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Linking Cellular and Mechanical Processes in Articular Cartilage Lesion Formation: A Mathematical Model [PDF]
, 2016 A severe application of stress on articular cartilage can initiate a cascade of biochemical reactions that can lead to the development of osteoarthritis.
Ayati, Bruce P. +4 more
core +5 more sources
Recent Progress in Cartilage Lubrication [PDF]
Advances in Materials, 2021 Healthy articular cartilage, covering the ends of bones in major joints such as hips and knees, presents the most efficiently‐lubricated surface known in nature, with friction coefficients as low as 0.001 up to physiologically high pressures.
Weifeng Lin, J. Klein
semanticscholar +1 more source
Scientific Reports, 2021 Knee cartilage is in an aqueous environment filled with synovial fluid consisting of water, various nutrients, and ions to maintain chondrocyte homeostasis.
Bong Soo Kyung +5 more
doaj +1 more source
Military Medical Research, 2022 Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting a variety of cell types, whose activity and interplay must be precisely mediated for effective healing post-injury.
Y. Xiong +13 more
semanticscholar +1 more source
Cartilage Homeostasis and Osteoarthritis
International Journal of Molecular Sciences, 2022 Healthy limb joints are important for maintaining health and attaining longevity. Endochondral ossification (the replacement of cartilage with bone, occurring during skeletal development) is essential for bone formation, especially in long-axis bones. In
Y. Fujii +5 more
semanticscholar +1 more source
New frontiers for cartilage repair, joint preservation and prevention
Journal of Cartilage & Joint Preservation, 2022 Damaged cartilage is seen with increasing frequency after joint trauma, alone or in combination with other joint injuries. A poor healing of injured cartilage leads to great disability and pain and could by time develop into osteoarthritis (OA).
Mats Brittberg
doaj +1 more source
Journal of Immunology Research, 2022 Variations in the vitamin D receptor (VDR) gene are related to several inflammatory disorders. However, the potential links between such alternations and the risk of developing late fracture-related infection (FRI) remain unclear. This study investigated
Xing-qi Zhao +6 more
doaj +1 more source
Repairing a critical cranial defect using WISP1-pretreated chondrocyte scaffolds
Journal of Tissue Engineering, 2023 In cranial flat bone fractures, spontaneous bone repair will occur only when the fracture ends are in close contact. However, in cases wherein bone discontinuity is extensive, surgical interventions are often required.
Idan Carmon +9 more
doaj +1 more source
npj Regenerative Medicine, 2021 Articular cartilage is susceptible to damage but hard to self-repair due to its avascular nature. Traditional treatment methods are not able to produce satisfactory effects.
Kangkang Zha +8 more
semanticscholar +1 more source
The Role of Senescence-Associated Secretory Phenotype in Bone Loss
Frontiers in Cell and Developmental Biology, 2022 As the population of most nations have a large proportion of older individuals, there is an increase in the prevalence of osteoporosis. Consequently, scientists have focused their attention on the pathogenic mechanisms of osteoporosis.
Runjiu Zhu +10 more
doaj +1 more source