Results 141 to 150 of about 151,261 (309)
Detection of Proteoglycan Loss from Articular Cartilage using Brillouin Microscopy, with Applications to Osteoarthritis [PDF]
arXiv, 2018 The degeneration of articular cartilage (AC) occurs in osteoarthritis (OA), which is a leading cause of pain and disability in middle-aged and older people. The early disease related changes in cartilage extra-cellular matrix (ECM) start with depletion of proteoglycan(PG), leading to an increase in tissue hydration and permeability.
arxiv
The Anatomical Record, EarlyView.Abstract Basking sharks, Cetorhinus maximus (Gunnerus, Brugden [Squalus maximus], Det Kongelige Norske Videnskabers Selskabs Skrifter, 1765, vol. 3, pp. 33–49), feed by gaping their mouths and gill slits, greatly reorienting their cranial skeletons to filter food from water.
Tairan Li +12 more
wiley +1 more source
The Effects of Splayed Lipid Molecules on Lubrication by Lipid Bilayers [PDF]
The outstanding lubrication of articular cartilage in the major synovial joints such as hips and knees, essential for the joint well-being, has been attributed to boundary layers of lipids at the outer cartilage surfaces, which have very low friction mediated by the hydration lubrication mechanism at their highly hydrated exposed headgroups.
arxiv +1 more source
Sequential expression of Lgr5 and Col22a1 in developing synovial joints marks the progressive differentiation of progenitor cells to articular chondrocytes [PDF]
, 2014 Poster Presentation - Theme 3: Development & stem cellsHealthy articular cartilage in synovial joints provides a smooth, wear-resistant structure that reduces friction and absorbs impact forces.
Chan, D, Feng, C
core
An overview of the postcranial osteology of caecilians (Gymnophiona, Lissamphibia)
The Anatomical Record, EarlyView.Abstract Caecilians comprise a relatively small (~220 species) group (Gymnophiona) of snake‐like or worm‐like, mostly tropical amphibians. Most adult caecilians are fossorial, although some species may live in aquatic or semi‐aquatic environments, either as larvae or adults.
Rodolfo Otávio Santos +2 more
wiley +1 more source
Metabolomic analysis reveals the molecular mechanism related to leg abnormality in broilers
Animal Research and One Health, EarlyView.The graphical abstract shows the principal results of this study. Compared to the leg normal broilers, the serum calcium to phosphorus ratio was extremely decreased in the group with deformed leg bones. Additionally, a total of nine differential metabolites significantly associated with leg abnormalities and serum calcium and phosphorus levels were ...
Jumei Zheng +9 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Chondrocytemetabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein posttranslational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK), and its regulator sirtuin 5 (Sirt5) in OA ...
Huanhuan Liu +11 more
wiley +1 more source
Dynamic Compression Improves Chondrogenesis in the Tissue Engineered Model of Cartilage
Biotechnology and Bioengineering, EarlyView.ABSTRACT Hyaline cartilage is a dense avascular tissue with low regenerative potential, present at the ends of the diarthrodial joints and in the cartilage growth plate. Skeletal diseases often result from extracellular changes in this tissue; however, studies of these are hindered by the tissue complexity, the difficulty in obtaining human material ...
Marc V. Farcasanu +8 more
wiley +1 more source
Influence of applied stress on energy dissipation and crack growth in articular cartilage [PDF]
arXivMechanical stress-induced damage to the articular cartilage can result in fracture imitation or significant tissue degeneration leading to osteoarthritis (OA) compromising joint mobility. Despite the clinical significance, a comprehensive understanding of the crack progression in cartilage damage remains elusive due to complex mechanical responses and ...
arxiv