Results 21 to 30 of about 312,617 (308)

Structural informatic study of determined and AlphaFold2 predicted molecular structures of 13 human solute carrier transporters and their water-soluble QTY variants

open access: yesScientific Reports, 2022
Solute carrier transporters are integral membrane proteins, and are important for diverse cellular nutrient transports, metabolism, energy demand, and other vital biological activities.
Eva Smorodina   +5 more
doaj   +1 more source

Random and combinatorial mutagenesis for improved total production of secretory target protein in Escherichia coli

open access: yesScientific Reports, 2021
Signal peptides and secretory carrier proteins are commonly used to secrete heterologous recombinant protein in Gram-negative bacteria. The Escherichia coli osmotically-inducible protein Y (OsmY) is a carrier protein that secretes a target protein ...
David Gonzalez-Perez   +8 more
doaj   +1 more source

Lipid carrier proteins and ethanol

open access: yesJournal of Biomedical Science, 2001
Ethanol has a pronounced effect on lipid homeostasis. It is our overall hypothesis that certain lipid carrier proteins are targets of acute and chronic ethanol exposure and that perturbation of these proteins induces lipid dysfunction leading to cellular pathophysiology. These proteins include both intracellular proteins and lipoproteins.
Nicolai A. Avdulov   +7 more
openaire   +3 more sources

Engineering an AB5 Protein Carrier [PDF]

open access: yesScientific Reports, 2018
AbstractThe promise of biologic therapeutics is hindered by the challenge to deliver their activity to biochemically relevant sites within diseased cells. The favourable application of the natural protein carriers of the AB5 toxin family to this challenge has been restricted owing to still unresolved requirements for assembling non-native cargo into ...
Birte Höcker   +2 more
openaire   +4 more sources

Trapping of the Enoyl-Acyl Carrier Protein Reductase–Acyl Carrier Protein Interaction [PDF]

open access: yesJournal of the American Chemical Society, 2016
An ideal target for metabolic engineering, fatty acid biosynthesis remains poorly understood on a molecular level. These carrier protein-dependent pathways require fundamental protein-protein interactions to guide reactivity and processivity, and their control has become one of the major hurdles in successfully adapting these biological machines.
Tallorin, Lorillee   +5 more
openaire   +5 more sources

Expression and function of Met-tRNAiMet carrier proteins in acute myeloid leukemia [PDF]

open access: yesJichu yixue yu linchuang, 2021
Objective To investigate the expression of Met-tRNAiMetcarrier proteins eIF2A, eIF2D and MCTS1 in normal hematopoietic stem cells (HSCs) and acute myeloid leukemia (AML) cells, and to study the effect of carrier proteins on the functions of AML cell ...
SU Peng-zhong, HE Jia-huan, YU Shan, WANG Xiao-shuang, YU Jia
doaj  

A review on protein based nanocarriers for polyphenols: interaction and stabilization mechanisms

open access: yesFood Innovation and Advances, 2023
Protein has been used as the carrier for protecting and targeting polyphenols and increasing their shelf-life. Interactions of a protein molecule with polyphenols are important, which change functions and physiochemical properties of the complex and ...
Yun Xiao   +6 more
doaj   +1 more source

Legionella pneumophila secretes a mitochondrial carrier protein during infection.

open access: yesPLoS Pathogens, 2012
The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to form
Pavel Dolezal   +16 more
doaj   +1 more source

Insights on the Quest for the Structure–Function Relationship of the Mitochondrial Pyruvate Carrier

open access: yesBiology, 2020
The molecular identity of the mitochondrial pyruvate carrier (MPC) was presented in 2012, forty years after the active transport of cytosolic pyruvate into the mitochondrial matrix was first demonstrated.
José Edwin Neciosup Quesñay   +8 more
doaj   +1 more source

Transport proteins (carriers) of mitochondria [PDF]

open access: yesIUBMB Life, 2008
AbstractMitochondria are subcellular structures essential to the aerobic eukaryotic cell. Their role extends much beyond their basic reactions of oxidative phosphorylation. It encompasses the steps critical for cellular metabolic pathways, for apoptosis, and for other processes such as antiviral signaling.
openaire   +3 more sources

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