Semantic Context Forests for Learning-Based Knee Cartilage Segmentation in 3D MR Images [PDF]
, 2013 The automatic segmentation of human knee cartilage from 3D MR images is a useful yet challenging task due to the thin sheet structure of the cartilage with diffuse boundaries and inhomogeneous intensities. In this paper, we present an iterative multi-class learning method to segment the femoral, tibial and patellar cartilage simultaneously, which ...
A Montillo +14 more
arxiv +3 more sources
A Measure of Control for Secondary Cytokine-Induced Injury of Articular Cartilage: A Computational Study [PDF]
arXiv, 2013 In previous works, the author and collaborators establish a mathematical model for injury response in articular cartilage. In this paper we use mathematical software and computational techniques, applied to an existing model to explore in more detail how the behavior of cartilage cells is influenced by several of, what are believed to be, the most ...
Graham, Jason M
arxiv +3 more sources
Scientific Reports, 2021 Knee cartilage is in an aqueous environment filled with synovial fluid consisting of water, various nutrients, and ions to maintain chondrocyte homeostasis.
Bong Soo Kyung +5 more
doaj +1 more source
Journal of Immunology Research, 2022 Variations in the vitamin D receptor (VDR) gene are related to several inflammatory disorders. However, the potential links between such alternations and the risk of developing late fracture-related infection (FRI) remain unclear. This study investigated
Xing-qi Zhao +6 more
doaj +1 more source
Cell sources for articular cartilage repair strategies: shifting from mono-cultures to co-cultures [PDF]
, 2013 The repair of articular cartilage is challenging due to the sparse native cell population combined with the avascular and aneural nature of the tissue. In recent years cartilage tissue engineering has shown great promise.
Blitterswijk, C.A. van +4 more
core +12 more sources
Low-intensity pulsed ultrasound promotes mesenchymal stem cell transplantation-based articular cartilage regeneration via inhibiting the TNF signaling pathway [PDF]
Stem Cell Res Ther 14, 93 (2023), 2021 Background: Mesenchymal stem cell (MSC) transplantation therapy is highly investigated for the regenerative repair of cartilage defects. Low-intensity pulsed ultrasound (LIPUS) has the potential to promote chondrogenic differentiation of MSCs. However, its underlying mechanism remains unclear.
arxiv +1 more source
Repairing a critical cranial defect using WISP1-pretreated chondrocyte scaffolds
Journal of Tissue Engineering, 2023 In cranial flat bone fractures, spontaneous bone repair will occur only when the fracture ends are in close contact. However, in cases wherein bone discontinuity is extensive, surgical interventions are often required.
Idan Carmon +9 more
doaj +1 more source
Tenascin-C fragments are endogenous inducers of cartilage matrix degradation [PDF]
, 2011 Cartilage destruction is a hallmark of osteoarthritis (OA) and is characterized by increased protease activity resulting in the degradation of critical extracellular matrix (ECM) proteins essential for maintaining cartilage integrity.
Hermansson, M +5 more
core +1 more source
Use of autologous adipose-derived mesenchymal stem cells for creation of laryngeal cartilage [PDF]
, 2017 OBJECTIVES/HYPOTHESIS: Adipose-derived mesenchymal stem cells (ASCs) are an exciting potential cell source for tissue engineering because cells can be derived from the simple excision of autologous fat.
Brookes, Sarah +6 more
core +1 more source
Dickkopf-3 is upregulated in osteoarthritis and has a chondroprotective role [PDF]
, 2015 Objective Dickkopf-3 (Dkk3) is a non-canonical member of the Dkk family of Wnt antagonists and its upregulation has been reported in microarray analysis of cartilage from mouse models of osteoarthritis (OA).
Barter, Matthew +8 more
core +1 more source