, 2019
Acyl carrier proteins (ACPs), a universal and highly conserved carrier of acyl intermediates during fatty acid and polyketide synthesis, are difficult to visualise.
Samuel C. Epstein, Adam R. Huff, Emily S. Winesett, Casey H. Londergan, Louise K. Charkoudian   +4 more
doaj   +1 more source

Immunization Effects of a Novel α-Synuclein-Based Peptide Epitope Vaccine in Parkinson’s Disease-Associated Pathology

Vaccines, 2023
Parkinson’s disease (PD) is a chronic neurodegenerative disease that affects the central nervous system, specifically the motor system. It is mainly caused by the loss of dopamine due to the accumulation of α-synuclein (α-syn) protein in the striatum and
Jun Sung Park, Riaz Ahmad, Kyonghwan Choe, Min Hwa Kang, Tae Ju Park, Myeong Ok Kim   +5 more
doaj   +1 more source

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein [PDF]

, 1991
Processing of endogenously synthesized proteins generates short peptides that are presented by MHC class I molecules to CD8 T lymphocytes. Here it is documented that not only the sequence of the presented peptide but also the residues by which it is ...
Braciale, Chimini, Colbere-Garapin, Del Val, Del Val, Del Val, DeLisi, Falk, Falk, Ganem, Hans-Jürgen Schlicht, Jonjić, Junker, Keil, Margarita Del Val, Matthias J. Reddehase, Nassal, Ou, Parham, Ponta, Reddehase, Reddehase, Rothbard, Rötzschke, Rötzschke, Schlicht, Schlicht, Thomas Ruppert, Townsend, Townsend, Townsend, Townsend, Townsend, Ulrich H. Koszinowski, Van Bleek, Volkmer, Yewdell   +36 more
core   +1 more source