Results 51 to 60 of about 560,339 (380)

DNA Scaffold Carrier Assisted Protein Translocation Through Solid-State Nanopore [PDF]

arXiv, 2022
The detection of biomolecules at the single molecular level have important applications in the fields of biosensing and biomedical diagnosis. Solid state nanopore (SS-nanopore) is an effective tool to perform the single molecular detection, due to its unique properties of label-free and less sample consumption. The current SS-nanopore translocations of
arxiv  

Mitochondrial precursor proteins are imported through a hydrophilic membrane environment [PDF]

, 1987
We have analyzed how translocation intermediates of imported mitochondrial precursor proteins, which span contact sites, interact with the mitochondrial membranes.
Anderson D., Argan C., Bohni P. C., Daum G., Evans E. A., Gasser S. M., Gilmore R., Guiard B., Hartl F.-U., Hennig B., Hennig B., Hortsch M., Hortsch M., Kaput J., Laemmli U. K., McAda P. C., Miura S., Nicholls D. G., Pelham H. R. B., Pfaller R., Pfaller R., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Pratje E., Riezman H., Sadler I., Schleyer M., Schleyer M., Schmidt B., Schwaiger M., Steck T. L., Stueber D., Wikstrom M., Zwizinski C., Zwizinski C., Zwizinski C.   +38 more
core   +1 more source

Manipulation of Carrier Proteins in Antibiotic Biosynthesis [PDF]

Chemistry & Biology, 2004
Engineering biosynthetic pathways into suitable host organisms has become an attractive venue for the design, evaluation, and production of small molecule therapeutics. Polyketide (PK) and nonribosomal peptide (NRP) synthases have been of particular interest due to their modular structure, yet routine cloning and expression of these enzymes remains ...
Timothy L. Foley, James J. La Clair, Michael D. Burkart, Conor M Regan, Tracy R Schegg   +4 more
openaire   +3 more sources

Synthesis of Length-Tunable DNA Carriers for Nanopore Sensing [PDF]

arXiv, 2023
Molecular carriers represent an increasingly common strategy in the field of nanopore sensing to use secondary molecules to selectively report on the presence of target analytes in solution, allowing for sensitive assays of otherwise hard-to-detect molecules such as small, weakly-charged proteins.
arxiv  

NMR Studies of Escherichia Coli Acyl Carrier Protein: Dynamic and Structural Differences of the Apo- and Holo-forms [PDF]

, 2006
Two indicators of conformational variability of Escherichia coli acyl carrier protein (ACP) have been investigated, namely backbone dynamics and chemical shift variations of ACP.
Eletr, Ziad, Kim, Yangmee, Kovriguine, Evgueni   +2 more
core   +2 more sources

Characterization of Translocation Contact Sites Involved in the Import of Mitochondrial Proteins [PDF]

, 1987
Import of proteins into the mitochondrial matrix requires translocation across two membranes. Translocational intermediates of mitochondrial proteins, which span the outer and inner membrane simultaneously and thus suggest that translocation occurs in ...
Herzog, Volker, Neupert, Walter, Schwaiger, Martin   +2 more
core   +3 more sources

Subcellular localization of the mosquito sterol carrier protein-2 and sterol carrier protein-x [PDF]

Journal of Lipid Research, 2004
Subcellular distribution of Aedes aegypti sterol carrier protein-2 (AeSCP-2) and AeSCP-x was studied using electron microscopy. In both cultured A. aegypti cells and in the larval midgut, AeSCP-2 was detected mostly in the cytosol, with some labeling mitochondria and nucleus, but not in membranous vesicles. The widespread distribution of AeSCP-2 in the
Randall J. Massey, Que Lan
openaire   +4 more sources

HetI-Like Phosphopantetheinyl Transferase Posttranslationally Modifies Acyl Carrier Proteins in Xanthomonas spp.

Molecular Plant-Microbe Interactions, 2022
In Xanthomonas spp., the biosynthesis of the yellow pigment xanthomonadin and fatty acids originates in the type II polyketide synthase (PKS II) and fatty acid synthase (FAS) pathways, respectively. The acyl carrier protein (ACP) is the central component
Yi-Cai Chen, Zhe Hu, Wen-Bin Zhang, Yu Yin, Can-Yao Zhong, Wan-Ying Mo, Yong-Hong Yu, Jin-Cheng Ma, Hai-Hong Wang   +8 more
doaj   +1 more source

Charge transport in purple membrane monolayers: A sequential tunneling approach [PDF]

Physical Review E, 83, 042902 (2011), 2011
Current voltage (I-V) characteristics in proteins can be sensitive to conformational change induced by an external stimulus (photon, odour, etc.). This sensitivity can be used in medical and industrial applications besides shedding new light in the microscopic structure of biological materials. Here, we show that a sequential tunneling model of carrier
arxiv   +1 more source

Acid-Labile Traceless Click Linker for Protein Transduction [PDF]

, 2012
Intracellular delivery of active proteins presents an interesting approach in research and therapy. We created a protein transduction shuttle based on a new traceless click linker that combines the advantages of click reactions with implementation of ...
Bachelder E. M., Dohmen C., Engin K., Ernst Wagner, Frohlich T., Kevin Maier, Lee Y., Meyer M., Meyer M., Meyer M., Miyata K., Murphy R. F., Murthy N., Nieto M. A., Rozema D. B., Rozema D. B., Saxon E., Schaffert D., Vallee M. R., Wagner E., Wagner E., Yu H.   +21 more
core   +1 more source