Trapping of the Enoyl-Acyl Carrier Protein Reductase–Acyl Carrier Protein Interaction [PDF]
Journal of the American Chemical Society, 2016 An ideal target for metabolic engineering, fatty acid biosynthesis remains poorly understood on a molecular level. These carrier protein-dependent pathways require fundamental protein-protein interactions to guide reactivity and processivity, and their control has become one of the major hurdles in successfully adapting these biological machines.
Tallorin, Lorillee +5 more
openaire +4 more sources
Tracking carrier protein motions with Raman spectroscopy
Nature Communications, 2019 Acyl carrier proteins (ACPs), a universal and highly conserved carrier of acyl intermediates during fatty acid and polyketide synthesis, are difficult to visualise.
Samuel C. Epstein +4 more
doaj +1 more source
An Overview on Spray-Drying of Protein-Loaded Polymeric Nanoparticles for Dry Powder Inhalation
Pharmaceutics, 2020 The delivery of therapeutic proteins remains a challenge, despite recent technological advances. While the delivery of proteins to the lungs is the gold standard for topical and systemic therapy through the lungs, the issue still exists.
Tânia Marante +4 more
doaj +1 more source
Characterization of Translocation Contact Sites Involved in the Import of Mitochondrial Proteins [PDF]
, 1987 Import of proteins into the mitochondrial matrix requires translocation across two membranes. Translocational intermediates of mitochondrial proteins, which span the outer and inner membrane simultaneously and thus suggest that translocation occurs in ...
Herzog, Volker +2 more
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Oxidative Protein-Folding Systems in Plant Cells
International Journal of Cell Biology, 2013 Plants are unique among eukaryotes in having evolved organelles: the protein storage vacuole, protein body, and chloroplast. Disulfide transfer pathways that function in the endoplasmic reticulum (ER) and chloroplasts of plants play critical roles in the
Yayoi Onda
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Glucose transporters as markers of diagnosis and prognosis in cancer diseases
Oncology Reviews, 2022 Glucose is a main metabolic substrate, which plays a role as a source of energy and a substrate in several processes. Cell membrane is lipophilic, whereas monosaccharides are hydrophilic.
Leszek Szablewski
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Testing a Recombinant Form of Tetanus Toxoid as a Carrier Protein for Glycoconjugate Vaccines
Vaccines, 2023 Glycoconjugate vaccines play a major role in the prevention of infectious diseases worldwide, with significant impact on global health, enabling the polysaccharides to induce immunogenicity in infants and immunological memory.
Davide Oldrini +14 more
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Scalable Production of Highly-Sensitive Nanosensors Based on Graphene Functionalized with a Designed G Protein-Coupled Receptor [PDF]
, 2014 We have developed a novel, all-electronic biosensor for opioids that consists of an engineered mu opioid receptor protein, with high binding affinity for opioids, chemically bonded to a graphene field-effect transistor to read out ligand binding.
Crook, Alexander +10 more
core +4 more sources
Protein insertion into the inner membrane of mitochondria: routes and mechanisms
FEBS Open BioThe inner membrane of mitochondria contains hundreds of different integral membrane proteins. These proteins transport molecules into and out of the matrix, they carry out multifold catalytic reactions and they promote the biogenesis or degradation of ...
Büsra Kizmaz +3 more
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Assembly and Transfer of Iron–Sulfur Clusters in the Plastid
Frontiers in Plant Science, 2018 Iron-Sulfur (Fe-S) clusters and proteins are essential to many growth and developmental processes. In plants, they exist in the plastids, mitochondria, cytosol, and nucleus.
Yan Lu
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