Results 21 to 30 of about 6,901,957 (346)
BMC Biology, 2020 Background The mitochondrial pyruvate carrier (MPC) plays a central role in energy metabolism by transporting pyruvate across the inner mitochondrial membrane.
Heike Rampelt +9 more
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The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology
Physiology, 2020 Members of the mitochondrial carrier family (SLC25) transport a variety of compounds across the inner membrane of mitochondria. These transport steps provide building blocks for the cell and link the pathways of the mitochondrial matrix and cytosol.
Edmund R. S. Kunji +3 more
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Biogenesis of Mitochondrial Metabolite Carriers
Biomolecules, 2020 Metabolite carriers of the mitochondrial inner membrane are crucial for cellular physiology since mitochondria contribute essential metabolic reactions and synthesize the majority of the cellular ATP. Like almost all mitochondrial proteins, carriers have
Patrick Horten +2 more
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Scientific Reports, 2022 Solute carrier transporters are integral membrane proteins, and are important for diverse cellular nutrient transports, metabolism, energy demand, and other vital biological activities.
Eva Smorodina +5 more
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Scientific Reports, 2021 Signal peptides and secretory carrier proteins are commonly used to secrete heterologous recombinant protein in Gram-negative bacteria. The Escherichia coli osmotically-inducible protein Y (OsmY) is a carrier protein that secretes a target protein ...
David Gonzalez-Perez +8 more
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Expression and function of Met-tRNAiMet carrier proteins in acute myeloid leukemia [PDF]
Jichu yixue yu linchuang, 2021 Objective To investigate the expression of Met-tRNAiMetcarrier proteins eIF2A, eIF2D and MCTS1 in normal hematopoietic stem cells (HSCs) and acute myeloid leukemia (AML) cells, and to study the effect of carrier proteins on the functions of AML cell ...
SU Peng-zhong, HE Jia-huan, YU Shan, WANG Xiao-shuang, YU Jia
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Scientific Reports, 2016 In some microorganisms, polyunsaturated fatty acids (PUFAs) are biosynthesized by PUFA synthases characterized by tandem acyl carrier proteins (ACPs) in subunit A. These ACPs were previously shown to be important for PUFA productivity.
S. Hayashi +4 more
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Membrane transporter genes predict chemoradiotherapy response in patients with cervical cancer [PDF]
Einstein (São Paulo)Introduction: Cervical cancer is the fourth most common cancer in women worldwide. Resistance to chemoradiotherapy in cervical cancer has been widely associated with membrane transport-related genes, particularly those encoding efflux transport proteins,
Natália Gregório Custódio +10 more
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Lipid carrier proteins and ethanol
Journal of Biomedical Science, 2001 Ethanol has a pronounced effect on lipid homeostasis. It is our overall hypothesis that certain lipid carrier proteins are targets of acute and chronic ethanol exposure and that perturbation of these proteins induces lipid dysfunction leading to cellular pathophysiology. These proteins include both intracellular proteins and lipoproteins.
W G, Wood +3 more
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New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis
Angewandte Chemie, 2016 The nonribosomal peptide synthetases (NRPSs) are one of the most promising resources for the production of new bioactive molecules. The mechanism of NRPS catalysis is based around sequential catalytic domains: these are organized into modules, where each
Tiia Kittilä +3 more
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