Results 21 to 30 of about 312,617 (308)
Solute carrier transporters are integral membrane proteins, and are important for diverse cellular nutrient transports, metabolism, energy demand, and other vital biological activities.
Eva Smorodina+5 more
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Signal peptides and secretory carrier proteins are commonly used to secrete heterologous recombinant protein in Gram-negative bacteria. The Escherichia coli osmotically-inducible protein Y (OsmY) is a carrier protein that secretes a target protein ...
David Gonzalez-Perez+8 more
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Lipid carrier proteins and ethanol
Ethanol has a pronounced effect on lipid homeostasis. It is our overall hypothesis that certain lipid carrier proteins are targets of acute and chronic ethanol exposure and that perturbation of these proteins induces lipid dysfunction leading to cellular pathophysiology. These proteins include both intracellular proteins and lipoproteins.
Nicolai A. Avdulov+7 more
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Engineering an AB5 Protein Carrier [PDF]
AbstractThe promise of biologic therapeutics is hindered by the challenge to deliver their activity to biochemically relevant sites within diseased cells. The favourable application of the natural protein carriers of the AB5 toxin family to this challenge has been restricted owing to still unresolved requirements for assembling non-native cargo into ...
Birte Höcker+2 more
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Trapping of the Enoyl-Acyl Carrier Protein Reductase–Acyl Carrier Protein Interaction [PDF]
An ideal target for metabolic engineering, fatty acid biosynthesis remains poorly understood on a molecular level. These carrier protein-dependent pathways require fundamental protein-protein interactions to guide reactivity and processivity, and their control has become one of the major hurdles in successfully adapting these biological machines.
Tallorin, Lorillee+5 more
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Expression and function of Met-tRNAiMet carrier proteins in acute myeloid leukemia [PDF]
Objective To investigate the expression of Met-tRNAiMetcarrier proteins eIF2A, eIF2D and MCTS1 in normal hematopoietic stem cells (HSCs) and acute myeloid leukemia (AML) cells, and to study the effect of carrier proteins on the functions of AML cell ...
SU Peng-zhong, HE Jia-huan, YU Shan, WANG Xiao-shuang, YU Jia
doaj
A review on protein based nanocarriers for polyphenols: interaction and stabilization mechanisms
Protein has been used as the carrier for protecting and targeting polyphenols and increasing their shelf-life. Interactions of a protein molecule with polyphenols are important, which change functions and physiochemical properties of the complex and ...
Yun Xiao+6 more
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Legionella pneumophila secretes a mitochondrial carrier protein during infection.
The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to form
Pavel Dolezal+16 more
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Insights on the Quest for the Structure–Function Relationship of the Mitochondrial Pyruvate Carrier
The molecular identity of the mitochondrial pyruvate carrier (MPC) was presented in 2012, forty years after the active transport of cytosolic pyruvate into the mitochondrial matrix was first demonstrated.
José Edwin Neciosup Quesñay+8 more
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Transport proteins (carriers) of mitochondria [PDF]
AbstractMitochondria are subcellular structures essential to the aerobic eukaryotic cell. Their role extends much beyond their basic reactions of oxidative phosphorylation. It encompasses the steps critical for cellular metabolic pathways, for apoptosis, and for other processes such as antiviral signaling.
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