Results 1 to 10 of about 522,337 (336)
Cartilage organoids for cartilage development and cartilage-associated disease modeling
Frontiers in Cell and Developmental Biology, 2023 Cartilage organoids have emerged as powerful modelling technology for recapitulation of joint embryonic events, and cartilage regeneration, as well as pathophysiology of cartilage-associated diseases. Recent breakthroughs have uncovered “mini-joint” models comprising of multicellular components and extracellular matrices of joint cartilage for ...
Weiping Lin +8 more
openaire +3 more sources
Scientific Reports, 2021 Knee cartilage is in an aqueous environment filled with synovial fluid consisting of water, various nutrients, and ions to maintain chondrocyte homeostasis.
Bong Soo Kyung +5 more
doaj +1 more source
Triticeal cartilage: the forgotten cartilage [PDF]
Surgical and Radiologic Anatomy, 2017 The triticeal cartilage (TC) is a small cartilage found within the thyrohyoid membrane. The TC has a variable prevalence between and within individuals. It has been suggested that absence of a TC results from its failure to separate from the superior horn of the thyroid cartilage (SHTC) and that individuals without a TC will have a longer SHTC.
Wilson, Iain +5 more
openaire +5 more sources
Cartilage‐on‐cartilage versus metal‐on‐cartilage impact characteristics and responses [PDF]
Journal of Orthopaedic Research, 2013 AbstractA common in vitro model for studying acute mechanical damage in cartilage is to impact an isolated osteochondral or cartilage specimen with a metallic impactor. The mechanics of a cartilage‐on‐cartilage (COC) impact, as encountered in vivo, are likely different than those of a metal‐on‐cartilage (MOC) impact.
Jessica E. Goetz +6 more
openaire +3 more sources
Journal of Immunology Research, 2022 Variations in the vitamin D receptor (VDR) gene are related to several inflammatory disorders. However, the potential links between such alternations and the risk of developing late fracture-related infection (FRI) remain unclear. This study investigated
Xing-qi Zhao +6 more
doaj +1 more source
Repairing a critical cranial defect using WISP1-pretreated chondrocyte scaffolds
Journal of Tissue Engineering, 2023 In cranial flat bone fractures, spontaneous bone repair will occur only when the fracture ends are in close contact. However, in cases wherein bone discontinuity is extensive, surgical interventions are often required.
Idan Carmon +9 more
doaj +1 more source
Journal of the American Academy of Orthopaedic Surgeons, 2013 Cartilage damaged by trauma has a limited capacity to regenerate. Current methods of managing small chondral defects include palliative treatment with arthroscopic débridement and lavage, reparative treatment with marrow-stimulation techniques (eg, microfracture), and restorative treatment, including osteochondral grafting and autologous chondrocyte ...
Rocky S, Tuan +2 more
openaire +2 more sources
The Role of Senescence-Associated Secretory Phenotype in Bone Loss
Frontiers in Cell and Developmental Biology, 2022 As the population of most nations have a large proportion of older individuals, there is an increase in the prevalence of osteoporosis. Consequently, scientists have focused their attention on the pathogenic mechanisms of osteoporosis.
Runjiu Zhu +10 more
doaj +1 more source
Journal of Orthopaedic Research, 2013 ABSTRACTmicroRNAs are small non‐coding RNAs that in the last decade have emerged as overarching regulators of gene expression. Their abundance, ability to repress a large number of target genes and overlapping target specificity indicate a complex network of interactions that is still being defined.
Gary Gibson, Hiroshi Asahara
openaire +3 more sources
Scientific Reports, 2017 Cartilage tissue is avascular and hypoxic which regulates chondrocyte phenotype via stabilization of HIFs. Here, we investigated the role of hypoxia and HIFs in regulation of Rho and canonical Wnt signaling in chondrocytes.
Ece Öztürk +4 more
doaj +1 more source